PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum

Family

C2H2

Protein Properties

Length: 82aa MW: 9571.96 Da PI: 8.3553

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MLOC_41788.1	genome	IBSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.1	0.0003	24	49	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 y+C+ C++sF k +L H r + MLOC_41788.1 24 YTCSieGCSMSFDMKNELSLHERHiC 49 99*******************99755 PP
2	zf-C2H2	17	1.7e-05	47	71	1	23
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 + Cp Cgk F ++ +L +H +H MLOC_41788.1 47 HICPvdGCGKKFFTHKHLLQHREVH 71 68*******************9988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.7E-4	23	46	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	22	24	46	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	3.79E-6	46	73	No hit	No description
SMART	SM00355	0.0059	47	71	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.741	47	76	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	1.9E-8	47	72	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	49	71	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 82 aa Download sequence Send to blast
MKQLKEARGE ERTPRDDPMR VEGYTCSIEG CSMSFDMKNE LSLHERHICP VDGCGKKFFT 60 HKHLLQHREV HTETTKQLKK AT

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6a57_A	2e-17	23	73	22	72	Lysine-specific demethylase REF6
6a58_A	2e-17	23	73	22	72	Lysine-specific demethylase REF6
6a59_A	2e-17	23	73	22	72	Lysine-specific demethylase REF6
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3 with a specific activity for H3K27me3 and H3K27me2. No activity on H3K4me3, H3K9me3, H3K27me1 and H3K36me3. Involved in biotic stress response. May demethylate H3K27me3-marked defense-related genes and increase their basal and induced expression levels during pathogen infection. {ECO:0000269\|PubMed:24280387}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	MLOC_41788.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salt stress, abscisic acid (ABA), jasmonic acid (JA), the ethylene precursor ACC and infection by the bacterial pathogen Xanthomonas oryzae pv. oryzae. {ECO:0000269\|PubMed:24280387}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020164795.1	1e-40	lysine-specific demethylase JMJ705-like
Swissprot	Q5N712	2e-22	JM705_ORYSJ; Lysine-specific demethylase JMJ705
TrEMBL	A0A287J466	4e-50	A0A287J466_HORVV; Uncharacterized protein
TrEMBL	A0A287NI62	3e-50	A0A287NI62_HORVV; Uncharacterized protein
STRING	MLOC_41788.1	4e-55	(Hordeum vulgare)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP5346	32	46

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G48430.1	3e-19	relative of early flowering 6

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764]