PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C018864P1
Organism
Cucumis melo
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family C2H2
Protein Properties Length: 427aa    MW: 47447.3 Da    PI: 8.9279
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C018864P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H215.93.7e-056484323
                    ETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  3 CpdCgksFsrksnLkrHirtH 23
                    C++Cgk F r  nL+ H r H
  MELO3C018864P1 64 CEICGKGFQRDQNLQLHRRGH 84
                    *******************88 PP
2zf-C2H2130.00031140162123
                     EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                     +kC++C+k +  +s+ k H +t+
  MELO3C018864P1 140 WKCEKCSKKYAVQSDWKAHSKTC 162
                     58*****************9998 PP
3zf-C2H212.20.00054170188523
                     TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   5 dCgksFsrksnLkrHirtH 23 
                     dCg++Fsr++++++H   +
  MELO3C018864P1 170 DCGTPFSRRDSYVTHRAYC 188
                     8**************8765 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576673.18E-66184No hitNo description
Gene3DG3DSA:3.30.160.603.6E-56184IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0766284IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.4896284IPR007087Zinc finger, C2H2
PROSITE patternPS0002806484IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.8E-4128161IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.18E-6135160No hitNo description
SMARTSM00355140140160IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 427 aa     Download sequence    Send to blast
MSEEQTISNA FICSIPSLGS INSNNNNPSV IVKKKRNLPG NPDPEAEVVS LSPKTLMATN  60
RFLCEICGKG FQRDQNLQLH RRGHNLPWKL KQRSNGNKEP RKRVYVCPEK SCVHHHPSRA  120
LGDLTGIKKH FCRKHGEKKW KCEKCSKKYA VQSDWKAHSK TCGTKEYKCD CGTPFSRRDS  180
YVTHRAYCVA LAEETARLNA ASTNIAINNN SLADGYINNN PPQLFFPNSS NLFKPNETSP  240
IFFSNNNAPT ISLPFWLPTN PHQVNNFHYP TTTTTTTTTN SDVLSVPSLF SNEEQQSSHQ  300
FMSSSPNMSA TVLLQKAAQI GVTTDHPSSL MESFGLKFSS ITDGKALLSG IYGSMINSNS  360
NNVIIPLSEE DHHHHHHHHL YSAPPAKRMR HTVSEESVNG GEGETRDFLG VGMHTICHPS  420
TVNGWI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C8e-34136204371Zinc finger protein JACKDAW
5b3h_F8e-34136204371Zinc finger protein JACKDAW
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6817920.0LN681792.1 Cucumis melo genomic scaffold, anchoredscaffold00034.
GenBankLN7132550.0LN713255.1 Cucumis melo genomic chromosome, chr_1.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008455492.10.0PREDICTED: zinc finger protein NUTCRACKER
SwissprotQ9ZWA61e-130IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBLA0A1S3C1140.0A0A1S3C114_CUCME; zinc finger protein NUTCRACKER
STRINGXP_008455492.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF46262951
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G44160.11e-113C2H2-like zinc finger protein
Publications ? help Back to Top
  1. Muñoz-Strale D,León G
    Identification of two highly specific pollen promoters using transcriptomic data.
    Plant Physiol. Biochem., 2014. 83: p. 292-9
    [PMID:25208507]
  2. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]