PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr5g029680.2
Common NameMTR_5g029680
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family HSF
Protein Properties Length: 503aa    MW: 55357.6 Da    PI: 4.4845
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr5g029680.2genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind1149.7e-36331242102
                      HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXX CS
     HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkelle 95 
                      Fl+k+y++++d++++ ++sws+++nsfvv+d+ efa+++Lpk+Fkh+nf+SFvRQLn+YgF+kv+ ++         weF+++ F +g+k+ll+
  Medtr5g029680.2  33 FLSKTYDMVDDPSTDAIVSWSATNNSFVVWDPPEFARDLLPKFFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQKQLLK 117
                      9********************999*****************************************999.........***************** PP

                      XXXXXXX CS
     HSF_DNA-bind  96 kikrkks 102
                      +i r+k 
  Medtr5g029680.2 118 SISRRKP 124
                      ****986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.1E-3924117IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.21E-3528122IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004154.3E-6329122IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004475.7E-3233122IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000568.2E-203356IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000568.2E-207183IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043407296IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000568.2E-208496IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 503 aa     Download sequence    Send to blast
MDGASGGSGG GEGSATQIPA PTPMQNANAP PPFLSKTYDM VDDPSTDAIV SWSATNNSFV  60
VWDPPEFARD LLPKFFKHNN FSSFVRQLNT YGFRKVDPDR WEFANEGFLR GQKQLLKSIS  120
RRKPAHGHTQ QQAQQPHGQS SSVGACVEVG KFGLEEEVER LKRDKNVLMQ ELVRLRQQQQ  180
TTDSQLQTMV QRLQGMEQRQ QQMMSFLAKA VQSPGFFAQF VQQQNDSNRR ITEVNKKRRL  240
KQDGIAETTE QATPPDGQIV KYQPMMNDTA KAMLRKIMKW DTPRVESFNK NPDNYLIGDG  300
TSPSSAMDSN SSTSWNSGVT LQEVPPSSVQ STQFPVATGT QGHIPSSEKP EILSVPQAAA  360
SANVMKDGTH AASTIPTSQA DVIMPDIPSV PEIVPKSILD IPENDYMAPE TDDGFMDPSS  420
LGSLPIDLDC LSPGADIDDL LSSSIWDDLL QTPIPEDFEA NIDEISRGNE VQPTENGWDN  480
NTQPLDQLTE QMGLLSSDAK RI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B4e-283112227129Heat shock factor protein 1
5d5v_B4e-283112227129Heat shock factor protein 1
5d5v_D4e-283112227129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1234241NKKRRLKQ
2235240KKRRLK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.137690.0root
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr5g029680.2
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankDQ9072350.0DQ907235.1 Medicago sativa heat shock transcription factor 1 (HSF1) mRNA, HSF1-b2 allele, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003612845.10.0heat shock factor protein HSF8 isoform X1
SwissprotQ401521e-174HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBLG7KDN60.0G7KDN6_MEDTR; Heat shock transcription factor A3
STRINGAES958030.0(Medicago truncatula)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32330.11e-129heat shock transcription factor A1D
Publications ? help Back to Top
  1. Zhu B, et al.
    Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max).
    J. Plant Res., 2006. 119(3): p. 247-56
    [PMID:16570125]
  2. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  3. Cai SY, et al.
    HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants.
    J. Pineal Res., 2017.
    [PMID:28095626]
  4. Zhou J, et al.
    Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1.
    Plant Physiol., 2018. 176(3): p. 2456-2471
    [PMID:29339397]