PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MLOC_11665.11
Organism
Hordeum vulgare
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum
Family C2H2
Protein Properties Length: 82aa    MW: 9500.81 Da    PI: 8.658
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MLOC_11665.11genomeIBSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H224.95.1e-08832123
                   EEET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                   ++Cp   Cgk Fs   nLk H++tH
  MLOC_11665.11  8 FVCPheGCGKAFSLDFNLKAHMKTH 32
                   89**********************9 PP
2zf-C2H218.94e-063863123
                   EEET..TTTEEESSHHHHHHHHHH.T CS
        zf-C2H2  1 ykCp..dCgksFsrksnLkrHirt.H 23
                   + Cp   Cg++F++ s L+ H r  H
  MLOC_11665.11 38 HMCPypECGRRFTQESKLRAHFRAqH 63
                   689999***************99877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.607.5E-15332IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PfamPF138940.0011832No hitNo description
SMARTSM003554.3E-4832IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.739837IPR007087Zinc finger, C2H2
PROSITE patternPS0002801032IPR007087Zinc finger, C2H2
SuperFamilySSF576677.71E-111864No hitNo description
PfamPF138947.6E-43863No hitNo description
Gene3DG3DSA:3.30.160.606.4E-93860IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.00773863IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.0323863IPR007087Zinc finger, C2H2
PROSITE patternPS0002804063IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 82 aa     Download sequence    Send to blast
MWEGEKNFVC PHEGCGKAFS LDFNLKAHMK THFADNYHMC PYPECGRRFT QESKLRAHFR  60
AQHEKNLGGP VMNPGVYSRV QT
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C2e-1445959114PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMLOC_11665.11
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3569601e-117AK356960.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, complete cds, clone: NIASHv1042P17.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020149434.14e-44uncharacterized zinc finger protein At4g06634 isoform X2
SwissprotQ2V3L39e-24YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A3B6PN626e-48A0A3B6PN62_WHEAT; Uncharacterized protein
TrEMBLA0A446WCB16e-48A0A446WCB1_TRITD; Uncharacterized protein
TrEMBLA0A453NX192e-48A0A453NX19_AEGTS; Uncharacterized protein
STRINGMLOC_11665.63e-51(Hordeum vulgare)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.23e-26C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]