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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
Back to Top |
| TF ID |
Manes.04G088800.1.p |
| Organism |
|
| Taxonomic ID |
|
| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
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| Family |
bHLH |
| Protein Properties |
Length: 393aa MW: 43880 Da PI: 6.52 |
| Description |
bHLH family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| Manes.04G088800.1.p | genome | JGI | View CDS |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | HLH | 30.9 | 5e-10 | 239 | 286 | 4 | 55 |
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55
+h+ +Er RR++i +++ L++l+P + +k Ka +L + ++Y++sLq
Manes.04G088800.1.p 239 SHSLAERVRREKISERMKYLQDLVPGC----NKITGKAGMLDEIINYVQSLQ 286
8**************************....999*****************9 PP
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| Sequence ? help Back to Top |
| Protein Sequence Length: 393 aa
Download sequence Send
to blast |
MNRALLPEML HCTDMTVLER QRARFKWQQE QELQQQQQQH HQQESFFGDL SGVFQLQLQH 60
QGLQGDLGEV VTRSVKPDPA SMDNGWPGLV GFGPSGYENN NGSGFDVNYA ISRTSSCQPA 120
VAGAAVDATV LAESREPVMS EKLSPGVGRE NLKKRKVDKL QHNTKVVAED ESRDKRVKGC 180
AGEGESMNTE KNNNKSSSTS KNSTKENSAE TSKDNSKVTE VQKPDYIHVR ARRGQATDSH 240
SLAERVRREK ISERMKYLQD LVPGCNKITG KAGMLDEIIN YVQSLQRQVE FLSMKLAAVN 300
PRLEFNIDNV FAKEAFPAPT TNFPETGMSS DLTNPVYLQF NQAQQQQQQQ QQQLFSSSGS 360
IPEMFIDPSC FTHIQPSSTW DAVSDLQKIF TM*
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| Functional Description ? help
Back to Top |
| Source |
Description |
| UniProt | Transcription factor that binds DNA to G box 5'-CACGTG-3' and, to a lower extent, to E-box 5'-CANNTG-3' in vitro. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light. {ECO:0000269|PubMed:18988809, ECO:0000269|PubMed:24130508}. |
| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Accumulates strongly in response to blue light due to reduced preventing 26S proteasome-mediated degradation in an ADO1/ZTL and ADO2/LKP2 dependent manner, but levels decrease in the absence of blue light via 26S proteasome degradation (at protein level). {ECO:0000269|PubMed:24101505}. |
| Best hit in Arabidopsis thaliana ? help
Back to Top |
| Hit ID |
E-value |
Description |
| AT4G34530.1 | 2e-60 | cryptochrome-interacting basic-helix-loop-helix 1 |
| Publications
? help Back to Top |
- Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
Differentiation, 2010. 80(1): p. 1-8
[PMID:20219281] - Yang D,Zhao W,Meng Y,Li H,Liu B
A CIB1-LIKE transcription factor GmCIL10 from soybean positively regulates plant flowering.
Sci China Life Sci, 2015. 58(3): p. 261-9
[PMID:25651969] - Katsura Y, et al.
An optogenetic system for interrogating the temporal dynamics of Akt.
Sci Rep, 2015. 5: p. 14589
[PMID:26423353] - Taslimi A, et al.
Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase.
Nat. Chem. Biol., 2016. 12(6): p. 425-30
[PMID:27065233] - Liu Q, et al.
The Blue Light-Dependent Polyubiquitination and Degradation of Arabidopsis Cryptochrome2 Requires Multiple E3 Ubiquitin Ligases.
Plant Cell Physiol., 2016. 57(10): p. 2175-2186
[PMID:27516416] - Pathak GP, et al.
Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2.
Nucleic Acids Res., 2017. 45(20): p. e167
[PMID:28431041] - Duan L, et al.
Understanding CRY2 interactions for optical control of intracellular signaling.
Nat Commun, 2017. 8(1): p. 547
[PMID:28916751] - Quejada JR, et al.
Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1.
Nucleic Acids Res., 2017. 45(20): p. e172
[PMID:29040770] - Liu Y, et al.
CIB1 and CO interact to mediate CRY2-dependent regulation of flowering.
EMBO Rep., 2019.
[PMID:30126927]
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