PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot

Family

ERF

Protein Properties

Length: 296aa MW: 33801.4 Da PI: 4.8288

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Manes.01G249600.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	60.7	3.3e-19	105	155	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.psengkr.krfslgkfgtaeeAakaaiaarkkleg 55 ++y+GVr+++ +gr++AeIrd + r +r++lg+f+taeeAa +++a+ k++g Manes.01G249600.1.p 105 KKYRGVRQRP-WGRFAAEIRDpF-----RrTRVWLGTFDTAEEAAIVYDNAAIKIKG 155 59******.******66.....45**********************988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	1.05E-32	105	162	No hit	No description
Gene3D	G3DSA:3.30.730.10	1.8E-29	106	163	IPR001471	AP2/ERF domain
Pfam	PF00847	3.4E-12	106	155	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	9.15E-21	106	162	IPR016177	DNA-binding domain
PROSITE profile	PS51032	22.55	106	163	IPR001471	AP2/ERF domain
SMART	SM00380	3.8E-37	106	169	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.8E-10	107	118	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.8E-10	129	145	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 296 aa Download sequence Send to blast
MISSSSVKYS EHKTVTDKIA KCNDSNSTRV VRIYVTDGDA TDSSSDENEN PILGHQRIKK 60 HINEVRIKDC VECSNGRAHE CSKSRPNKQP LRKSTRDQLY YPESKKYRGV RQRPWGRFAA 120 EIRDPFRRTR VWLGTFDTAE EAAIVYDNAA IKIKGPNALT NFIKPPYDSG RESHSLSSPT 180 SVLRFQYTEE AGNEPQVLDG NVSRKAEEIK EKECDWRLDK QIDENDWKPV QCVAEEDPGG 240 YYFEELIDFE NHPPVCFDEC TIPDTELTDD FADVAVHLNL DGDFGSCLWN VDEYF*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	3e-22	105	162	1	59	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A	5e-22	103	162	2	62	ATERF1
3gcc_A	5e-22	103	162	2	62	ATERF1
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Functional Description ? help Back to Top
Source	Description
UniProt	Component of the cytokinin signaling pathway involved in cotyledons, leaves, and embryos development. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:16832061}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Manes.01G249600.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021612224.1	0.0	ethylene-responsive transcription factor CRF6-like
Swissprot	Q9SUE3	4e-46	CRF4_ARATH; Ethylene-responsive transcription factor CRF4
TrEMBL	A0A2C9WQC9	0.0	A0A2C9WQC9_MANES; Uncharacterized protein
STRING	cassava4.1_024908m	0.0	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF450	34	161

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G27950.1	2e-48	cytokinin response factor 4

Link Out ? help Back to Top
Phytozome	Manes.01G249600.1.p

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zwack PJ,Compton MA,Adams CI,Rashotte AM Cytokinin response factor 4 (CRF4) is induced by cold and involved in freezing tolerance. Plant Cell Rep., 2016. 35(3): p. 573-84 [PMID:26650835] Raines T, et al. The cytokinin response factors modulate root and shoot growth and promote leaf senescence in Arabidopsis. Plant J., 2016. 85(1): p. 134-47 [PMID:26662515]