PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

G2-like

Protein Properties

Length: 338aa MW: 36910.1 Da PI: 5.8557

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C020611P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	95.1	5.4e-30	158	211	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 +prl+Wtp+LH+rFv++v++L G+++A+Pkti++lm+v+gLt+e+v+SHLQkYRl MELO3C020611P1 158 RPRLVWTPQLHKRFVDVVAHL-GIKNAVPKTIMQLMNVEGLTRENVASHLQKYRL 211 59*****************.******************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	10.061	155	214	IPR017930	Myb domain
SuperFamily	SSF46689	1.67E-19	155	215	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	3.7E-30	157	216	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	1.7E-23	159	211	IPR006447	Myb domain, plants
Pfam	PF00249	6.0E-8	161	210	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0042753	Biological Process	positive regulation of circadian rhythm
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 338 aa Download sequence Send to blast
MGEEVKMAEY ESGGGGGGGE DESCAHEERV FEWETGLPDA DDLTPLSQTL IPPELASAFS 60 ISTGPCRTLM DVNRASQNTL SNLRGFQAQA FSSNNFKSFN DDRTQDHDPM VVEGDEATER 120 DAGSDSRKLR KVDCAEEADS ALRTDNSMDD PSARTLKRPR LVWTPQLHKR FVDVVAHLGI 180 KNAVPKTIMQ LMNVEGLTRE NVASHLQKYR LYLKRMQGSS NEGPSSPDRI FASTPVPQTL 240 HESTNSGQAN GNGHLPVPTP MPYGPPMMPM PVLGMAASGH AHSYMGMPVA HPGSAQGYPG 300 FETHPFNMMH QRDWSGNKYS SIVPYPHPHV PPNTNDK*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5lxu_A	5e-35	158	214	1	57	Transcription factor LUX
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:21236673, ECO:0000269\|PubMed:21753751, ECO:0000269\|PubMed:22311777}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00014	PBM	Transfer from AT3G46640	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian oscillation with peaks at subjective dusk. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:17132630, ECO:0000269\|PubMed:21753751}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681926	0.0	LN681926.1 Cucumis melo genomic scaffold, anchoredscaffold00044.
GenBank	LN713266	0.0	LN713266.1 Cucumis melo genomic chromosome, chr_12.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008457454.1	0.0	PREDICTED: transcription factor PCL1-like
Refseq	XP_008457455.1	0.0	PREDICTED: transcription factor PCL1-like
Swissprot	Q9SNB4	2e-84	PCL1_ARATH; Transcription factor LUX
TrEMBL	A0A1S3C5J0	0.0	A0A1S3C5J0_CUCME; transcription factor PCL1-like
STRING	XP_008457454.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF6957	33	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G46640.2	2e-80	G2-like family protein

Publications ? help Back to Top
Higham CF,Husmeier D A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics, 2013. 14 Suppl 10: p. S3 [PMID:24267177]