PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.18G098700.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family WRKY
Protein Properties Length: 575aa    MW: 62935.8 Da    PI: 7.0367
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.18G098700.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY105.23.4e-33238295260
                          --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS-- CS
                 WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhek 60 
                          +DgynWrKYGqK+vkgse+prsYY+Ct+++Cp+kkkvers  d++++ei+Y+g+Hnh+k
  Manes.18G098700.1.p 238 EDGYNWRKYGQKQVKGSENPRSYYKCTYPNCPTKKKVERSL-DGQITEIVYKGSHNHPK 295
                          7****************************************.***************85 PP
2WRKY106.11.8e-33412470159
                          ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                 WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                          ldDgy+WrKYGqK+vkg+++prsYY+Ct+++Cpv+k+ver+++d ++v++tYeg+Hnh+
  Manes.18G098700.1.p 412 LDDGYRWRKYGQKVVKGNPNPRSYYKCTHPSCPVRKHVERASHDFRAVITTYEGKHNHD 470
                          59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.6E-28225296IPR003657WRKY domain
PROSITE profilePS5081123.56232296IPR003657WRKY domain
SuperFamilySSF1182902.62E-25232296IPR003657WRKY domain
SMARTSM007742.4E-36237295IPR003657WRKY domain
PfamPF031061.7E-25238294IPR003657WRKY domain
Gene3DG3DSA:2.20.25.804.6E-37397472IPR003657WRKY domain
SuperFamilySSF1182902.75E-29404472IPR003657WRKY domain
PROSITE profilePS5081137.298407472IPR003657WRKY domain
SMARTSM007741.1E-38412471IPR003657WRKY domain
PfamPF031062.2E-25413470IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009788Biological Processnegative regulation of abscisic acid-activated signaling pathway
GO:0009938Biological Processnegative regulation of gibberellic acid mediated signaling pathway
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 575 aa     Download sequence    Send to blast
MAFSSGSLDT SANSHHSSNF SFSTYSFMST SFSDLLASGA GDEALNTQSE NQRRGLSDRI  60
AERTGSGVPK FKSIPPPSLP ISPPSVSPSS YFAIPPGLSP TELLDSPVLL NSSNILPSPT  120
TGTFPAQAAK WSTSSGRNQQ NVKQEDPNFS DFSFQPPTRP PTASSAMFQS SNTRIQTAQQ  180
QGWSFQESVK QDDFAAGKSM QSFSPEIAAI QTNDGLQSDY GGAHQQQYQS VREQRRSEDG  240
YNWRKYGQKQ VKGSENPRSY YKCTYPNCPT KKKVERSLDG QITEIVYKGS HNHPKPQSTR  300
RSSSSSSAAA ASNHAIIAPN LPSNEMQDQS LVTHGSGQLD VATPENSSIS IGDDDFDSQK  360
SKSRSDEFDE DEPEAKRWKA EGENNEGISG GGSRTVREPR VVVQTTSDID ILDDGYRWRK  420
YGQKVVKGNP NPRSYYKCTH PSCPVRKHVE RASHDFRAVI TTYEGKHNHD VPAARGSGNS  480
VNRALPETNS AAMPMTIRPS AMNHNSLRHL KLPPKTSEGE APFSLEMFQN SDSFAFSGFG  540
NQLGSYTNQT SSDNAFSRAK EEPRDELFLE SLLC*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A5e-33221473178Probable WRKY transcription factor 4
2lex_A5e-33221473178Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator (PubMed:26025535). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:19199048, PubMed:26025535). Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (PubMed:15618416, PubMed:19199048, PubMed:26025535). {ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048, ECO:0000269|PubMed:26025535}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.18G098700.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:15618416, PubMed:19199048). Slightly down-regulated by gibberellic acid (GA) (PubMed:15618416). Accumulates in response to jasmonic acid (MeJA) (By similarity). {ECO:0000250|UniProtKB:Q6B6R4, ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKT8276520.0KT827652.1 Manihot esculenta WRKY transcription factor 77 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021601187.10.0WRKY transcription factor WRKY24-like
SwissprotQ6IEQ71e-131WRK24_ORYSJ; WRKY transcription factor WRKY24
TrEMBLA0A140H8T10.0A0A140H8T1_MANES; WRKY transcription factor 77
STRINGcassava4.1_004465m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF107734114
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G38470.11e-112WRKY DNA-binding protein 33
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Zhang ZL, et al.
    A negative regulator encoded by a rice WRKY gene represses both abscisic acid and gibberellins signaling in aleurone cells.
    Plant Mol. Biol., 2009. 70(1-2): p. 139-51
    [PMID:19199048]
  3. Basu S,Roychoudhury A
    Expression profiling of abiotic stress-inducible genes in response to multiple stresses in rice (Oryza sativa L.) varieties with contrasting level of stress tolerance.
    Biomed Res Int, 2014. 2014: p. 706890
    [PMID:25110688]
  4. Zhang L, et al.
    Three WRKY transcription factors additively repress abscisic acid and gibberellin signaling in aleurone cells.
    Plant Sci., 2015. 236: p. 214-22
    [PMID:26025535]
  5. Wei Y, et al.
    Genome-Wide Identification and Expression Analysis of the WRKY Gene Family in Cassava.
    Front Plant Sci, 2016. 7: p. 25
    [PMID:26904033]