PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C019226P1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family bHLH
Protein Properties Length: 239aa    MW: 26840.6 Da    PI: 7.2967
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C019226P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH37.35.1e-1279128355
                     HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
             HLH   3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                     +++  rE++RRd++N++f eL  +l +    + +K +K++iL  A++ + +Lq
  MELO3C019226P1  79 TSKACREKQRRDKLNERFLELAAVLEPG---KPPKTDKVAILSDAIRMMTDLQ 128
                     67889**********************9...99***************99998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088813.28176127IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.4E-1379149IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.9E-979128IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.61E-979132No hitNo description
SuperFamilySSF474591.14E-1381151IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003536.2E-1082133IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 239 aa     Download sequence    Send to blast
MDYPPPNWNW LFDCSTMDDL AVVDPRFSPP QSISFSWSNP SISFVSKDSL EVDCSYEDLD  60
STKEVGRKRL RGETSAASTS KACREKQRRD KLNERFLELA AVLEPGKPPK TDKVAILSDA  120
IRMMTDLQCE TQKLRESKED LKAKIKELKV EKNELRDEKQ RLRAEKEKLE LQIRAVNTRA  180
ADVQHPPPTL SAAFTAQGQA AGNKLMPFIG YPGIAMWQFL PPAAVDISQD HVLRPPVA*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
16571GRKRLRG
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269|PubMed:17028341}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6819161e-150LN681916.1 Cucumis melo genomic scaffold, anchoredscaffold00037.
GenBankLN7132651e-150LN713265.1 Cucumis melo genomic chromosome, chr_11.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008455829.11e-176PREDICTED: transcription factor ILR3-like
SwissprotQ9FH372e-82ILR3_ARATH; Transcription factor ILR3
TrEMBLA0A1S3C2I21e-175A0A1S3C2I2_CUCME; transcription factor ILR3-like
STRINGXP_008455829.11e-175(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF16023486
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G54680.12e-83bHLH family protein
Publications ? help Back to Top
  1. Li X,Zhang H,Ai Q,Liang G,Yu D
    Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana.
    Plant Physiol., 2016. 170(4): p. 2478-93
    [PMID:26921305]
  2. Aparicio F,Pallás V
    The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response.
    Mol. Plant Pathol., 2017. 18(2): p. 173-186
    [PMID:26929142]
  3. Liang G,Zhang H,Li X,Ai Q,Yu D
    bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana.
    J. Exp. Bot., 2017. 68(7): p. 1743-1755
    [PMID:28369511]
  4. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  5. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  6. Min JH, et al.
    Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element.
    Front Plant Sci, 2017. 8: p. 2100
    [PMID:29321786]
  7. Samira R, et al.
    The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis.
    Plant Mol. Biol., 2018. 97(4-5): p. 297-309
    [PMID:29882068]