PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum

Family

HSF

Protein Properties

Length: 432aa MW: 48545.4 Da PI: 5.3402

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MLOC_74270.1	genome	IBSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	106.6	2e-33	13	103	2	101
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Fl k+ye++++++++ ++ w+ +g+sfvv+ + +f +++LpkyFkh+nf+SFvRQLn+YgF+kv+ e+ weF++++F +++++ l++i+ MLOC_74270.1 13 FLIKTYEMVDEPATDAVVAWTPSGTSFVVFSQADFCRDLLPKYFKHNNFSSFVRQLNTYGFRKVDPEQ---------WEFANEEFIRDQRHRLKNIH 100 9*************************************************************9998.........****************** PP XXX CS HSF_DNA-bind 99 rkk 101 r+k MLOC_74270.1 101 RRK 103 *98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46785	6.12E-33	8	102	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	5.7E-59	9	102	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Gene3D	G3DSA:1.10.10.10	2.3E-36	10	102	IPR011991	Winged helix-turn-helix DNA-binding domain
PRINTS	PR00056	3.7E-20	13	36	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	1.9E-29	13	102	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	3.7E-20	51	63	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	52	76	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	3.7E-20	64	76	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009408	Biological Process	response to heat
GO:0009733	Biological Process	response to auxin
GO:0009958	Biological Process	positive gravitropism
GO:0048527	Biological Process	lateral root development
GO:0048530	Biological Process	fruit morphogenesis
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 432 aa Download sequence Send to blast
MEGSGGSSSL PPFLIKTYEM VDEPATDAVV AWTPSGTSFV VFSQADFCRD LLPKYFKHNN 60 FSSFVRQLNT YGFRKVDPEQ WEFANEEFIR DQRHRLKNIH RRKPIFSHSS HTQGAGPLAD 120 SERRDYEEEI ERLKCENASL NLQLERKKTD MDSKMKALED KLLAIEDQQR NLISYVTEIV 180 KAPGFLSSFI EQSDHHGKKR RLPKSISFHE GASTQGNQIM HCDLANSPAH KLYRESFDKM 240 ESSLNSLENF FKEATEALGN DISYDGDVPR HSSAVVLTEL HSSGESDPHA QSPPSMMHTC 300 SAGVGDSHSS RDIAESASCP ESPPLPEAHS RADSRAKVSD IDVNLEPAVT ETGPSRDQQP 360 TQDPPADAND GFWQQFLTEQ PGSSDTHQEA QSERRDREAN QTVTRDRGSF WWGKSVEQMT 420 EKLGHLTSAE KT

Sequence ? help Back to Top

Protein Sequence Length: 432 aa Download sequence Send to blast

MEGSGGSSSL PPFLIKTYEM VDEPATDAVV AWTPSGTSFV VFSQADFCRD LLPKYFKHNN  60
FSSFVRQLNT YGFRKVDPEQ WEFANEEFIR DQRHRLKNIH RRKPIFSHSS HTQGAGPLAD  120
SERRDYEEEI ERLKCENASL NLQLERKKTD MDSKMKALED KLLAIEDQQR NLISYVTEIV  180
KAPGFLSSFI EQSDHHGKKR RLPKSISFHE GASTQGNQIM HCDLANSPAH KLYRESFDKM  240
ESSLNSLENF FKEATEALGN DISYDGDVPR HSSAVVLTEL HSSGESDPHA QSPPSMMHTC  300
SAGVGDSHSS RDIAESASCP ESPPLPEAHS RADSRAKVSD IDVNLEPAVT ETGPSRDQQP  360
TQDPPADAND GFWQQFLTEQ PGSSDTHQEA QSERRDREAN QTVTRDRGSF WWGKSVEQMT  420
EKLGHLTSAE KT

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	9e-29	3	102	19	129	Heat shock factor protein 1
5d5v_B	9e-29	3	102	19	129	Heat shock factor protein 1
5d5v_D	9e-29	3	102	19	129	Heat shock factor protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE). {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	MLOC_74270.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK371121	0.0	AK371121.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv2125M08.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020165982.1	0.0	heat stress transcription factor A-4b
Swissprot	Q94J16	0.0	HFA4B_ORYSJ; Heat stress transcription factor A-4b
TrEMBL	F2E4P7	0.0	F2E4P7_HORVV; Predicted protein
STRING	MLOC_74270.1	0.0	(Hordeum vulgare)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP3296	37	78

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G45710.1	4e-76	HSF family protein

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Shim D, et al. Orthologs of the class A4 heat shock transcription factor HsfA4a confer cadmium tolerance in wheat and rice. Plant Cell, 2009. 21(12): p. 4031-43 [PMID:20028842] Guan JC, et al. A 9 bp cis-element in the promoters of class I small heat shock protein genes on chromosome 3 in rice mediates L-azetidine-2-carboxylic acid and heat shock responses. J. Exp. Bot., 2010. 61(15): p. 4249-61 [PMID:20643810]