PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C016840P1
Organism
Cucumis melo
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family AP2
Protein Properties Length: 571aa    MW: 63923.9 Da    PI: 8.0634
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C016840P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP238.33.4e-12238294155
             AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng.krkrfslgkfgtaeeAakaaiaarkkleg 55 
                     s+y+GV++++++gr++A+++d  ++  g  rk  + g ++ +e+Aa+a++ a++k++g
  MELO3C016840P1 238 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqTRKGRQ-GGYDMEEKAARAYDLAALKYWG 294
                     78*******************77776664346655.77******************98 PP
2AP251.62.4e-16337388155
             AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                     s y+GV+++++ grW A+I  +     +k  +lg+fgt eeAa+a++ a+ k++g
  MELO3C016840P1 337 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFGTQEEAAEAYDIAAIKFRG 388
                     57****************988532...5*************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541711.83E-14238303IPR016177DNA-binding domain
PfamPF008471.8E-9238294IPR001471AP2/ERF domain
CDDcd000181.25E-19238302No hitNo description
SMARTSM003801.6E-22239308IPR001471AP2/ERF domain
PROSITE profilePS5103217.425239302IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.106.7E-13239303IPR001471AP2/ERF domain
PRINTSPR003671.1E-6240251IPR001471AP2/ERF domain
CDDcd000185.19E-26337398No hitNo description
SuperFamilySSF541711.11E-17337397IPR016177DNA-binding domain
PfamPF008473.7E-11337388IPR001471AP2/ERF domain
SMARTSM003803.2E-33338402IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.7E-18338397IPR001471AP2/ERF domain
PROSITE profilePS5103218.821338396IPR001471AP2/ERF domain
PRINTSPR003671.1E-6378398IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 571 aa     Download sequence    Send to blast
MAMEASSEPQ QHSHYHHRSQ VTSAVAISNT MSNSFLASHH YNGDFLSVMP LKSDGSLCIM  60
DSINTSQPQE ILPNISPKLE DFLGGATHGK ETTALSLDSI YYNQNAEVGS ERQHSLNLFK  120
QQEQQQHILF HSERYYSGMF QYPAEDPNKE SHIASYCSEI RQDMEQRING CCFGGMNCQD  180
LKPLSLSMSP GSQSSCVTTP SQISQPGPST MEIKKRALAS QKQPVHRKSI DTFGQRTSQY  240
RGVTRHRWTG RYEAHLWDNS CKKEGQTRKG RQGGYDMEEK AARAYDLAAL KYWGSSTHLN  300
FPLKNYELEI EEMKNMNRQE YVAHLRRKSS GFSRGASIYR GVTRHHQHGR WQARIGRVAG  360
NKDLYLGTFG TQEEAAEAYD IAAIKFRGAN AVTNFDTSRY DVERIIASSS LLSGDFARRK  420
KEHKPTNSIE HKEPKQNVTQ TDEGSEISNN LDWRAVFHDN LLLDPSASVE SIDQKSMNSS  480
GYMNHVIGVV ETESCNQEIV NDSKKYKARF SNASSVVSSL SSSRETSPDK SNGSSSVLFA  540
KSPFGNNGSN WLPSPQMRLA PISLPVWNDA *
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818610.0LN681861.1 Cucumis melo genomic scaffold, anchoredscaffold00029.
GenBankLN7132610.0LN713261.1 Cucumis melo genomic chromosome, chr_7.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008452679.10.0PREDICTED: AP2-like ethylene-responsive transcription factor AIL1 isoform X1
SwissprotQ389141e-144ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A1S3BUF30.0A0A1S3BUF3_CUCME; AP2-like ethylene-responsive transcription factor AIL1 isoform X1
STRINGXP_008452679.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF91634114
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-134AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]