PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr3g110028.2
Common NameMTR_042s0013
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family MYB
Protein Properties Length: 904aa    MW: 100755 Da    PI: 4.8553
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr3g110028.2genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding57.43.3e-183379148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g WT+eEd +l +av+++ g++Wk+Ia+++   Rt+ qc +rwqk+l
  Medtr3g110028.2 33 KGQWTPEEDNILRKAVERFQGKNWKKIAECFK-DRTDVQCLHRWQKVL 79
                     799****************************9.************986 PP
2Myb_DNA-binding66.16.2e-2185131148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g+W++eEde +vd+v+++G++ W+tIa++++ gR +kqc++rw+++l
  Medtr3g110028.2  85 KGPWSKEEDETIVDLVNKYGPKKWSTIAQHLP-GRIGKQCRERWHNHL 131
                      79******************************.*************97 PP
3Myb_DNA-binding51.42.5e-16137179145
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 
                      + +WT+eE++ l++a++ +G++ W+  ++ ++ gRt++ +k++w+
  Medtr3g110028.2 137 KEAWTQEEELALIHAHQIYGNR-WAELSKFLP-GRTDNAIKNHWN 179
                      579*******************.*********.***********8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129417.4772879IPR017930Myb domain
SMARTSM007171.3E-153281IPR001005SANT/Myb domain
PfamPF002491.0E-153379IPR001005SANT/Myb domain
SuperFamilySSF466891.0E-153489IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.604.0E-223592IPR009057Homeodomain-like
CDDcd001671.63E-143679No hitNo description
PROSITE profilePS5129432.51280135IPR017930Myb domain
SuperFamilySSF466895.62E-3282178IPR009057Homeodomain-like
SMARTSM007173.5E-1984133IPR001005SANT/Myb domain
PfamPF002496.9E-1985131IPR001005SANT/Myb domain
CDDcd001671.14E-1687131No hitNo description
Gene3DG3DSA:1.10.10.607.0E-2893138IPR009057Homeodomain-like
PROSITE profilePS5129420.586136186IPR017930Myb domain
SMARTSM007172.2E-16136184IPR001005SANT/Myb domain
PfamPF002491.7E-14137180IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.604.3E-22139186IPR009057Homeodomain-like
CDDcd001678.79E-13139179No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 904 aa     Download sequence    Send to blast
MGSESTIPAL SDGVQKIRAL HGRTTGPTRR STKGQWTPEE DNILRKAVER FQGKNWKKIA  60
ECFKDRTDVQ CLHRWQKVLN PELIKGPWSK EEDETIVDLV NKYGPKKWST IAQHLPGRIG  120
KQCRERWHNH LNPSINKEAW TQEEELALIH AHQIYGNRWA ELSKFLPGRT DNAIKNHWNS  180
SVKKKLDSYL ASGLLAQFQN VPLVGNPNQP IASSSARLQF SVDDNGPRGT EGEEVSQCSQ  240
ESINASHFPS GRELSIAVIQ NVEEYRQNEE SNQASCSEPY YMSLDGVTLQ EVCSSQFLEQ  300
KYSNEPGSSS ANVDCQFNLH ALPTSLDFGQ ESTQLQNDSL ASGENMMIVP YEYRPSSMGN  360
AKGEQNMLIT DDECCRFLFS EAMSDECFSS GGVNNVDLSG YTSSLCHSSL PSDSRMIMST  420
AEANQLVGSV DQQFDSREDV VKDDSLKLEP VSNSGCGSDT MQTCYPIDEK PNVHTQQEET  480
GGTLCYEPPR FPSLDIPFLS CDLIQSGDMQ QEFSPLGIRQ FMMSSMNCLT PFRLWDSPSR  540
IDSPDALLKS AAKTFTSTPS IMKKKKRNRE RDLLSPLSDR RMEKKHEIDM TSTLIRNFSR  600
LDVMFDDNET QGIEHDKENR GPAFMVEDKS NSEEKIEQPP LDADSKMKND IDTTAEIVQQ  660
PSRVLIEHDM NDPSLYSPNQ VGLKSDIVLS LSARSHQKSV SRFSSPCVRL KEHERLSVSV  720
TCVQSICSSS IPGENMDDQT GNDDGFETNN IFGGMPFRKS FESPSAWKSP LFINTFLSSP  780
RIDAEITIED YGCFFSPGDK SSYDALGWIK QIGEHTAAQY ANALEALENE TPKALPNDAS  840
GDDQENNDPH NQSGNHSKSP SNASVERRML DFSECGTPNK GDKGKSSAMS VSSPSSYLLK  900
GCR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h88_C8e-70331866159MYB PROTO-ONCOGENE PROTEIN
1h89_C8e-70331866159MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Accumulates in the columella root cap. Also present in floral organs in young flower buds. Strongly expressed in vascular tissues of filaments and anthers. Weakly and uniformly present in the developing embryo and maternal tissues (PubMed:17287251). Expressed both in proliferating and maturing stages of leaves (PubMed:26069325). {ECO:0000269|PubMed:17287251, ECO:0000269|PubMed:26069325}.
UniprotTISSUE SPECIFICITY: Expressed ubiquitously at low levels (PubMed:10743663). Expressed in roots, cotyledons, flowers and leaves, especially in vascular tissues (PubMed:17287251). {ECO:0000269|PubMed:10743663, ECO:0000269|PubMed:17287251}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Transcription activator involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269|PubMed:17287251, ECO:0000269|PubMed:21862669, ECO:0000269|PubMed:26069325}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr3g110028.2
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Constant levels during cell cycle. Activated by CYCB1. {ECO:0000269|PubMed:17287251}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013461972.10.0transcription factor MYB3R-1
RefseqXP_024635648.10.0transcription factor MYB3R-1
SwissprotQ9S7G71e-131MB3R1_ARATH; Transcription factor MYB3R-1
TrEMBLA0A072V2D40.0A0A072V2D4_MEDTR; Putative transcription factor MYB-HB-like family
STRINGAES836070.0(Medicago truncatula)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G32730.11e-132Homeodomain-like protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]