PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr5g012080.1
Common NameMTR_5g012080
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family NAC
Protein Properties Length: 350aa    MW: 40487.1 Da    PI: 6.7445
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr5g012080.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM178.81.5e-5571371129
              NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdke 91 
                      +ppGfrFhPtdeelv++yL+kk+++k+++l ++ik+vd+yk+ePwdL++  k+ + e++ewyfFs++dkky+t++r+nratk+g+Wkatg+dk+
  Medtr5g012080.1   7 VPPGFRFHPTDEELVDHYLRKKIASKRIDL-DIIKDVDLYKIEPWDLQElcKIGSdEQTEWYFFSHKDKKYPTSSRTNRATKAGFWKATGRDKA 99 
                      69****************************.99**************954555553455*********************************** PP

              NAM  92 vlskkgelvglkktLvfykgrapkgektdWvmheyrle 129
                      ++s++  l+g++ktLvfykgrap+g+k+dW+mheyrle
  Medtr5g012080.1 100 IYSNHICLIGMRKTLVFYKGRAPNGQKSDWIMHEYRLE 137
                      ***99999****************************85 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019414.45E-604158IPR003441NAC domain
PROSITE profilePS5100558.9377158IPR003441NAC domain
PfamPF023651.1E-288136IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0048759Biological Processxylem vessel member cell differentiation
GO:1901348Biological Processpositive regulation of secondary cell wall biogenesis
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 350 aa     Download sequence    Send to blast
MNNFSHVPPG FRFHPTDEEL VDHYLRKKIA SKRIDLDIIK DVDLYKIEPW DLQELCKIGS  60
DEQTEWYFFS HKDKKYPTSS RTNRATKAGF WKATGRDKAI YSNHICLIGM RKTLVFYKGR  120
APNGQKSDWI MHEYRLETNE NGTTPQEEGW VVCKVFKKRI ATTMRKMDDS PCWYDDQVSF  180
MQSELESPSR ISSHHPYNAS YQHQQQHYPC KQELDQLQYN IHINNNDANN FLQLPQLENL  240
NSPMQCSLST HSMTQEQYGQ QQSMQMLYGG SNDLQAVVEQ SNEWKALDKF VASRLSQDQD  300
HASKGTSSYC NVAQQIALLS NDESKKSETG GQEHVTSISN SNCQIDTWK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3ulx_A4e-50615914169Stress-induced transcription factor NAC1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.247860.0leaf| root
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Up-regulated during xylem vessel element formation. Expressed preferentially in procambial cells adjacent to root meristem. {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:25148240}.
UniprotTISSUE SPECIFICITY: Detected in root vessels of protoxylems, outermost metaxylems, inner metaxylems, shoots and hypocotyls. Expressed in roots, hypocotyls, cotyledons and leaves (PubMed:18445131). Expressed in developing xylems (PubMed:16103214, PubMed:17565617). Specifically expressed in vessels in the secondary xylem of the root-hypocotyl region, and in vessels but not in interfascicular fibers in stems (PubMed:25148240). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:17565617, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:25148240}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls (PubMed:25148240). {ECO:0000250|UniProtKB:Q9LVA1, ECO:0000269|PubMed:25148240}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr5g012080.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankCR9621290.0CR962129.2 Medicago truncatula chromosome 5 clone mth2-28m4, COMPLETE SEQUENCE.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003611265.20.0NAC domain-containing protein 7
RefseqXP_024639296.10.0NAC domain-containing protein 7
SwissprotF4HYV51e-130NAC26_ARATH; NAC domain-containing protein 26
TrEMBLG7KG950.0G7KG95_MEDTR; Putative transcription factor NAM family
STRINGAES942230.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF126933106
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G62700.11e-127Arabidopsis NAC domain containing protein 26
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]