PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum

Family

MYB_related

Protein Properties

Length: 236aa MW: 25712.5 Da PI: 5.8075

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MLOC_73037.2	genome	IBSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	24.8	5.2e-08	33	59	21	48
TT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 21 ggtWktIartmgkgRtlkqcksrwqkyl 48 +++W++Ia++++ gRt++++k+ w+++l MLOC_73037.2 33 TDRWSAIAARLP-GRTDNEIKNVWHTHL 59 457*******.**********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	5.06E-8	31	64	IPR009057	Homeodomain-like
Pfam	PF00249	1.0E-6	32	59	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	5.1E-12	32	63	IPR009057	Homeodomain-like
CDD	cd00167	7.82E-5	33	59	No hit	No description
PROSITE profile	PS50090	6.388	35	59	IPR017877	Myb-like domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 236 aa Download sequence Send to blast
PHPLPLVVFL LHHIFTVPQK WWQSLLLCFN CKTDRWSAIA ARLPGRTDNE IKNVWHTHLK 60 KRLDPSAQEQ HEEAGVAKKR KKPAAAAAPR KRDGKVKMRN LNALTARAAA AAPVSSPERS 120 VSSTVTESTS TASAAAEQHG NSGSSSASAS ASVKEECFTS SEESEEFQID ESFWSETLSM 180 PLDDLNDVCM EPHDAFGKPD GDMDYWLRLF MEGGGGSGSG SDDNNNHDGA LDLPQI

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	59	81	KKRLDPSAQEQHEEAGVAKKRKK
2	77	81	KKRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cold stress response (PubMed:14675437, PubMed:20807373, PubMed:22246661). Regulates positively the expression of genes involved in reactive oxygen species (ROS) scavenging such as peroxidase and superoxide dismutase during cold stress. Transactivates a complex gene network that have major effects on stress tolerance and panicle development (PubMed:20807373). {ECO:0000269\|PubMed:14675437, ECO:0000269\|PubMed:20807373, ECO:0000269\|PubMed:22246661}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	MLOC_73037.2

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cold stress. {ECO:0000269\|PubMed:14675437, ECO:0000269\|PubMed:20807373, ECO:0000269\|Ref.2}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK353929	0.0	AK353929.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv1003N07.
GenBank	AK359880	0.0	AK359880.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv1105F18.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020164748.1	2e-74	myb-related protein Myb4-like
Swissprot	Q7XBH4	1e-43	MYB4_ORYSJ; Transcription factor MYB4
TrEMBL	Q96463	1e-86	Q96463_HORVU; Myb4 transcription factor (Fragment)
STRING	MLOC_73037.2	1e-175	(Hordeum vulgare)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP79	38	563

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23250.2	2e-14	myb domain protein 15

Publications ? help Back to Top
Park MR, et al. Supra-optimal expression of the cold-regulated OsMyb4 transcription factor in transgenic rice changes the complexity of transcriptional network with major effects on stress tolerance and panicle development. Plant Cell Environ., 2010. 33(12): p. 2209-30 [PMID:20807373] Soltész A, et al. The rice Osmyb4 gene enhances tolerance to frost and improves germination under unfavourable conditions in transgenic barley plants. J. Appl. Genet., 2012. 53(2): p. 133-43 [PMID:22246661]