PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum

Family

bHLH

Protein Properties

Length: 393aa MW: 41912.3 Da PI: 7.4355

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MLOC_57622.3	genome	IBSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.3	1.3e-08	195	242	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR+ri +++ L++l+P + +k Ka +L + ++Y++sLq MLOC_57622.3 195 SHSLAERVRRERISQRMKFLQDLVPGC----NKVIGKALMLDEIINYVQSLQ 242 8***********************9....677***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	3.66E-16	189	256	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	9.96E-10	189	246	No hit	No description
PROSITE profile	PS50888	14.964	191	241	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.8E-15	191	254	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	8.2E-6	195	242	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.3E-8	197	247	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009637	Biological Process	response to blue light
GO:0005634	Cellular Component	nucleus
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 393 aa Download sequence Send to blast
MEGRAGGGSG DYISSLLTSS PMLDFGMLDG AVTAGGDCLD KFCGDPGFAE RAARLSSFNG 60 QHLAPGLLGM LPPAPGGEFG GSREASSVSD PASAMKDANA KKRKAPASKG KAKEPSLSTS 120 CQVGEHKEPD AKRCRTGDAE KKAAAPVRPK AEQAGSDSSV EDGEQRKGKG KNAKPVEPPK 180 DYVHVRARRG QATDSHSLAE RVRRERISQR MKFLQDLVPG CNKVIGKALM LDEIINYVQS 240 LQRQVEFLSM KLATVNPLDF SNLPTLLHKD MYGPSASSVF SLESSSSAFP FSDQGDVFQS 300 FLPNSMESQC TLNQLDLALS QATNAAQYGF QDATASTNLQ QVILALRILW VLASLDAGLI 360 LIHFGFVARL SAEELLGGRS PERFSCGQQT EPG

Sequence ? help Back to Top

Protein Sequence Length: 393 aa Download sequence Send to blast

MEGRAGGGSG DYISSLLTSS PMLDFGMLDG AVTAGGDCLD KFCGDPGFAE RAARLSSFNG  60
QHLAPGLLGM LPPAPGGEFG GSREASSVSD PASAMKDANA KKRKAPASKG KAKEPSLSTS  120
CQVGEHKEPD AKRCRTGDAE KKAAAPVRPK AEQAGSDSSV EDGEQRKGKG KNAKPVEPPK  180
DYVHVRARRG QATDSHSLAE RVRRERISQR MKFLQDLVPG CNKVIGKALM LDEIINYVQS  240
LQRQVEFLSM KLATVNPLDF SNLPTLLHKD MYGPSASSVF SLESSSSAFP FSDQGDVFQS  300
FLPNSMESQC TLNQLDLALS QATNAAQYGF QDATASTNLQ QVILALRILW VLASLDAGLI  360
LIHFGFVARL SAEELLGGRS PERFSCGQQT EPG

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds DNA to G box 5'-CACGTG-3' and to E-box 5'-CANNTG-3' (By similarity). Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light (PubMed:24130508). {ECO:0000250\|UniProtKB:Q8GY61, ECO:0000269\|PubMed:24130508}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00036	PBM	Transfer from AT5G48560	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	MLOC_57622.3

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK367580	0.0	AK367580.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv2059B18.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020146738.1	0.0	transcription factor bHLH78-like isoform X2
Swissprot	Q9FJL4	5e-58	BH078_ARATH; Transcription factor bHLH78
TrEMBL	A0A287WII9	0.0	A0A287WII9_HORVV; Uncharacterized protein
STRING	MLOC_57622.3	0.0	(Hordeum vulgare)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP919	38	137

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G07340.1	3e-56	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281]