PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.11G146000.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family HD-ZIP
Protein Properties Length: 843aa    MW: 91860.6 Da    PI: 6.2666
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.11G146000.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox57.32.6e-182583357
                         --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
             Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                         k  ++t+eq+e+Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  Manes.11G146000.1.p 25 KYVRYTAEQVEALERVYAECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 83
                         5679*****************************************************97 PP
2START161.18.1e-511633702204
                          HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..E CS
                START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..g 89 
                          +aee+++e+++ka+ ++  Wv+++ +++g++++ +f+ s+++sg a+ra+g+v  +++   +e+l+d++ W +++++ e+      g  g
  Manes.11G146000.1.p 163 IAEETLAEFLSKATGTAVDWVQMPGMKPGPDSVGIFAISQSCSGVAARACGLVSLEPT-KIAEILKDRPSWFRDCRSLEVFTMFPAGngG 251
                          7899******************************************************.7777777777***********999999999* PP

                          EEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SS CS
                START  90 alqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgr 175
                          +++l +++ +a+++l+p Rdf+++Ry+ +l+ g++v++++S++     p+    s++vRae+lpSg+li+p+++g+s +++v+h +l+ +
  Manes.11G146000.1.p 252 TIELVYSQIYAPTTLAPaRDFWTLRYTTSLENGSLVVCERSLSGSGAGPNaaaASQFVRAEMLPSGYLIRPCEGGGSIIHIVDHLNLEPW 341
                          *******************************************99999999999************************************ PP

                          XXHHHHHHHHHHHHHHHHHHHHHHTXXXX CS
                START 176 lphwllrslvksglaegaktwvatlqrqc 204
                          +++++lr+l++s+ + ++kt+ a+l++ +
  Manes.11G146000.1.p 342 SVPEVLRPLYESSKVVAQKTTIAALRYIR 370
                          ************************99865 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.372084IPR001356Homeobox domain
SMARTSM003893.8E-152288IPR001356Homeobox domain
SuperFamilySSF466892.82E-162387IPR009057Homeodomain-like
CDDcd000864.79E-162585No hitNo description
PfamPF000467.5E-162683IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.602.9E-182783IPR009057Homeodomain-like
CDDcd146861.78E-677116No hitNo description
PROSITE profilePS5084826.882153381IPR002913START domain
CDDcd088752.56E-72157373No hitNo description
Gene3DG3DSA:3.30.530.203.8E-19162352IPR023393START-like domain
SMARTSM002344.9E-41162372IPR002913START domain
SuperFamilySSF559613.71E-34162374No hitNo description
PfamPF018522.4E-48163370IPR002913START domain
PfamPF086706.1E-50698841IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0009956Biological Processradial pattern formation
GO:0010014Biological Processmeristem initiation
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010089Biological Processxylem development
GO:0030154Biological Processcell differentiation
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 843 aa     Download sequence    Send to blast
MAMAVAQHRE SSSGSINKHL TDNGKYVRYT AEQVEALERV YAECPKPSSL RRQQLIRECP  60
ILSNIEPKQI KVWFQNRRCR EKQRKEASRL QTVNRKLTAM NKLLMEENDR LQKQVSQLVC  120
ENGYMRQQLH TASAGTDASC DSVVTTPQHS LRDASNPAGL LSIAEETLAE FLSKATGTAV  180
DWVQMPGMKP GPDSVGIFAI SQSCSGVAAR ACGLVSLEPT KIAEILKDRP SWFRDCRSLE  240
VFTMFPAGNG GTIELVYSQI YAPTTLAPAR DFWTLRYTTS LENGSLVVCE RSLSGSGAGP  300
NAAAASQFVR AEMLPSGYLI RPCEGGGSII HIVDHLNLEP WSVPEVLRPL YESSKVVAQK  360
TTIAALRYIR QIAQETSGEV VYGLGRQPAV LRTFSQRLSR GFNDAINGFN DDGWSLMSCD  420
GAEDVIIAVN STKNLSSTSN PANSLSFLGG VLCAKASMLL QNVPPAVLVR FLREHRSEWA  480
DFNVDAYSAA SLKAGSYAFP GMRPARFTGS QIIMPLGHTI EHEELLEVIR LEGHSLVQED  540
AFVSRDIHLL QICSGIDENA VGACSELVFA PIDEMFPDDA PLLPSGFRVI PLDSKTKDAP  600
DAVNASRTLD LTSSLEVGPA TNHVAGDASS SHSTRSVLTI AFQFPFESNL QDNVSTMARQ  660
YVRSVISAVQ RVAMAISPSE LSPAVGPKLS PGSPEALTLA HWICQSYSYY LGAELLRSDS  720
LGGDSVLKHL WHHQDAILCC SLKSLPVFIF ANQAGLDMLE TTLVALQDIT LDKIFDESGR  780
KALCADFAKL MQQGFAHLPG GICMSTMGRH VSYEQAVAWK VLAADENSVH CLAFSFVNWS  840
FV*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.11G146000.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021628343.10.0homeobox-leucine zipper protein REVOLUTA-like
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLA0A2C9V1G80.0A0A2C9V1G8_MANES; Uncharacterized protein
STRINGcassava4.1_001649m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF66333147
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]