PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.01G100400.1.p
Organism
Manihot esculenta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family WRKY
Protein Properties Length: 535aa    MW: 57906.7 Da    PI: 8.2898
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.01G100400.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY97.86.8e-31241297259
                          --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                 WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                          dDgynWrKYGqK++kg e+prsYY+Ct+ +C vkkkv rs+ d++++ei+Y+g Hnhe
  Manes.01G100400.1.p 241 DDGYNWRKYGQKPIKGCECPRSYYKCTHLNCLVKKKVGRSS-DGQITEIIYKGLHNHE 297
                          8****************************************.***************8 PP
2WRKY106.71.2e-33420478159
                          ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                 WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                          ldDgy+WrKYGqK+vkg+++prsYY+CtsagC+v+k+ver+a dpk+v++tYeg+Hnh+
  Manes.01G100400.1.p 420 LDDGYRWRKYGQKVVKGNPHPRSYYKCTSAGCNVRKHVERAAADPKAVVTTYEGKHNHD 478
                          59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.804.0E-27238300IPR003657WRKY domain
SuperFamilySSF1182902.09E-24239299IPR003657WRKY domain
SMARTSM007742.6E-34240298IPR003657WRKY domain
PROSITE profilePS5081122.366241299IPR003657WRKY domain
PfamPF031061.4E-23241297IPR003657WRKY domain
Gene3DG3DSA:2.20.25.808.9E-37405480IPR003657WRKY domain
SuperFamilySSF1182901.96E-29412480IPR003657WRKY domain
PROSITE profilePS5081138.457415480IPR003657WRKY domain
SMARTSM007746.5E-40420479IPR003657WRKY domain
PfamPF031064.2E-26421478IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 535 aa     Download sequence    Send to blast
MAGKQVSSAT KPAPPPPARP TISLPPRPSM DTLFTGGLSP GPMTLVSSFF SDNYPDSDCR  60
SFSQLLAGAM ASPIARPAFF TDISVPNNNN TSSVKQDGAE NSSNLGFKQS RPVNLVVAPS  120
PFFTVPPGLS PSGLLNSPGF FSPPQSPFGM SHQQALAQVT AQAAVAAQSH MHLQAQYQPA  180
PVAASTEILM PHPSFTTGEA SQQQQMLPST SEPPSSMAES SGLSHSDRNQ QPPIPVDKPS  240
DDGYNWRKYG QKPIKGCECP RSYYKCTHLN CLVKKKVGRS SDGQITEIIY KGLHNHEQPQ  300
PNKRAKDNSD INGGIHPQAK PELSSQDLAG NSNKLKETIP IHSVPGREQE STQVDPIELS  360
GSSDSEEAAD GARRAEEGDD DEPNPKRRHT DVEKSEAALP HKTVTEPKII VQTRSEVDLL  420
DDGYRWRKYG QKVVKGNPHP RSYYKCTSAG CNVRKHVERA AADPKAVVTT YEGKHNHDIP  480
AARNSSHNTA NKNAPQLKPQ KVVADKHPLL KGMDFGNSDQ RPVLLRLKEE EIAV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A2e-40241481878Probable WRKY transcription factor 4
2lex_A2e-40241481878Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.01G100400.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKT8276480.0KT827648.1 Manihot esculenta WRKY transcription factor 73 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021633755.10.0probable WRKY transcription factor 4 isoform X1
SwissprotQ9XI901e-145WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLA0A140H8S70.0A0A140H8S7_MANES; WRKY transcription factor 73
STRINGcassava4.1_005267m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF154534100
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G03340.11e-114WRKY DNA-binding protein 3
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Wei Y, et al.
    Genome-Wide Identification and Expression Analysis of the WRKY Gene Family in Cassava.
    Front Plant Sci, 2016. 7: p. 25
    [PMID:26904033]
  4. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]