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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
Medtr8g020840.1 |
| Common Name | NSP1 |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
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| Family |
GRAS |
| Protein Properties |
Length: 555aa MW: 61826.7 Da PI: 6.0415 |
| Description |
GRAS family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| Medtr8g020840.1 | genome | Mt | View CDS |
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| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | GRAS | 245.5 | 2.1e-75 | 169 | 548 | 2 | 374 |
GRAS 2 velLlecAeavssgdlelaqalLarlselaspdgdpmqRlaayfteALaarlarsvselykalppsetseknsseelaalklfsevsPilkfsh 95
++lL cA a++ g+l+++q+lL l+elas +gd+++Rlaa+ ++AL ++l++s+s++ + + +++ + ++l f+e sP++ f +
Medtr8g020840.1 169 EQLLNPCAVAITGGNLNRVQHLLYVLHELASTTGDANHRLAAHGLRALTHHLSSSSSSTPSGTITFAST--EPRFFQKSLLKFYEFSPWFSFPN 260
689***************************************************666666555444444..34555555556************ PP
GRAS 96 ltaNqaIleavege....ervHiiDfdisqGlQWpaLlqaLasRp.egppslRiTgvgspesg...........skeeleetgerLakfAeelg 173
+aN Il+ +++e +++Hi+D+++s+G+QWp++l+aL+ Rp ++pp +R+T+v++++s+ + + L +A++l+
Medtr8g020840.1 261 NIANASILQVLAEEpnnlRTLHILDIGVSHGVQWPTFLEALSRRPgGPPPLVRLTVVNASSSTendqnmetpfsIGPCGDTFSSGLLGYAQSLN 354
************999888999************************55566********98888777665544433333455678899******* PP
GRAS 174 vpfefnvlvakrledleleeLrvkpgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadh...nsesFlerflealeyy 264
v+++++ l + l++l+ ++ +++++E+l+V+ +++lh+l ++ ++er+e+Lk++++++Pk v+++e+++++ + ++F+++f++ +ey
Medtr8g020840.1 355 VNLQIKKLDNHPLQTLNAKSVDTSSDETLIVCAQFRLHHLN---HNNPDERSEFLKVLRGMEPKGVILSENNMECccsSCGDFATGFSRRVEYL 445
*******9999*****************************8...55566667********************9886334459************ PP
GRAS 265 salfdsleaklpreseerikvErellgreivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvk.sdgyrveeesgs 357
+ ++ds+++ + ++r + Er++++ e+ ++++++ ++ +e+ ekW er++eaGF ++e+a + ++llrk++ +++++vee+s s
Medtr8g020840.1 446 WRFLDSTSSAF----KNRDSDERKMMEGEAAKALTNQREM----NERREKWCERMKEAGFAGEVFGEDAIDGGRALLRKYDnNWEMKVEENSTS 531
*******8776....6666666667777789999888777....77778********************************9999********* PP
GRAS 358 lvlgWkdrpLvsvSaWr 374
+ l Wk++p+ ++S W+
Medtr8g020840.1 532 VELWWKSQPVSFCSLWK 548
****************8 PP
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| Sequence ? help Back to Top |
| Protein Sequence Length: 555 aa
Download sequence Send
to blast |
MTMEPNPTSD HILDWLEGSV SFFPSFLDDP YNNGYIHEYE IWNQNQDISN QYQIDANTNS 60
SNATNSTTNI VAASTTTSTT SLEPNSFNNI PFSDLPKKRN AEDELSLKKQ PQNQKNKRLK 120
SRPMNESDNG DAALEGTVVR KSGGNKKGAA KANGSNSNNG NNKDGRWAEQ LLNPCAVAIT 180
GGNLNRVQHL LYVLHELAST TGDANHRLAA HGLRALTHHL SSSSSSTPSG TITFASTEPR 240
FFQKSLLKFY EFSPWFSFPN NIANASILQV LAEEPNNLRT LHILDIGVSH GVQWPTFLEA 300
LSRRPGGPPP LVRLTVVNAS SSTENDQNME TPFSIGPCGD TFSSGLLGYA QSLNVNLQIK 360
KLDNHPLQTL NAKSVDTSSD ETLIVCAQFR LHHLNHNNPD ERSEFLKVLR GMEPKGVILS 420
ENNMECCCSS CGDFATGFSR RVEYLWRFLD STSSAFKNRD SDERKMMEGE AAKALTNQRE 480
MNERREKWCE RMKEAGFAGE VFGEDAIDGG RALLRKYDNN WEMKVEENST SVELWWKSQP 540
VSFCSLWKLD KQPE*
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | TISSUE SPECIFICITY: Expressed in epidermal and cortical root cells. {ECO:0000269|PubMed:15961669}. |
| Functional Description ? help
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| Source |
Description |
| UniProt | Transcriptional regulator essential for Nod-factor-induced gene expression. Acts downstream of calcium spiking. May be a target of DMI3, a calcium/calmodulin-dependent protein kinase (CCaMK) (PubMed:15961669). Is essential for Nod factor-elicited expression of ERN1 (PubMed:23077241). {ECO:0000269|PubMed:15961669, ECO:0000269|PubMed:23077241}. |
| Function -- GeneRIF ? help
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- NSP1 and NSP2 are single-copy genes in legumes, which implies that both proteins fulfill dual regulatory functions to control downstream targets after rhizobium-induced signaling as well as strigolactone biosynthesis in nonsymbiotic conditions.
[PMID: 22039214]
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| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Not induced after treatment with Sinorhizobium meliloti. {ECO:0000269|PubMed:15961669}. |
| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | AC229692 | 0.0 | AC229692.10 Medicago truncatula clone mth2-60b17, complete sequence. |
| GenBank | AJ972473 | 0.0 | AJ972473.1 Medicago truncatula partial NSP1 gene for Nodulation Signaling Pathway 1 protein. |
| GenBank | AJ972478 | 0.0 | AJ972478.1 Medicago truncatula NSP1 gene for Nodulation Signaling Pathway 1 protein. |
| Publications
? help Back to Top |
- Smit P, et al.
NSP1 of the GRAS protein family is essential for rhizobial Nod factor-induced transcription.
Science, 2005. 308(5729): p. 1789-91
[PMID:15961669] - Liu W, et al.
Strigolactone biosynthesis in Medicago truncatula and rice requires the symbiotic GRAS-type transcription factors NSP1 and NSP2.
Plant Cell, 2011. 23(10): p. 3853-65
[PMID:22039214] - Young ND, et al.
The Medicago genome provides insight into the evolution of rhizobial symbioses.
Nature, 2011. 480(7378): p. 520-4
[PMID:22089132] - Cerri MR, et al.
Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
Plant Physiol., 2012. 160(4): p. 2155-72
[PMID:23077241] - Tang H, et al.
An improved genome release (version Mt4.0) for the model legume Medicago truncatula.
BMC Genomics, 2014. 15: p. 312
[PMID:24767513]
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