PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

C2H2

Protein Properties

Length: 270aa MW: 29416 Da PI: 5.001

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C019567P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.8	0.00036	112	134	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C + F ++ L H++ H MELO3C019567P1 112 FSCNYCQRKFFSSQALGGHQNAH 134 89*****************9988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	4.05E-6	110	139	No hit	No description
PROSITE profile	PS50157	11.344	112	139	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	114	134	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 270 aa Download sequence Send to blast
MKPFLDLEKE PSCLANDSDI SSQVASSNYI SPLHENSNDN SLITNSSFLA NPNIPAADQP 60 GFESVCLELT LNFNIEDLET RPDSTGFSLS STSDQSSNEP TACATMAVPR VFSCNYCQRK 120 FFSSQALGGH QNAHKRERTL AKRAMRMGIL ADRYVSLASL PLKGSSFKSL GIKAHSSLLH 180 GVAAPMKPNE IRSSARFEPE PGYIGMPLFL EDDEAEVMWP GSFRPMVETR STHELTRPSF 240 ILTGISSISS ADKTSEDVEN STLDLTLKL*

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development. {ECO:0000269\|PubMed:24808098}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681851	0.0	LN681851.1 Cucumis melo genomic scaffold, anchoredscaffold00038.
GenBank	LN713260	0.0	LN713260.1 Cucumis melo genomic chromosome, chr_6.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008456195.1	0.0	PREDICTED: zinc finger protein 4-like
Swissprot	Q39263	3e-39	ZFP4_ARATH; Zinc finger protein 4
TrEMBL	A0A1S3C2N5	0.0	A0A1S3C2N5_CUCME; zinc finger protein 4-like
STRING	XP_008456195.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1323	31	92

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G66140.1	1e-41	zinc finger protein 4

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Joseph MP, et al. The Arabidopsis ZINC FINGER PROTEIN3 Interferes with Abscisic Acid and Light Signaling in Seed Germination and Plant Development. Plant Physiol., 2014. 165(3): p. 1203-1220 [PMID:24808098] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470]