PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.02G225800.2.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family HSF
Protein Properties Length: 521aa    MW: 56285.6 Da    PI: 4.5921
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.02G225800.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind115.82.6e-36461372102
                          HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXX CS
         HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkk 91 
                          Fl+k+y++++d++++ ++sws+++nsfvv+++ efa+++LpkyFkh+nf+SFvRQLn+YgF+kv+ ++         weF+++ F +g+k
  Manes.02G225800.2.p  46 FLSKTYDMVDDPATDGIVSWSSTNNSFVVWNPPEFARDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQK 126
                          9****************************************************************999.........************* PP

                          XXXXXXXXXXX CS
         HSF_DNA-bind  92 ellekikrkks 102
                          +ll++i r+k 
  Manes.02G225800.2.p 127 HLLKSISRRKP 137
                          ********986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.6E-4038130IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467856.26E-3642135IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004152.6E-6342135IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004473.1E-3246135IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000564.8E-204669IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000564.8E-208496IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS00434085109IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000564.8E-2097109IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 521 aa     Download sequence    Send to blast
MEGVISNGGG GGGSGDASTS GSGSGGAQPP AAPVPISTQS NAPPPFLSKT YDMVDDPATD  60
GIVSWSSTNN SFVVWNPPEF ARDLLPKYFK HNNFSSFVRQ LNTYGFRKVD PDRWEFANEG  120
FLRGQKHLLK SISRRKPAHG HAHQQTPQPH GQSSSVGACV EVGKFGLEEE VERLKRDKNV  180
LMQELVRLRQ QQQATDGQLQ TMVQRLQGME QRQQQMMSFL AKAMQSPGFL SQFVQQQNES  240
NRRITEANKK RRIKQDGISE NENPSVPDGQ IVKYQPMMNE AAQAMLRQIM KTDPSSGVES  300
YNSGLEDFLM GSGSPSSSGM ESGSSSTRIS GVTLQEVPPT TGHSTYVPAV SGLSGHDPAA  360
SIPEIKPAPC IPSSGNITAQ YPDISALVGS QEAPSISIPQ SDVVMPTLDH IPEIVPESIV  420
DIPGEGYMVP ETGNDGFMDL TSIGIGNVSP DPDIDILLEN SSFWDELVQS PVPEDIESTS  480
MDGQTKGNDV QPVENGWDKT QHMDQLTEQM GLLTSDAKKL *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B3e-27171352129Heat shock factor protein 1
5d5v_B3e-27171352129Heat shock factor protein 1
5d5v_D3e-27171352129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1247254NKKRRIKQ
2248253KKRRIK
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.02G225800.2.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021604617.10.0heat shock factor protein HSF8 isoform X1
SwissprotQ401520.0HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBLA0A251LLT00.0A0A251LLT0_MANES; Uncharacterized protein
STRINGcassava4.1_005587m0.0(Manihot esculenta)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32330.11e-145heat shock transcription factor A1D
Publications ? help Back to Top
  1. Zhu B, et al.
    Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max).
    J. Plant Res., 2006. 119(3): p. 247-56
    [PMID:16570125]
  2. Cai SY, et al.
    HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants.
    J. Pineal Res., 2017.
    [PMID:28095626]
  3. Zhou J, et al.
    Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1.
    Plant Physiol., 2018. 176(3): p. 2456-2471
    [PMID:29339397]