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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
Manes.18G072700.2.p |
| Organism |
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| Taxonomic ID |
|
| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
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| Family |
C2H2 |
| Protein Properties |
Length: 311aa MW: 36296.9 Da PI: 7.9491 |
| Description |
C2H2 family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| Manes.18G072700.2.p | genome | JGI | View CDS |
|
| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | zf-C2H2 | 12.5 | 0.00044 | 68 | 90 | 1 | 23 |
EEETTTTEEESSHHHHHHHHHHT CS
zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23
y C+ C +rk++L+rH+r++
Manes.18G072700.2.p 68 YFCEFCLNFMKRKEQLQRHMRKC 90
78*******************98 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006281 | Biological Process | DNA repair |
| GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
| GO:0010224 | Biological Process | response to UV-B |
| GO:2000028 | Biological Process | regulation of photoperiodism, flowering |
| GO:0005634 | Cellular Component | nucleus |
| GO:0043995 | Molecular Function | histone acetyltransferase activity (H4-K5 specific) |
| Sequence ? help Back to Top |
| Protein Sequence Length: 311 aa
Download sequence Send
to blast |
MVVFEFYTRK LSFYNLQGHE ELDAASLREH EEFTKVKNIA TIELGRYEIE TWYFSPFPPE 60
YNDSVKLYFC EFCLNFMKRK EQLQRHMRKC DLKHPPGDEI YRSGTLSMFE VDGKKNKVYG 120
QNLCYLAKLF LDHKTLYYDV DLFLFYILCE CDDRGCHMVG YFSKEKHSEE SYNLACILTL 180
PPYQRKGYGK FLIAFSYELS KKEGKVGTPE RPLSDLGLLS YRGYWTRVLL DILKKHKGNI 240
SIKELSDMTA IKAEDILTTL QSLELIQYRK GQHVICADPK VLDRHLKAAG RGGLEVDVSK 300
LIWTPYKEQG *
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| Functional Description ? help
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| Source |
Description |
| UniProt | Histone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}. |
| UniProt | Histone acetyltransferase which may be involved in transcriptional activation. {ECO:0000250|UniProtKB:Q9LXD7}. |
| Regulation -- Description ? help
Back to Top |
| Source |
Description |
| UniProt | INDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}. |
| Publications
? help Back to Top |
- Latrasse D, et al.
The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
BMC Plant Biol., 2008. 8: p. 121
[PMID:19040736] - Campi M,D'Andrea L,Emiliani J,Casati P
Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
Plant Physiol., 2012. 158(2): p. 981-95
[PMID:22170978] - Bari A,Orazova S,Ivashchenko A
miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
Biomed Res Int, 2013. 2013: p. 307145
[PMID:23936788] - Xu Y, et al.
Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
Nucleic Acids Res., 2014. 42(17): p. 10960-74
[PMID:25183522] - Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
J Mol Model, 2016. 22(11): p. 256
[PMID:27709438] - Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
Front Plant Sci, 2017. 8: p. 1179
[PMID:28740501]
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