PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr2g094520.1
Common NameMTR_2g094520
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family HD-ZIP
Protein Properties Length: 840aa    MW: 91419 Da    PI: 6.3681
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr2g094520.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox56.93.4e-182381357
                     --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
         Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                     k  ++t+eq+e+Le+++ ++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  Medtr2g094520.1 23 KYVRYTAEQIEALEKVYVECPKPSSLRRQQLIRECpvlaNIEPKQIKVWFQNRRCREKQ 81
                     56789****************************************************97 PP
2START147.31.4e-461643692202
                      HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEE CS
            START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galql 93 
                      +aee+++e+++ka+ ++  Wv+++ +++g++++ +f+ s++ +g a+ra+g+v  ++++ ve+l d++  W +++++ e+      g  g+++l
  Medtr2g094520.1 164 IAEETLTEFLSKATGTAVDWVQMPGMKPGPDSVGIFAISQGGNGVAARACGLVSLEPTKIVEILKDRP-TWYRDCRSSEVFTMFPAGngGTIEL 256
                      789*******************************************************9999999999.**********9999999999***** PP

                      EEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHH CS
            START  94 mvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrs 183
                       +++++a+ +l++ Rdf+++Ry+  l+ g+ v++++S++ +   p+    s++ Rae+lpSg+li+p+++g+s +++v+h +l++++++++lr+
  Medtr2g094520.1 257 VYTQTYAPMTLASaRDFWTLRYTTNLENGSVVVCERSLSGTGAGPNaaaASQFERAEMLPSGYLIRPCEGGGSIIHIVDHLNLQAWSVPEVLRP 350
                      *******9999999*****************************9999999******************************************** PP

                      HHHHHHHHHHHHHHHHTXX CS
            START 184 lvksglaegaktwvatlqr 202
                      +++s+++ +++ + a+l++
  Medtr2g094520.1 351 IYESSQMVAQRLTIAALRY 369
                      ***************9987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.3051882IPR001356Homeobox domain
SMARTSM003897.9E-152086IPR001356Homeobox domain
SuperFamilySSF466891.15E-162087IPR009057Homeodomain-like
CDDcd000865.67E-162383No hitNo description
PfamPF000468.1E-162481IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.608.9E-182578IPR009057Homeodomain-like
CDDcd146865.67E-775114No hitNo description
Gene3DG3DSA:1.20.5.1705.2E-479127No hitNo description
PROSITE profilePS5084825.976154382IPR002913START domain
CDDcd088755.33E-66158372No hitNo description
SMARTSM002349.7E-36163373IPR002913START domain
SuperFamilySSF559615.08E-34163373No hitNo description
Gene3DG3DSA:3.30.530.203.7E-21163349IPR023393START-like domain
PfamPF018527.6E-44164370IPR002913START domain
PfamPF086701.6E-50696838IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 840 aa     Download sequence    Send to blast
MAMAVAQQQR DNSIERHLDS SGKYVRYTAE QIEALEKVYV ECPKPSSLRR QQLIRECPVL  60
ANIEPKQIKV WFQNRRCREK QRKEASQLQS VNRKLSAMNK LLMEENERLQ KQVSQLVNEN  120
GFMRQQLHPT PAAPNADGSG VDSAAAAPMN SLRDANSPAG FLSIAEETLT EFLSKATGTA  180
VDWVQMPGMK PGPDSVGIFA ISQGGNGVAA RACGLVSLEP TKIVEILKDR PTWYRDCRSS  240
EVFTMFPAGN GGTIELVYTQ TYAPMTLASA RDFWTLRYTT NLENGSVVVC ERSLSGTGAG  300
PNAAAASQFE RAEMLPSGYL IRPCEGGGSI IHIVDHLNLQ AWSVPEVLRP IYESSQMVAQ  360
RLTIAALRYI RQVAQETSGD VVYSMGRQPA VLRTFSQRLS RGFNDAVNGF NDNGWSVLNC  420
DGAEGVTISV NSIKNLSGTS NPASSLSLLG GIVCAKASML LQNTTPAVLV RFLREHRSEW  480
ADFSVDAFSA ASLKAGSYGY PGMRSTKFTG NQAIMPLGHT IEHEEMLEII RLEGLAQDDS  540
FVSRDVHLLQ LCTGIDENAV GACSELIFAP IDDMFPEDAP LVPSGFRIVL LNSQPGDTKN  600
TTTANRTLDL TSGLEVSPAT AHANGDASCP NNRCVLTVAF QFPFESGLQD NVAAMARQYV  660
RRVVSAVQAV ATAISPSSVN TSGGAKLSPG TPEALTLAQW ICQSYSHHLG AQLLRSDSLI  720
GDMLLKHLWH HPDAILCCSL KQVPVFIFAN QAGLDMLETT LVALQDITLD KIFDESARKN  780
LIAYFAKLMQ QGFACMPAGI CMSTMGRHAS YDQAVAWKVH AEDNSVHCLA FSFINWSFI*
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed at the earliest stages and throughout LSM initiation and development. In embryo development, expressed at the heart stage until the 'walking stick' stage in the adaxial portion of the cotyledon primordia, the shoot apical meristem (SAM) and the vascular precursor cells of the hypocotyl and root. In developing flowers, expressed first at stage 1 in the center of L3 layer and then expands to the center of L2 and L1 layers. Expressed in the center of flower meristem through stages 4 and 5. At stage 6, expressed in the adaxial side of the carpel primordia and then on the adaxial carpel face. {ECO:0000269|PubMed:11169198}.
UniprotTISSUE SPECIFICITY: Expressed in the interfascicular regions of stem and vascular bundles of young roots and leaves. {ECO:0000269|PubMed:10559440}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr2g094520.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003597252.10.0homeobox-leucine zipper protein REVOLUTA
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLG7IRT70.0G7IRT7_MEDTR; Class III homeodomain leucine zipper protein
STRINGAES675030.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF66333147
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  5. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  6. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  7. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]