PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot

Family

C2H2

Protein Properties

Length: 567aa MW: 60992.8 Da PI: 9.7767

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Manes.17G092200.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.2	2.9e-05	66	88	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C+ C+k F r nL+ H r H Manes.17G092200.1.p 66 FICEVCNKGFQREQNLQLHRRGH 88 89*******************88 PP
2	zf-C2H2	12.5	0.00043	142	164	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k + +s+ k H +t+ Manes.17G092200.1.p 142 WKCEKCSKKYAVQSDWKAHSKTC 164 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	5.38E-7	65	88	No hit	No description
Gene3D	G3DSA:3.30.160.60	6.3E-6	65	88	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.0052	66	88	IPR015880	Zinc finger, C2H2-like
Pfam	PF12171	2.8E-5	66	88	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE profile	PS50157	10.99	66	88	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	68	88	IPR007087	Zinc finger, C2H2
SMART	SM00355	150	107	137	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	7.1E-5	130	163	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	5.38E-7	137	162	No hit	No description
SMART	SM00355	140	142	162	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 567 aa Download sequence Send to blast
MAAASSSVSL FRSREENQNQ MMQQNSSTAA PTTAPQKKKR NQPGTPNPDA EVIALSPKTL 60 MATNRFICEV CNKGFQREQN LQLHRRGHNL PWKLKQKTTK EVKRKVYLCP EPTCVHHDPS 120 RALGDLTGIK KHYFRKHGEK KWKCEKCSKK YAVQSDWKAH SKTCGTREYR CDCGTLFSRR 180 DSFITHRAFC DALAQESARH PTSLSTIGTH LYGNNNMGIG LSQVGSQISS LQDQNHPTSN 240 MLRLGSTGAA KFEHIIPPSN SSSLSTMPSS AFFMSDANQG SFPNKSLHGL MQLPDLQSST 300 DNSSTTNLFN LGFFPSNATA PNRMNDSDNA NSSTVTTNLV NSRFLNSNPF HNGNGGQGTT 360 TLFANNMGDH VGSAGISSLY SNSMQQENIT PHMSATALLQ KASQMGSTTS SNNPNLLRSL 420 GSSPSTGIKS DRSPLVSTNF GSNSFGDATV GEVGLGIQME SDNQLQGLMN SLANGGSSIF 480 GGGHGQDNSF GGFTSGGVSL EQHHNSTKFR NVEEAKLHQS LGVGSDKLTL DFLGVGGMVR 540 SIGGGQHGIN LSSLDSQSAQ ANNKRF*

Sequence ? help Back to Top

Protein Sequence Length: 567 aa Download sequence Send to blast

MAAASSSVSL FRSREENQNQ MMQQNSSTAA PTTAPQKKKR NQPGTPNPDA EVIALSPKTL  60
MATNRFICEV CNKGFQREQN LQLHRRGHNL PWKLKQKTTK EVKRKVYLCP EPTCVHHDPS  120
RALGDLTGIK KHYFRKHGEK KWKCEKCSKK YAVQSDWKAH SKTCGTREYR CDCGTLFSRR  180
DSFITHRAFC DALAQESARH PTSLSTIGTH LYGNNNMGIG LSQVGSQISS LQDQNHPTSN  240
MLRLGSTGAA KFEHIIPPSN SSSLSTMPSS AFFMSDANQG SFPNKSLHGL MQLPDLQSST  300
DNSSTTNLFN LGFFPSNATA PNRMNDSDNA NSSTVTTNLV NSRFLNSNPF HNGNGGQGTT  360
TLFANNMGDH VGSAGISSLY SNSMQQENIT PHMSATALLQ KASQMGSTTS SNNPNLLRSL  420
GSSPSTGIKS DRSPLVSTNF GSNSFGDATV GEVGLGIQME SDNQLQGLMN SLANGGSSIF  480
GGGHGQDNSF GGFTSGGVSL EQHHNSTKFR NVEEAKLHQS LGVGSDKLTL DFLGVGGMVR  540
SIGGGQHGIN LSSLDSQSAQ ANNKRF*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	1e-34	138	199	3	64	Zinc finger protein JACKDAW
5b3h_F	1e-34	138	199	3	64	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor acting as a positive regulator of the starch synthase SS4. Controls chloroplast development and starch granule formation (PubMed:22898356). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). {ECO:0000269\|PubMed:22898356, ECO:0000269\|PubMed:24821766}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00255	DAP	Transfer from AT2G02070	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Manes.17G092200.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC208494	1e-144	AC208494.1 Populus trichocarpa clone JGIACSB265-L05, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021599763.1	0.0	protein indeterminate-domain 5, chloroplastic-like
Swissprot	Q9ZUL3	1e-141	IDD5_ARATH; Protein indeterminate-domain 5, chloroplastic
TrEMBL	A0A2C9U6M2	0.0	A0A2C9U6M2_MANES; Uncharacterized protein
STRING	cassava4.1_004443m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1536	33	97

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G02070.1	1e-124	indeterminate(ID)-domain 5

Link Out ? help Back to Top
Phytozome	Manes.17G092200.1.p

Publications ? help Back to Top
Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]