PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

ERF

Protein Properties

Length: 276aa MW: 29774.7 Da PI: 5.9248

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C013916P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	62.2	1.2e-19	140	190	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+++AeIrdp +ng +r++lg+f tae+Aa a+++a+ +++g MELO3C013916P1 140 HYRGVRQRP-WGKFAAEIRDPAKNG--ARVWLGTFETAEDAALAYDRAAYRMRG 190 8******.*******9987..***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.730.10	1.8E-32	139	198	IPR001471	AP2/ERF domain
CDD	cd00018	5.58E-32	139	198	No hit	No description
Pfam	PF00847	1.1E-13	140	190	IPR001471	AP2/ERF domain
SMART	SM00380	7.5E-40	140	204	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.88E-23	140	200	IPR016177	DNA-binding domain
PROSITE profile	PS51032	24.197	140	198	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.5E-11	141	152	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.5E-11	164	180	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 276 aa Download sequence Send to blast
MMYGQINGCE SDFVLLETIR RHLLGDSEAF RCGNFSLAGT TSPVFCRSSS FGSLYPCLTE 60 NWGDLPLKED DSEDMLLAGV LRDAVNVGWV PSLETFNFGF SDVKPEPEIL SPVNILPEVK 120 VPSPEVATAL PAVVPAKGKH YRGVRQRPWG KFAAEIRDPA KNGARVWLGT FETAEDAALA 180 YDRAAYRMRG SKALLNFPLR VNSGEPDPVR VTSKRSSPRS SPEPTSSLSS VESGSPKRRK 240 KAEGTAVSTP ELNQLVVGTI GLQVEADVAK CTSGE*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	1e-43	136	205	1	70	ATERF1
3gcc_A	1e-43	136	205	1	70	ATERF1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:9756931}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Also induced by methyl jasmonate (MeJA) independently of JAR1. Ethylene induction is completely dependent on a functional ETHYLENE-INSENSITIVE2 (EIN2), whereas induction by wounding does not need EIN2. Induction by salicylic acid (SA) seems to be independent of PAD4 and NPR1. Transcripts accumulate strongly in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by exogenous abscisic acid (ABA), cold, heat, NaCl or drought stress. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:11950980}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681860	0.0	LN681860.1 Cucumis melo genomic scaffold, anchoredscaffold00021.
GenBank	LN713260	0.0	LN713260.1 Cucumis melo genomic chromosome, chr_6.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008448804.1	0.0	PREDICTED: ethylene-responsive transcription factor 2
Swissprot	O80337	1e-82	EF100_ARATH; Ethylene-responsive transcription factor 1A
TrEMBL	A0A1S3BKJ8	0.0	A0A1S3BKJ8_CUCME; ethylene-responsive transcription factor 2
STRING	XP_008448804.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2239	33	82

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G17500.1	1e-69	ethylene responsive element binding factor 1

Publications ? help Back to Top
Zimmermann P,Hirsch-Hoffmann M,Hennig L,Gruissem W GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox. Plant Physiol., 2004. 136(1): p. 2621-32 [PMID:15375207] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546]