PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.01G245600.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family bHLH
Protein Properties Length: 621aa    MW: 68410.8 Da    PI: 6.8005
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.01G245600.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH41.42.7e-13451497455
                          HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                  HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                          +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  Manes.01G245600.1.p 451 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAISYISELQ 497
                          799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.8E-5452240IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.231447496IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000834.30E-15450501No hitNo description
SuperFamilySSF474595.76E-18450510IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000109.0E-11451497IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.109.9E-18451510IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.1E-16453502IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 621 aa     Download sequence    Send to blast
MKIEIGMGGG AWSDEDRGMV AAVLGTKAFN YLISNLASNE NLLMAVGSDE NLQNKLSDLV  60
DHPNFSNFSW NYAIFWQISC SKSGDWVLGW GDGSCREPKE GEESEATRIL NLRFEDETQQ  120
RMRKRVLQKL HALSGESDED NYALGLDRVT DTEMFFLASM YFSFPRGEGG PGKCFASGKH  180
IWVADALRTG TDYCVRSFLA KSAGIQTIVL VATDVGVVEL GSVRSVPEST VIVQSIRSAF  240
SAHNTVIRAK PMVPAAAPAL PVVNEKKDEN SLFSNVGIVE RVEGIPKIFG QELNNSSHGH  300
GHGFREKLAV RKMEERASSW DVYQNGNRLA FPGNRNGLHG SSWAHNFGLK QGSTAEVYSS  360
QIAANNLQEL VNGVREEFRL NQFQPQKQVN MQIDFSGATS GPSMVGRPVN AESEHSDVEA  420
SCKEERRGTA DDRRPRKRGR KPANGREEPL NHVEAERQRR EKLNQRFYAL RAVVPNISKM  480
DKASLLGDAI SYISELQAKL KLMEADKEKF GNTSREASAL EVNSNGKTHS QAPEVDIQAS  540
HDEIIVRVSC PLDSHPASRV IQVFKEAKVS VIDSKFAAAN ETVFHTFVIK SQGSEQLTKE  600
KLMAAFSLEP NSLQQLSSVG *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A1e-28445517274Transcription factor MYC2
5gnj_B1e-28445517274Transcription factor MYC2
5gnj_E1e-28445517274Transcription factor MYC2
5gnj_F1e-28445517274Transcription factor MYC2
5gnj_G1e-28445517274Transcription factor MYC2
5gnj_I1e-28445517274Transcription factor MYC2
5gnj_M1e-28445517274Transcription factor MYC2
5gnj_N1e-28445517274Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1425441RRGTADDRRPRKRGRKP
2432440RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.01G245600.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021611767.10.0transcription factor bHLH13-like
RefseqXP_021611774.10.0transcription factor bHLH13-like
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A2C9WQ920.0A0A2C9WQ92_MANES; Uncharacterized protein
STRINGcassava4.1_005159m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF54483254
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]