PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

HD-ZIP

Protein Properties

Length: 284aa MW: 32504.3 Da PI: 6.3532

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr5g039000.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	56.9	3.6e-18	77	130	3	56
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 k+++++ eq+++Le+ Fe +++ e++ +LA+ l+L+ rqV +WFqNrRa++k Medtr5g039000.1 77 KKRRLNMEQVKTLEKSFELGNKLEPERKMQLARALNLQPRQVAIWFQNRRARWK 130 456899***********************************************9 PP
2	HD-ZIP_I/II	131.2	4.1e-42	76	166	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 ekkrrl+ eqvk+LE+sFe +kLeperK++lar+L+lqprqva+WFqnrRAR+ktkqlEkdy++Lkr+yda+k +n++L++++++L++e+ Medtr5g039000.1 76 EKKRRLNMEQVKTLEKSFELGNKLEPERKMQLARALNLQPRQVAIWFQNRRARWKTKQLEKDYDVLKRQYDAIKLDNDALQAQNQKLQAEI 166 69**************************************************************************************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	7.7E-20	68	134	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.394	72	132	IPR001356	Homeobox domain
SMART	SM00389	4.6E-18	75	136	IPR001356	Homeobox domain
CDD	cd00086	1.44E-15	77	133	No hit	No description
Pfam	PF00046	1.6E-15	77	130	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	8.6E-19	79	139	IPR009057	Homeodomain-like
PROSITE pattern	PS00027	0	107	130	IPR017970	Homeobox, conserved site
Pfam	PF02183	9.7E-17	132	172	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 284 aa Download sequence Send to blast
MHEMAFFQAN FMLQTPHHHD DHHQPSSLNS ILPQDYHGGP SFLGKRCMSF SSGIELGEEA 60 NIPEEDLSDD GSQAGEKKRR LNMEQVKTLE KSFELGNKLE PERKMQLARA LNLQPRQVAI 120 WFQNRRARWK TKQLEKDYDV LKRQYDAIKL DNDALQAQNQ KLQAEILALK NREPTESINL 180 NKETEGSSSN RSENSSEIKL DMSRTPASDS PLSTHQHTTS RTFFPPSARP SSGIAQLFQT 240 SSRPEIQCQK IDQMVKEESL SNMFCGMDDQ AGFWPWLEQQ HFN*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	124	132	RRARWKTKQ

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.1797	0.0	flower\| leaf\| pod\| root\| stem

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Predominantly expressed in leaves and flowers. {ECO:0000269\|PubMed:16055682}.

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that may act in the sucrose-signaling pathway. {ECO:0000269\|PubMed:11292072}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr5g039000.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	CT571261	0.0	CT571261.1 Medicago truncatula chromosome 5 clone mth2-67l4, COMPLETE SEQUENCE.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003613642.1	0.0	homeobox-leucine zipper protein ATHB-13
Swissprot	Q8LC03	1e-114	ATB13_ARATH; Homeobox-leucine zipper protein ATHB-13
TrEMBL	G7KB59	0.0	G7KB59_MEDTR; Homeobox leucine zipper ATHB-like protein
STRING	AES96600	0.0	(Medicago truncatula)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1271	33	106

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G69780.1	1e-107	HD-ZIP family protein

Link Out ? help Back to Top
Phytozome	Medtr5g039000.1
Entrez Gene	11411421

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Ribone PA,Capella M,Chan RL Functional characterization of the homeodomain leucine zipper I transcription factor AtHB13 reveals a crucial role in Arabidopsis development. J. Exp. Bot., 2015. 66(19): p. 5929-43 [PMID:26136262] Wang X, et al. Overexpressed BRH1, a RING finger gene, alters rosette leaf shape in Arabidopsis thaliana. Sci China Life Sci, 2018. 61(1): p. 79-87 [PMID:28887625] Ebrahimian-Motlagh S, et al. JUNGBRUNNEN1 Confers Drought Tolerance Downstream of the HD-Zip I Transcription Factor AtHB13. Front Plant Sci, 2017. 8: p. 2118 [PMID:29326734]