PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

WRKY

Protein Properties

Length: 306aa MW: 34377.6 Da PI: 6.1848

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C019679P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	104.9	4.2e-33	182	239	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 +Dgy+WrKYGqK vk+s+fprsYY+Cts++C+vkk+vers+edp +v++tYeg+Hnh MELO3C019679P1 182 EDGYRWRKYGQKAVKNSPFPRSYYKCTSQNCSVKKRVERSSEDPGFVITTYEGKHNHY 239 8********************************************************5 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	6.2E-34	168	239	IPR003657	WRKY domain
SuperFamily	SSF118290	8.11E-29	174	241	IPR003657	WRKY domain
PROSITE profile	PS50811	32.179	176	241	IPR003657	WRKY domain
SMART	SM00774	1.8E-38	181	240	IPR003657	WRKY domain
Pfam	PF03106	2.9E-26	182	238	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 306 aa Download sequence Send to blast
MSNEGHDHEK EEDDPYYPQF DPFTHNFHHQ KPFEVPPPLT NPYSEAFDIA PYNVGFYSDF 60 SHASSQYDYH NIFSTPFEMS CSSSEVISSV DDALKKSSSL GRDLSSVVTG EHPLTPNCSS 120 TTCSSDEVVA GGGDSSKSGE VKGFDDKKGE NSKKVDEGKK KEKREKGPRF AFLTKTEIDN 180 LEDGYRWRKY GQKAVKNSPF PRSYYKCTSQ NCSVKKRVER SSEDPGFVIT TYEGKHNHYC 240 PITLRGHNPT GVLPPSVTPP LFPPSPNFFS AESFCENLHQ QYQYGLFQDF INNPSFNNSN 300 QHPSN*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	1e-27	174	241	10	77	Probable WRKY transcription factor 4
2lex_A	1e-27	174	241	10	77	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681921	0.0	LN681921.1 Cucumis melo genomic scaffold, anchoredscaffold00039.
GenBank	LN713265	0.0	LN713265.1 Cucumis melo genomic chromosome, chr_11.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008456349.1	0.0	PREDICTED: probable WRKY transcription factor 12
Swissprot	Q8VWJ2	5e-43	WRK28_ARATH; WRKY transcription factor 28
TrEMBL	A0A1S3C4A4	0.0	A0A1S3C4A4_CUCME; probable WRKY transcription factor 12
STRING	XP_008456349.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF24673	3	3

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G29860.1	6e-41	WRKY DNA-binding protein 71

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kim SH, et al. Characterization of a Novel DWD protein that participates in heat stress response in Arabidopsis. Mol. Cells, 2014. 37(11): p. 833-40 [PMID:25358503] Zhao L, et al. KLU suppresses megasporocyte cell fate through SWR1-mediated activation of WRKY28 expression in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2018. 115(3): p. E526-E535 [PMID:29288215]