PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | MDP0000849944 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
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Family | NAC | ||||||||
Protein Properties | Length: 310aa MW: 35826.9 Da PI: 6.629 | ||||||||
Description | NAC family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | NAM | 173.2 | 7.5e-54 | 5 | 133 | 1 | 128 |
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk...kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 +ppGfrFhPt+eelv +yLk+k+++ +++l +vi ++d+yk+ePwd+++ ++e++ewyfFs++dkky+tg+r+nrat +g+Wkatg+dk+vl MDP0000849944 5 VPPGFRFHPTEEELVGYYLKRKINSLHIDL-DVIVDIDLYKIEPWDIQArcrLGYSEQNEWYFFSHKDKKYPTGTRTNRATVAGFWKATGRDKAVL 99 69****************************.99**************953543344778************************************* PP NAM 94 skkgelvglkktLvfykgrapkgektdWvmheyrl 128 s k++ +g++ktLvfykgrap+g+ktdW+mheyrl MDP0000849944 100 S-KDNIIGMRKTLVFYKGRAPNGNKTDWIMHEYRL 133 *.8899***************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
SuperFamily | SSF101941 | 1.96E-59 | 3 | 154 | IPR003441 | NAC domain |
PROSITE profile | PS51005 | 57.676 | 5 | 154 | IPR003441 | NAC domain |
Pfam | PF02365 | 3.5E-28 | 6 | 133 | IPR003441 | NAC domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0009735 | Biological Process | response to cytokinin | ||||
GO:0009737 | Biological Process | response to abscisic acid | ||||
GO:0009741 | Biological Process | response to brassinosteroid | ||||
GO:0045491 | Biological Process | xylan metabolic process | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0048759 | Biological Process | xylem vessel member cell differentiation | ||||
GO:0050832 | Biological Process | defense response to fungus | ||||
GO:0071365 | Biological Process | cellular response to auxin stimulus | ||||
GO:0090059 | Biological Process | protoxylem development | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding | ||||
GO:0042803 | Molecular Function | protein homodimerization activity | ||||
GO:0043565 | Molecular Function | sequence-specific DNA binding | ||||
GO:0044212 | Molecular Function | transcription regulatory region DNA binding | ||||
GO:0046982 | Molecular Function | protein heterodimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 310 aa Download sequence Send to blast |
MESCVPPGFR FHPTEEELVG YYLKRKINSL HIDLDVIVDI DLYKIEPWDI QARCRLGYSE 60 QNEWYFFSHK DKKYPTGTRT NRATVAGFWK ATGRDKAVLS KDNIIGMRKT LVFYKGRAPN 120 GNKTDWIMHE YRLQTSEHAP PQEEGWVVCR AFKKPSPSHR QGFEAWKHAY VRDHPSSSNF 180 SSEIPMLINP NQGFHQSFGS EEDHFVSNNI FLGNQLMELP QLESPTISTS FVTKEHVLRS 240 NNISTDDYEA ERSNNNSSNQ HIDWRNLDNL LEVQLTDRAS FSHPSLSSAP QNYEQETQNN 300 HLLGCFRDL* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1ut4_A | 3e-48 | 5 | 160 | 17 | 171 | NO APICAL MERISTEM PROTEIN |
1ut4_B | 3e-48 | 5 | 160 | 17 | 171 | NO APICAL MERISTEM PROTEIN |
1ut7_A | 3e-48 | 5 | 160 | 17 | 171 | NO APICAL MERISTEM PROTEIN |
1ut7_B | 3e-48 | 5 | 160 | 17 | 171 | NO APICAL MERISTEM PROTEIN |
4dul_A | 3e-48 | 5 | 160 | 17 | 171 | NAC domain-containing protein 19 |
4dul_B | 3e-48 | 5 | 160 | 17 | 171 | NAC domain-containing protein 19 |
Search in ModeBase |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Predominantly expressed in immature xylem vessels, only in some cells just beside xylem vessels. Also present in various vascular cells of older part of the roots, near the location of emergence of the lateral roots. {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:18445131}. | |||||
Uniprot | TISSUE SPECIFICITY: Expressed in developing protoxylems in roots and shoots (PubMed:16103214, PubMed:16581911, PubMed:17565617, PubMed:18952777). Detected in root protoxylem poles and in vessels of protoxylems, outermost metaxylems, inner metaxylems, shoots and hypocotyls. Expressed in roots, hypocotyls, cotyledons and leaves (PubMed:18445131). Accumulates in the xylem but not in interfascicular fibers or pith cells in inflorescence stems. Present in developing vessels of the secondary xylem in roots undergoing secondary growth (PubMed:18952777). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:16581911, ECO:0000269|PubMed:17565617, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:18952777}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (e.g. genes involved in secondary wall biosynthesis, cell wall modification such as xylan accumulation, and programmed cell death) (PubMed:20935069, PubMed:20488898, PubMed:22037706, PubMed:21284754). Involved in xylem formation in roots and shoots, especially regulating protoxylem vessel differentiation by promoting immature xylem vessel-specific genes expression (PubMed:16103214, PubMed:18445131, PubMed:20488898, PubMed:21498679, PubMed:21284754). Can activate the expression of several genes including XCP1, MYB46, NAC010/SND3, MYB103, MYB58, MYB63, MYB83, KNAT7, ASL19 and ASL20 (PubMed:17890373, PubMed:19088331, PubMed:18952777, PubMed:19122102, PubMed:19808805, PubMed:20935069, PubMed:21284754). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:17890373, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:18952777, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:19122102, ECO:0000269|PubMed:19808805, ECO:0000269|PubMed:20488898, ECO:0000269|PubMed:20935069, ECO:0000269|PubMed:21284754, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22037706}.; FUNCTION: Required for the soilborne fungal pathogen Verticillium longisporum-induced transdifferentiation of chloroplast-containing bundle sheath cells to functional xylem elements leading to stunted growth, vein clearing, and leaf chloroses, as well as xylem hyperplasia within the vasculature of leaves, hypocotyls, and roots due to reinitiation of cambial activity and transdifferentiation of xylem parenchyma cells. This developmental reprogramming mediates also an increased drought stress tolerance. {ECO:0000269|PubMed:23023171}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00017 | PBM | Transfer from AT1G71930 | Download |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: By brassinosteroids (e.g. brassinolide BL), auxin (e.g. 2,4-dichlorphenoxyacetic acid 2,4-D) and cytokinin (e.g. kinetin), with a synergistic effect (PubMed:16103214, PubMed:22345435). Up-regulated in a feed-back loop by ASL20 (PubMed:19088331). Levels are monitored by proteasome-mediated degradation (PubMed:18445131). Repressed by WEE1 upon replication stress to prevent premature tracheary element differentiation (PubMed:21498679). Accumulates during infection by the soilborne fungal pathogen Verticillium longisporum, especially in tissues undergoing de novo xylem formation (PubMed:23023171). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22345435, ECO:0000269|PubMed:23023171}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | KJ919962 | 0.0 | KJ919962.1 Eriobotrya japonica NAC1 transcription factor (NAC1) mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_017184124.1 | 0.0 | NAC domain-containing protein 30-like | ||||
Swissprot | Q9C8W9 | 1e-116 | NAC30_ARATH; NAC domain-containing protein 30 | ||||
TrEMBL | A0A0H3VAL9 | 0.0 | A0A0H3VAL9_9ROSA; NAC1 transcription factor | ||||
STRING | XP_008358342.1 | 0.0 | (Malus domestica) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF7138 | 32 | 47 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G71930.1 | 1e-110 | vascular related NAC-domain protein 7 |
Link Out ? help Back to Top | |
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Phytozome | MDP0000849944 |