PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

HD-ZIP

Protein Properties

Length: 262aa MW: 29255.8 Da PI: 8.1413

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C005978P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	60	3.8e-19	108	162	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ +++keq +Lee F+++++++ +++ LAk+l+Lt rqV vWFqNrRa+ k MELO3C005978P1 108 RKKLRLSKEQSMVLEETFKEHNTLNPKQKLALAKQLNLTPRQVEVWFQNRRARTK 162 788899***********************************************98 PP
2	HD-ZIP_I/II	127.7	4.8e-41	108	197	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 +kk+rlskeq+ +LEe+F+e+++L+p++K +la++L+l+prqv+vWFqnrRARtk+kq+E+d+e+Lkr++++l+een+rL+kev+eLr +l MELO3C005978P1 108 RKKLRLSKEQSMVLEETFKEHNTLNPKQKLALAKQLNLTPRQVEVWFQNRRARTKLKQTEVDCEYLKRCCENLTEENRRLQKEVQELR-AL 197 69*************************************************************************************9.55 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	2.3E-19	1	81	IPR006712	HD-ZIP protein, N-terminal
Gene3D	G3DSA:1.10.10.60	6.8E-20	91	158	IPR009057	Homeodomain-like
SuperFamily	SSF46689	6.68E-20	94	165	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.734	104	164	IPR001356	Homeobox domain
SMART	SM00389	5.2E-17	106	168	IPR001356	Homeobox domain
Pfam	PF00046	1.5E-16	108	162	IPR001356	Homeobox domain
CDD	cd00086	4.93E-16	108	165	No hit	No description
PROSITE pattern	PS00027	0	139	162	IPR017970	Homeobox, conserved site
Pfam	PF02183	2.0E-11	164	198	IPR003106	Leucine zipper, homeobox-associated
SMART	SM00340	5.7E-27	164	207	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 262 aa Download sequence Send to blast
MGGRDDDLGL TLSLGFGVTT QPTHMQRPSM HNHLRKTSWN ELFQFSDRNA DSRSFLRGID 60 VNRLPTGVDG EEENGVSSPN TEAEAERASC SRGSDDEDGG GGDGDASRKK LRLSKEQSMV 120 LEETFKEHNT LNPKQKLALA KQLNLTPRQV EVWFQNRRAR TKLKQTEVDC EYLKRCCENL 180 TEENRRLQKE VQELRALKLS PQLYMHMNPP TTLTMCPQCE RVAVSSSSST SAATTTRHPA 240 AAGVQRTSMA INPWAVLPIQ R*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	106	112	SRKKLRL
2	156	164	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681848	1e-172	LN681848.1 Cucumis melo genomic scaffold, anchoredscaffold00006.
GenBank	LN713260	1e-172	LN713260.1 Cucumis melo genomic chromosome, chr_6.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008437820.1	1e-161	PREDICTED: homeobox-leucine zipper protein HAT3-like
Swissprot	P46602	1e-99	HAT3_ARATH; Homeobox-leucine zipper protein HAT3
TrEMBL	A0A1S3AUW7	1e-159	A0A1S3AUW7_CUCME; homeobox-leucine zipper protein HAT3-like
STRING	XP_008437820.1	1e-160	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1239	34	105

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G60390.1	2e-79	homeobox-leucine zipper protein 3

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zou LJ, et al. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber mosaic virus. Plant Cell Physiol., 2016. 57(9): p. 1879-89 [PMID:27328697] Caggiano MP, et al. Cell type boundaries organize plant development. Elife, 2018. [PMID:28895530]