PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

DBB

Protein Properties

Length: 179aa MW: 19442.1 Da PI: 7.3388

Description

DBB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C023341P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-B_box	28.8	2.5e-09	3	43	4	38
zf-B_box 4 rkCpeHeekelqlfCedCqqllCedClleeHkg......Ht 38 +C+ ++++e++ fC +++ lC+ C + H+ H+ MELO3C023341P1 3 IRCDVCDKEEASVFCPSDEAALCPACDRQVHRAnklaskHS 43 58*****************************7666666665 PP
2	zf-B_box	23.8	9.5e-08	59	96	3	38
zf-B_box 3 erkCpeHeekelqlfCedCqqllCedClleeHkg..Ht 38 ++ C+ ++ +++ lfC++++ lC++C +H Ht MELO3C023341P1 59 QPLCDVCQIQRAFLFCREDRAILCRECDIPIHDTseHT 96 789****************************9546765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50119	10.751	1	47	IPR000315	B-box-type zinc finger
Pfam	PF00643	1.1E-7	3	44	IPR000315	B-box-type zinc finger
CDD	cd00021	2.17E-6	3	47	No hit	No description
SMART	SM00336	2.3E-9	4	47	IPR000315	B-box-type zinc finger
PROSITE profile	PS50119	10.253	57	104	IPR000315	B-box-type zinc finger
SMART	SM00336	2.7E-11	57	104	IPR000315	B-box-type zinc finger
Pfam	PF00643	2.1E-6	59	99	IPR000315	B-box-type zinc finger
CDD	cd00021	1.39E-6	60	104	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005622	Cellular Component	intracellular
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 179 aa Download sequence Send to blast
MKIRCDVCDK EEASVFCPSD EAALCPACDR QVHRANKLAS KHSRFSLLHS AASAAATSQP 60 LCDVCQIQRA FLFCREDRAI LCRECDIPIH DTSEHTQKHS RFLLTGVKVS PSTATSSSCS 120 SSVGSGGEEN EGLLKKCSRK RSKMGFSKGL VISEYLESLP GWCVEDFLDS SSSPHILL*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that acts as positive regulator of seedling photomorphogenesis (PubMed:17965270). Acts downstream of COP1 and play an important role in early and long-term adjustment of the shade avoidance syndrome (SAS) responses in natural environments (PubMed:21070414). {ECO:0000269\|PubMed:17965270, ECO:0000269\|PubMed:21070414}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681912	0.0	LN681912.1 Cucumis melo genomic scaffold, anchoredscaffold00059.
GenBank	LN713265	0.0	LN713265.1 Cucumis melo genomic chromosome, chr_11.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008461001.1	1e-127	PREDICTED: B-box zinc finger protein 21-like
Swissprot	Q9LQZ7	5e-55	BBX21_ARATH; B-box zinc finger protein 21
TrEMBL	A0A1S3CDR2	1e-126	A0A1S3CDR2_CUCME; B-box zinc finger protein 21-like
STRING	XP_008461001.1	1e-126	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1448	34	94

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G75540.1	1e-52	salt tolerance homolog2

Publications ? help Back to Top
Xu D, et al. BBX21, an Arabidopsis B-box protein, directly activates HY5 and is targeted by COP1 for 26S proteasome-mediated degradation. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(27): p. 7655-60 [PMID:27325768] Xu DB, et al. The G-Protein β Subunit AGB1 Promotes Hypocotyl Elongation through Inhibiting Transcription Activation Function of BBX21 in Arabidopsis. Mol Plant, 2017. 10(9): p. 1206-1223 [PMID:28827171] Xu D,Jiang Y,Li J,Holm M,Deng XW The B-Box Domain Protein BBX21 Promotes Photomorphogenesis. Plant Physiol., 2018. 176(3): p. 2365-2375 [PMID:29259103] Job N,Yadukrishnan P,Bursch K,Datta S,Johansson H Two B-Box Proteins Regulate Photomorphogenesis by Oppositely Modulating HY5 through their Diverse C-Terminal Domains. Plant Physiol., 2018. 176(4): p. 2963-2976 [PMID:29439209] Crocco CD,Ocampo GG,Ploschuk EL,Mantese A,Botto JF Heterologous Expression of AtBBX21 Enhances the Rate of Photosynthesis and Alleviates Photoinhibition in Solanumtuberosum. Plant Physiol., 2018. 177(1): p. 369-380 [PMID:29555784] Kang X, et al. HRB2 and BBX21 interaction modulates Arabidopsis ABI5 locus and stomatal aperture. Plant Cell Environ., 2018. 41(8): p. 1912-1925 [PMID:29748960]