PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.04G020100.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family HD-ZIP
Protein Properties Length: 842aa    MW: 92020.8 Da    PI: 6.1488
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.04G020100.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox56.45.1e-182583357
                         --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
             Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                         k  ++t+eq+++Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  Manes.04G020100.1.p 25 KYVRYTAEQVDALERVYAECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 83
                         56789****************************************************97 PP
2START157.11.4e-491623692204
                          HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..E CS
                START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..g 89 
                          +aee+++e+++ka+ ++  Wv+++ +++g++++ +f+ s+++sg a+ra+g+v  +++   +e+l+d++ W +++++ e+      g  g
  Manes.04G020100.1.p 162 IAEETLAEFLSKATGTAVDWVQMPGMKPGPDSVGIFAISQSCSGVAARACGLVSLEPT-KIAEILKDRPSWFRDCRSLEVFTMFPAGngG 250
                          7899******************************************************.7777777777***********999999999* PP

                          EEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SS CS
                START  90 alqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgr 175
                          +++l +++ +a+ +l+p Rdf+++Ry+ +l+ g++v++++S++     p+    s++vRae+lpSg+li+p+++g+s +++v+h +l+++
  Manes.04G020100.1.p 251 TIELVYSQIYAPMTLAPaRDFWTLRYTTSLENGSLVVCERSLSGSGTGPNaaaASQFVRAEMLPSGYLIRPCEGGGSIIHIVDHLNLEAW 340
                          *******************************************98888888999************************************ PP

                          XXHHHHHHHHHHHHHHHHHHHHHHTXXXX CS
                START 176 lphwllrslvksglaegaktwvatlqrqc 204
                          +++++lr+l++s+ + ++k++ a+l++ +
  Manes.04G020100.1.p 341 SVPEVLRPLYESSKVVAQKMTIAALRYIR 369
                          ************************99865 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.1752084IPR001356Homeobox domain
SMARTSM003892.0E-152288IPR001356Homeobox domain
SuperFamilySSF466893.55E-162386IPR009057Homeodomain-like
CDDcd000868.78E-162585No hitNo description
PfamPF000461.6E-152683IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.603.0E-182783IPR009057Homeodomain-like
CDDcd146864.07E-677116No hitNo description
PROSITE profilePS5084827.47152380IPR002913START domain
CDDcd088752.15E-70156372No hitNo description
Gene3DG3DSA:3.30.530.205.4E-20161361IPR023393START-like domain
SuperFamilySSF559611.37E-34161373No hitNo description
SMARTSM002344.3E-42161371IPR002913START domain
PfamPF018523.4E-47162369IPR002913START domain
PfamPF086702.0E-49697840IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 842 aa     Download sequence    Send to blast
MAMALAQHRD SSNGSINKHL TDSGKYVRYT AEQVDALERV YAECPKPSSL RRQQLIRECP  60
ILSNIEPKQI KVWFQNRRCR EKQRNESSRL QTVNRKLTAM NKLLMEENDR LQKQVSQLVC  120
ENGYMRQQLN TASATDASCD SVVTTPQHSL RDANNPAGLL SIAEETLAEF LSKATGTAVD  180
WVQMPGMKPG PDSVGIFAIS QSCSGVAARA CGLVSLEPTK IAEILKDRPS WFRDCRSLEV  240
FTMFPAGNGG TIELVYSQIY APMTLAPARD FWTLRYTTSL ENGSLVVCER SLSGSGTGPN  300
AAAASQFVRA EMLPSGYLIR PCEGGGSIIH IVDHLNLEAW SVPEVLRPLY ESSKVVAQKM  360
TIAALRYIRQ IAQETSGEVV YGLGRQPAVL RTFSQKLSRG FNDAVNGFND DGWSLMSCDG  420
AEDVIIAVNS TKNLSSTSNT SNSLSFLGGI LCAKASMLLQ NVPPAVLVRF LREHRSEWAD  480
FNVDAYSAVS LKAGSYVFPG MRATRFTGSQ IIMPLGHTIE HEELLEVVRL EGHSLAQEDA  540
FISRDIHLLQ ICSGIDENAV GACAELVFAP IDEMFPDDAP LLPSGFRVIP LDSKTKDAQT  600
AVNTSRTLDL TTSLEVGPAT NHATEDASSS HSTRSVLTIA FQFPFESNLQ DNVANMARQY  660
VRSVISSVQR VAMAISPSGL SPSVGPKLSP SSPEALTLAH WICQSYSYYL GAELLRSDSL  720
GGDSVLKHLW HHQDAILCCS LKSLPVFIFA NQAGMDMLET TLVALQDITL DKIFDESGRK  780
ALCADFAKLM QQGFAYLPGG ICMSTMGRHV SYEQAVAWKV LAADESTVHC LAFSFVNWSF  840
V*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.04G020100.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021610391.10.0homeobox-leucine zipper protein REVOLUTA-like
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLA0A2C9W0660.0A0A2C9W066_MANES; Uncharacterized protein
STRINGcassava4.1_001653m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF66333147
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]