PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot

Family

C2H2

Protein Properties

Length: 582aa MW: 63523.4 Da PI: 9.2498

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Manes.15G141300.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.2	3e-05	71	93	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C+ C+k F r nL+ H r H Manes.15G141300.1.p 71 FICEVCNKGFQREQNLQLHRRGH 93 89*******************88 PP
2	zf-C2H2	13.1	0.00028	147	169	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k++ +s+ k H +t+ Manes.15G141300.1.p 147 WKCEKCSKRYAVQSDWKAHSKTC 169 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.69E-7	70	93	No hit	No description
Gene3D	G3DSA:3.30.160.60	6.5E-6	70	93	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF12171	2.8E-5	71	93	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE profile	PS50157	10.99	71	93	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0052	71	93	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	73	93	IPR007087	Zinc finger, C2H2
SMART	SM00355	130	112	142	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	2.1E-5	135	168	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.69E-7	142	167	No hit	No description
SMART	SM00355	130	147	167	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 582 aa Download sequence Send to blast
MAASSSSVPF FGIRDEDHQN QMTQQHSSTP TSSSAPAPPP QKKKRNLPRT PNPDAEVIAL 60 SPKTLMATNR FICEVCNKGF QREQNLQLHR RGHNLPWKLK QKTTKEVKRK VYLCPEPTCV 120 HHDPSRALGD LTGIKKHYSR KHGEKKWKCE KCSKRYAVQS DWKAHSKTCG TREYRCDCGT 180 LFSRRDSFIT HRAFCDALAQ ESARNPPSTL STIASHLYGG SNMSLGVSQV GTQISSMQEQ 240 SSDILRLGGG GRSGQFDHLL PPSMGSTSFR QPSQQMPSSA FFMQEPNQNY HEEHQSQQGL 300 LQNKSFHHGL MQFADIHSTT SNNPPPPASN LFNLSFISSS SSTSNIANSN LPPSGLLLST 360 HFNGHNGASG DGEGSNIFTN NIISDYHHHH HQMTSGVPSL FSSSVQNDKM FPHMSATALL 420 QKAAQMGSTT STNSASLLRS FGSSSSSGIK SNRQLGAANF GGVFNENDNN LHDLMNSFAT 480 GNSSLFASGH GQENSYSGNP EEPKLHQGLN MSIGGSDRLT RDFLGVGQIV RSMSGGFSQR 540 EKHQQLQQPP QPGIEMSSSL DSERNITAQT SQSFGGIGDF Q*

Sequence ? help Back to Top

Protein Sequence Length: 582 aa Download sequence Send to blast

MAASSSSVPF FGIRDEDHQN QMTQQHSSTP TSSSAPAPPP QKKKRNLPRT PNPDAEVIAL  60
SPKTLMATNR FICEVCNKGF QREQNLQLHR RGHNLPWKLK QKTTKEVKRK VYLCPEPTCV  120
HHDPSRALGD LTGIKKHYSR KHGEKKWKCE KCSKRYAVQS DWKAHSKTCG TREYRCDCGT  180
LFSRRDSFIT HRAFCDALAQ ESARNPPSTL STIASHLYGG SNMSLGVSQV GTQISSMQEQ  240
SSDILRLGGG GRSGQFDHLL PPSMGSTSFR QPSQQMPSSA FFMQEPNQNY HEEHQSQQGL  300
LQNKSFHHGL MQFADIHSTT SNNPPPPASN LFNLSFISSS SSTSNIANSN LPPSGLLLST  360
HFNGHNGASG DGEGSNIFTN NIISDYHHHH HQMTSGVPSL FSSSVQNDKM FPHMSATALL  420
QKAAQMGSTT STNSASLLRS FGSSSSSGIK SNRQLGAANF GGVFNENDNN LHDLMNSFAT  480
GNSSLFASGH GQENSYSGNP EEPKLHQGLN MSIGGSDRLT RDFLGVGQIV RSMSGGFSQR  540
EKHQQLQQPP QPGIEMSSSL DSERNITAQT SQSFGGIGDF Q*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	1e-34	143	204	3	64	Zinc finger protein JACKDAW
5b3h_F	1e-34	143	204	3	64	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor acting as a positive regulator of the starch synthase SS4. Controls chloroplast development and starch granule formation (PubMed:22898356). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). {ECO:0000269\|PubMed:22898356, ECO:0000269\|PubMed:24821766}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Manes.15G141300.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC208494	1e-160	AC208494.1 Populus trichocarpa clone JGIACSB265-L05, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021593421.1	0.0	protein indeterminate-domain 5, chloroplastic-like
Swissprot	Q9ZUL3	1e-152	IDD5_ARATH; Protein indeterminate-domain 5, chloroplastic
TrEMBL	A0A2C9UHR4	0.0	A0A2C9UHR4_MANES; Uncharacterized protein
STRING	cassava4.1_005672m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1536	33	97

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G02070.1	1e-143	indeterminate(ID)-domain 5

Link Out ? help Back to Top
Phytozome	Manes.15G141300.1.p

Publications ? help Back to Top
Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]