PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr7g080780.2

Common Name

MTR_7g080780, TSAR1

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

bHLH

Protein Properties

Length: 323aa MW: 36836.8 Da PI: 5.2301

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr7g080780.2	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27	8e-09	153	198	5	55
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 h ++Er+RR+++ + + L ++P + kK++K +L +Av+Y k+Lq Medtr7g080780.2 153 HLMAERKRRRELTENIIALSAMIPGL-----KKMDKCYVLSEAVNYTKQLQ 198 889*********************.....9****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.722	148	197	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	7.7E-14	152	212	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	9.23E-7	153	202	No hit	No description
SuperFamily	SSF47459	2.75E-13	153	212	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.7E-6	153	198	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.3E-8	154	203	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 323 aa Download sequence Send to blast
MEDDVILNQS STTTFDEQEF LKDIILEEPE CIELSSYLCS NKTKDNSTTI INVEGDATSP 60 TNSILSFDET SLFCGDYENV ETNHKSNNSN SIKSLERSCV SSPATYLLSF GNSSIEPIIE 120 PMSHKTKRRT DESRGVKEAT KKVRRSCETV QDHLMAERKR RRELTENIIA LSAMIPGLKK 180 MDKCYVLSEA VNYTKQLQKR IKELENQNKD SKPNPAIFKW KSQVSSNKKK SSESLLEVEA 240 RVKEKEVLIR IHCEKQKDIV LKIHELLEKF NITITSSSML PFGDSILVIN ICAQMDEEDS 300 MTMDDLVENL RKYLLETHES YL*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	157	161	RKRRR

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.19160	0.0	root

Function -- GeneRIF ? help Back to Top
The bHLH transcription factors TSAR1 and TSAR2 regulate triterpene saponin biosynthesis. [PMID: 26589673]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr7g080780.2

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KM409647	0.0	KM409647.1 Medicago truncatula triterpene saponin activating regulator 1 (TSAR1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003624235.1	0.0	transcription factor bHLH18
TrEMBL	G7KSG4	0.0	G7KSG4_MEDTR; Helix loop helix DNA-binding domain protein
TrEMBL	G7KSG5	0.0	G7KSG5_MEDTR; Helix loop helix DNA-binding domain protein
STRING	AES80453	0.0	(Medicago truncatula)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37850.1	7e-35	bHLH family protein

Link Out ? help Back to Top
Phytozome	Medtr7g080780.2
Entrez Gene	11438380

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Mertens J, et al. The bHLH Transcription Factors TSAR1 and TSAR2 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula. Plant Physiol., 2016. 170(1): p. 194-210 [PMID:26589673]