PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot

Family

MYB

Protein Properties

Length: 427aa MW: 48463.2 Da PI: 7.3745

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Manes.06G105800.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	56.2	8e-18	180	226	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT eEd ll ++v+q+G + W+ Ia++++ gR +kqc++rw+++l Manes.06G105800.1.p 180 KGQWTIEEDRLLTQLVEQYGVRKWSHIAQMLP-GRIGKQCRERWHNHL 226 799***************************.***********97 PP
2	Myb_DNA-binding	54.6	2.5e-17	233	274	2	45
SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS Myb_DNA-binding 2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 + W+++Ed++l++a+++ G++ W+ Ia++++ gRt++++k++w+ Manes.06G105800.1.p 233 DMWSEDEDKILIHAHAEIGNK-WAEIAKRLP-GRTENSIKNHWN 274 67*****************.*****.*********8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	29.822	175	230	IPR017930	Myb domain
SuperFamily	SSF46689	1.37E-31	177	273	IPR009057	Homeodomain-like
SMART	SM00717	2.7E-16	179	228	IPR001005	SANT/Myb domain
Pfam	PF00249	9.9E-17	180	226	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	5.1E-28	181	233	IPR009057	Homeodomain-like
CDD	cd00167	1.01E-15	183	226	No hit	No description
PROSITE profile	PS51294	20.488	231	281	IPR017930	Myb domain
SMART	SM00717	2.3E-15	231	279	IPR001005	SANT/Myb domain
Pfam	PF00249	2.5E-16	233	274	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	6.2E-22	234	279	IPR009057	Homeodomain-like
CDD	cd00167	2.82E-13	235	277	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 427 aa Download sequence Send to blast
MSDYFSDKPS MKYGSPFEAP PSSPSKGFSQ DLHHFDQFHA NGLSLNPIFG AQNASNFDFF 60 DALPYGSSTN IDFSDYECKP FADNNGGHGQ VMDNFQNGGF LNLPHNQSNS IGTMMGSNQG 120 QGNMSLGFQE MKPINFVVPD EVSCINANQE YHKKVGVDKN RASSSMGRTW RGRKKNNVVK 180 GQWTIEEDRL LTQLVEQYGV RKWSHIAQML PGRIGKQCRE RWHNHLRPDI KKDMWSEDED 240 KILIHAHAEI GNKWAEIAKR LPGRTENSIK NHWNATKRRQ YSKRRCRSKY PKGSLLQEYI 300 KSLNLGSVPA AAGRFLGKSS DARAVNNISM KAPNLQPQVS EISQNNNRLF PNYYDFNEVP 360 AFDFDERMIQ EGCSFGSFLD EMANGDRGFD EKSFEMNVAM EEVSPFMDFG EKKELDLVEM 420 ISQARM*

Sequence ? help Back to Top

Protein Sequence Length: 427 aa Download sequence Send to blast

MSDYFSDKPS MKYGSPFEAP PSSPSKGFSQ DLHHFDQFHA NGLSLNPIFG AQNASNFDFF  60
DALPYGSSTN IDFSDYECKP FADNNGGHGQ VMDNFQNGGF LNLPHNQSNS IGTMMGSNQG  120
QGNMSLGFQE MKPINFVVPD EVSCINANQE YHKKVGVDKN RASSSMGRTW RGRKKNNVVK  180
GQWTIEEDRL LTQLVEQYGV RKWSHIAQML PGRIGKQCRE RWHNHLRPDI KKDMWSEDED  240
KILIHAHAEI GNKWAEIAKR LPGRTENSIK NHWNATKRRQ YSKRRCRSKY PKGSLLQEYI  300
KSLNLGSVPA AAGRFLGKSS DARAVNNISM KAPNLQPQVS EISQNNNRLF PNYYDFNEVP  360
AFDFDERMIQ EGCSFGSFLD EMANGDRGFD EKSFEMNVAM EEVSPFMDFG EKKELDLVEM  420
ISQARM*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gv2_A	4e-44	178	280	2	104	MYB PROTO-ONCOGENE PROTEIN
1mse_C	3e-44	178	280	2	104	C-Myb DNA-Binding Domain
1msf_C	3e-44	178	280	2	104	C-Myb DNA-Binding Domain
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds to the motif 5'-GTAACNT-3' in the promoter of target genes (e.g. DD11 and DD18) and promotes their expression within synergid cells (e.g. in the filiform apparatus) in ovules (PubMed:16214903, PubMed:17693534, PubMed:18410484, PubMed:17937500). Required for the formation of the filiform apparatus during synergid cell differentiation in the female gametophyte (PubMed:16214903). Involved in pollen tube guidance to the micropyle (PubMed:16214903, PubMed:17937500, PubMed:23093426). {ECO:0000269\|PubMed:16214903, ECO:0000269\|PubMed:17693534, ECO:0000269\|PubMed:17937500, ECO:0000269\|PubMed:18410484, ECO:0000269\|PubMed:23093426}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Manes.06G105800.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021616616.1	0.0	transcription factor MYB98-like
Swissprot	Q9S7L2	7e-93	MYB98_ARATH; Transcription factor MYB98
TrEMBL	A0A2C9VPQ5	0.0	A0A2C9VPQ5_MANES; Uncharacterized protein
STRING	cassava4.1_032562m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1570	31	96

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G18770.1	3e-95	myb domain protein 98

Link Out ? help Back to Top
Phytozome	Manes.06G105800.1.p

Publications ? help Back to Top
Mendes MA, et al. Live and let die: a REM complex promotes fertilization through synergid cell death in Arabidopsis. Development, 2016. 143(15): p. 2780-90 [PMID:27338615]