PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000286803

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

FAR1

Protein Properties

Length: 854aa MW: 97897.2 Da PI: 6.4575

Description

FAR1 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000286803	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	FAR1	85.2	1e-26	89	191	1	91
FAR1 1 kfYneYAkevGFsvrkskskkskrngeitkrtfvCskegkreeekkk............tekerr....traetrtgCkaklkvkkekdgkwevtk 80 +fY+eYA+++GF++ +++s++sk+++e+++++f Cs++g+++e +k+ + +r+ ++t+Cka+++vk++ dgkw++++ MDP0000286803 89 SFYQEYARSMGFNTAIQNSRRSKTSREFIDAKFACSRYGTKREYDKSynrprarqnkqdP----EnptgRRSCSKTDCKASMHVKRRPDGKWVIHN 180 5****************************************99999999977655443....144559999******************* PP FAR1 81 leleHnHelap 91 +++eHnHel p MDP0000286803 181 FVKEHNHELLP 191 ******975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03101	1.5E-24	89	191	IPR004330	FAR1 DNA binding domain
Pfam	PF10551	3.9E-32	289	381	IPR018289	MULE transposase domain
PROSITE profile	PS50966	9.025	569	605	IPR007527	Zinc finger, SWIM-type
SMART	SM00575	1.1E-6	580	607	IPR006564	Zinc finger, PMZ-type
Pfam	PF04434	6.2E-5	580	603	IPR007527	Zinc finger, SWIM-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 854 aa Download sequence Send to blast
MDIDLRLPSG EHGKEDEEPH EIDNLLEHEE KVHNGDIASE NIEDVRDEVR AEDGGDLNYP 60 TPDMVVFKED TNLEPLFGME FESHGEAYSF YQEYARSMGF NTAIQNSRRS KTSREFIDAK 120 FACSRYGTKR EYDKSYNRPR ARQNKQDPEN PTGRRSCSKT DCKASMHVKR RPDGKWVIHN 180 FVKEHNHELL PAQAVSEQTR KMYAAMARQF AEYKNVVGLK SDPKNPFDKG RNLALEAGDL 240 KILLEFFTQM QSMNSNFFYA VDLGEDQRLK SLFWVDAKSR HDYIHFIDVV SFDTTYVRNK 300 HKMPLALFVG VNQHYQFVLL GCALVSDEST STFSWLMQTW LKAMGGQAPK VIITDHDKSI 360 KSVVVEVFPN AYHCFCLWHI LGKVSENLGH VIKQHESFMA EFEKCIHRSS TNEEFEKRWW 420 EILENFELKE DGWTQLLYED RKQWVPTYMR DVCLAGMSAG QRSDSVNSFF DKYVHKKTTV 480 QEFLKQYEAI LQDRYDEEAK ADYDTWNKPP TLRSPSPLEK SVSGLYTHAV FKKIQGEVLG 540 AVACHPKRER QDETGTIFKV QDFEKNEDFI VTWNEMKTEV SCVCCLFEYK GYLCRHALIV 600 LQICGLSAIP SHYVLKRWTK DAKNRHLVGE DSDIVPSRVQ KFNDLCQRAM KVIEEGTLSQ 660 ESYSVACRAL EEAFGNCVSV NNSSKSLLEA GTSVTHGLLC IEDDNQNRSM SSKTNKKKNP 720 TKKRKVNSEP EVMAVGAQDS LQPMEKLNSR AVTLDGYYAA QPNVQGMVQL NLMAPTRDNY 780 YGNQQTIQGL GQLNSIAPSH DGYYSAQQSM HGLGQMDFFR TPTGYAYGIR VSLLDMDDPN 840 VRTAPLHEDA SRHA

Sequence ? help Back to Top

Protein Sequence Length: 854 aa Download sequence Send to blast

MDIDLRLPSG EHGKEDEEPH EIDNLLEHEE KVHNGDIASE NIEDVRDEVR AEDGGDLNYP  60
TPDMVVFKED TNLEPLFGME FESHGEAYSF YQEYARSMGF NTAIQNSRRS KTSREFIDAK  120
FACSRYGTKR EYDKSYNRPR ARQNKQDPEN PTGRRSCSKT DCKASMHVKR RPDGKWVIHN  180
FVKEHNHELL PAQAVSEQTR KMYAAMARQF AEYKNVVGLK SDPKNPFDKG RNLALEAGDL  240
KILLEFFTQM QSMNSNFFYA VDLGEDQRLK SLFWVDAKSR HDYIHFIDVV SFDTTYVRNK  300
HKMPLALFVG VNQHYQFVLL GCALVSDEST STFSWLMQTW LKAMGGQAPK VIITDHDKSI  360
KSVVVEVFPN AYHCFCLWHI LGKVSENLGH VIKQHESFMA EFEKCIHRSS TNEEFEKRWW  420
EILENFELKE DGWTQLLYED RKQWVPTYMR DVCLAGMSAG QRSDSVNSFF DKYVHKKTTV  480
QEFLKQYEAI LQDRYDEEAK ADYDTWNKPP TLRSPSPLEK SVSGLYTHAV FKKIQGEVLG  540
AVACHPKRER QDETGTIFKV QDFEKNEDFI VTWNEMKTEV SCVCCLFEYK GYLCRHALIV  600
LQICGLSAIP SHYVLKRWTK DAKNRHLVGE DSDIVPSRVQ KFNDLCQRAM KVIEEGTLSQ  660
ESYSVACRAL EEAFGNCVSV NNSSKSLLEA GTSVTHGLLC IEDDNQNRSM SSKTNKKKNP  720
TKKRKVNSEP EVMAVGAQDS LQPMEKLNSR AVTLDGYYAA QPNVQGMVQL NLMAPTRDNY  780
YGNQQTIQGL GQLNSIAPSH DGYYSAQQSM HGLGQMDFFR TPTGYAYGIR VSLLDMDDPN  840
VRTAPLHEDA SRHA

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.24731	1e-102	fruit

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that recognizes and binds to the DNA consensus sequence 5'-CACGCGC-3'. Activates the expression of FHY1 and FHL involved in light responses. When associated with PHYA, protects it from being recognized and degraded by the COP1/SPA complex. Positive regulator of chlorophyll biosynthesis via the activation of HEMB1 gene expression. {ECO:0000269\|PubMed:11889039, ECO:0000269\|PubMed:12753585, ECO:0000269\|PubMed:17012604, ECO:0000269\|PubMed:18033885, ECO:0000269\|PubMed:18715961, ECO:0000269\|PubMed:22634759}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated after exposure to far-red light. Subject to a negative feedback regulation by PHYA signaling. Up-regulated by white light. {ECO:0000269\|PubMed:11889039, ECO:0000269\|PubMed:18033885, ECO:0000269\|PubMed:22634759}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008378341.1	0.0	protein FAR-RED ELONGATED HYPOCOTYL 3 isoform X1
Refseq	XP_008378342.1	0.0	protein FAR-RED ELONGATED HYPOCOTYL 3 isoform X1
Swissprot	Q9LIE5	0.0	FHY3_ARATH; Protein FAR-RED ELONGATED HYPOCOTYL 3
TrEMBL	A0A251Q297	0.0	A0A251Q297_PRUPE; Uncharacterized protein
STRING	XP_008378341.1	0.0	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF40	30	530

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G22170.2	0.0	far-red elongated hypocotyls 3

Link Out ? help Back to Top
Phytozome	MDP0000286803

Publications ? help Back to Top
Chang N,Gao Y,Zhao L,Liu X,Gao H Arabidopsis FHY3/CPD45 regulates far-red light signaling and chloroplast division in parallel. Sci Rep, 2015. 5: p. 9612 [PMID:25872642] Wang C, et al. SCAB3 Is Required for Reorganization of Actin Filaments during Light Quality Changes. J Genet Genomics, 2015. 42(4): p. 161-8 [PMID:25953354] Wang W, et al. A pair of light signaling factors FHY3 and FAR1 regulates plant immunity by modulating chlorophyll biosynthesis. J Integr Plant Biol, 2016. 58(1): p. 91-103 [PMID:25989254] Ma L, et al. Arabidopsis FHY3 and FAR1 Regulate Light-Induced myo-Inositol Biosynthesis and Oxidative Stress Responses by Transcriptional Activation of MIPS1. Mol Plant, 2016. 9(4): p. 541-57 [PMID:26714049] Siddiqui H,Khan S,Rhodes BM,Devlin PF FHY3 and FAR1 Act Downstream of Light Stable Phytochromes. Front Plant Sci, 2016. 7: p. 175 [PMID:26941752] Li D, et al. FAR-RED ELONGATED HYPOCOTYL3 activates SEPALLATA2 but inhibits CLAVATA3 to regulate meristem determinacy and maintenance in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9375-80 [PMID:27469166] Liu L,Li B,Liu X FAR-RED ELONGATED HYPOCOTYL3 promotes floral meristem determinacy in Arabidopsis. Plant Signal Behav, 2016. 11(10): p. e1238545 [PMID:27660915] Ma L,Xue N,Fu X,Zhang H,Li G Arabidopsis thaliana FAR-RED ELONGATED HYPOCOTYLS3 (FHY3) and FAR-RED-IMPAIRED RESPONSE1 (FAR1) modulate starch synthesis in response to light and sugar. New Phytol., 2017. 213(4): p. 1682-1696 [PMID:27859295] Liu Y, et al. Light and Ethylene Coordinately Regulate the Phosphate Starvation Response through Transcriptional Regulation of PHOSPHATE STARVATION RESPONSE1. Plant Cell, 2017. 29(9): p. 2269-2284 [PMID:28842534] Joly-Lopez Z, et al. Abiotic Stress Phenotypes Are Associated with Conserved Genes Derived from Transposable Elements. Front Plant Sci, 2017. 8: p. 2027 [PMID:29250089]