PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

HD-ZIP

Protein Properties

Length: 279aa MW: 31988.2 Da PI: 4.3669

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C021534P2	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	62.4	6.5e-20	65	118	3	56
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 k++++t+eq++ Le Fe+++++ e+++eLAkklgL+ rqV vWFqNrRa++k MELO3C021534P2 65 KKRRLTQEQVHLLEISFESENKLEPERKTELAKKLGLQPRQVAVWFQNRRARWK 118 5678*************************************************9 PP
2	HD-ZIP_I/II	128.6	2.6e-41	64	156	1	93
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 ekkrrl++eqv+lLE sFe+e+kLeperK+ela++LglqprqvavWFqnrRAR+ktkqlE+dy+ Lk++yd+ +++ + + ke+e+L++e+++ MELO3C021534P2 64 EKKRRLTQEQVHLLEISFESENKLEPERKTELAKKLGLQPRQVAVWFQNRRARWKTKQLERDYDLLKSSYDSFRSSYDFIAKENERLKAEVAS 156 69***********************************************************************************99999865 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	7.7E-20	48	122	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.799	60	120	IPR001356	Homeobox domain
SMART	SM00389	2.5E-19	63	124	IPR001356	Homeobox domain
CDD	cd00086	3.80E-18	65	121	No hit	No description
Pfam	PF00046	4.2E-17	65	118	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	2.4E-21	66	127	IPR009057	Homeodomain-like
PRINTS	PR00031	1.4E-6	91	100	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	95	118	IPR017970	Homeobox, conserved site
PRINTS	PR00031	1.4E-6	100	116	IPR000047	Helix-turn-helix motif
Pfam	PF02183	1.0E-16	120	162	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0001558	Biological Process	regulation of cell growth
GO:0009637	Biological Process	response to blue light
GO:0009651	Biological Process	response to salt stress
GO:0009965	Biological Process	leaf morphogenesis
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0042803	Molecular Function	protein homodimerization activity
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 279 aa Download sequence Send to blast
MMSDGLIFNR SPGHANMLFF GSSDPIPRGP SFMMGMEETS KRRSFFSSPD DLFDDDYYDD 60 QPPEKKRRLT QEQVHLLEIS FESENKLEPE RKTELAKKLG LQPRQVAVWF QNRRARWKTK 120 QLERDYDLLK SSYDSFRSSY DFIAKENERL KAEVASLTEK LQAKEVVESS FHAKNPDPFL 180 EDQLLVPVVQ QNIKIEDHHS CRSNGSAVLD EDGPQLLDSG DSYILSNDYD GCVLPAFGVN 240 SEEEDGSDDG QGYFSDVYTT VDQQTHEGEP LTWWDWTS*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	112	120	RRARWKTKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription activator involved in leaf development. Binds to the DNA sequence 5'-CAAT[AT]ATTG-3'. {ECO:0000269\|PubMed:8535134}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00323	DAP	Transfer from AT3G01470	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681890	0.0	LN681890.1 Cucumis melo genomic scaffold, anchoredscaffold00048.
GenBank	LN713263	0.0	LN713263.1 Cucumis melo genomic chromosome, chr_9.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008458752.1	0.0	PREDICTED: homeobox-leucine zipper protein HAT5-like
Swissprot	Q02283	9e-86	HAT5_ARATH; Homeobox-leucine zipper protein HAT5
TrEMBL	A0A1S3C9T9	0.0	A0A1S3C9T9_CUCME; homeobox-leucine zipper protein HAT5-like
STRING	XP_008458752.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF11283	30	39

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G01470.1	2e-75	homeobox 1

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Ribone PA,Capella M,Arce AL,Chan RL A uORF Represses the Transcription Factor AtHB1 in Aerial Tissues to Avoid a Deleterious Phenotype. Plant Physiol., 2017. 175(3): p. 1238-1253 [PMID:28956754]