PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000253576
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family bHLH
Protein Properties Length: 708aa    MW: 81415.4 Da    PI: 6.7305
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000253576genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH12.50.000265695863855
                    STCHHHHHHHHHHHHHHH CS
            HLH  38 lsKaeiLekAveYIksLq 55 
                    ++Ka+i+e A+ YI++Lq
  MDP0000253576 569 MNKATIVEDAITYIQELQ 586
                    69***************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF482394.16E-5114187IPR008930Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
PfamPF013972.7E-4618168IPR001906Terpene synthase, N-terminal domain
Gene3DG3DSA:1.50.30.106.2E-5325209IPR001906Terpene synthase, N-terminal domain
SuperFamilySSF485769.5E-69201449IPR008949Isoprenoid synthase domain
PfamPF039361.1E-65205406IPR005630Terpene synthase, metal-binding domain
Gene3DG3DSA:1.10.600.101.1E-71213394IPR008949Isoprenoid synthase domain
Gene3DG3DSA:1.10.600.102.6E-13395455IPR008949Isoprenoid synthase domain
Gene3DG3DSA:4.10.280.105.1E-7569601IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008152Biological Processmetabolic process
GO:0000287Molecular Functionmagnesium ion binding
GO:0010333Molecular Functionterpene synthase activity
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 708 aa     Download sequence    Send to blast
MEHPCAQDGI ICFQHEQKLD DLRSALKKVG GQAVEGLDMI DAVQRLGIDY HFEDEIDQIL  60
QKQHIISSTT AHGAHDPTDL HEVALRFRLL RQHGYFVSDD VFNNFKEGEG NFNQMLSEDI  120
KGLMSLYEAS KLSTEGEVVL EEAGKFSGHF LNSSLLHLDH HQARVVENTL RNPHHKSLAP  180
FMAKNFFVSG FQGTYNRWLN ILQTVAKTDL YMVQSLHQKE VVQVSKWWEE LGLSKELKFA  240
RDQPIKWYNW SMAGLTNPNL SDERIEFTKS VSFIYLIDDI FDVYGTLDDL TLFTEVVNRW  300
EIGAIEHLPD YMKICFKALY DMTDEISCKV YEKHGWNPLH SLKKTWASLC NAFLVEAKWF  360
KSGHLPRAEE YLKNGIISSG VNVMLVHIFF LLGEGKTMEE AQEHVTNMIS QEWKKLNKVL  420
VSPNPFPAAF TKASLNLXRM VPLMYSYDDN QRLPSLDDAR QLPTPGGTRS RESWRCGPAT  480
GRRRTPFPGS TKRRIRHRFG SRGLRRIGPR RRSRFRRHHR HRSLSSGMSE SRCRRGEEEG  540
DTGDQQNGGV QLEWEHWSPL FMVGVWYSMN KATIVEDAIT YIQELQQKVN FLKDQLFEME  600
ESSEETLQPN KEETHAAEEM KKFGIQTEVN VTKIDGNKLW VKTVLEKKRG GFTKLMEAMT  660
GFGFELTDTS VTTSNGVMMV SSCITGFCCD KLEVEQTREL MLEIINGI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3n0f_A3e-803745468534Isoprene synthase
3n0f_B3e-803745468534Isoprene synthase
3n0g_A3e-803745468534Isoprene synthase
3n0g_B3e-803745468534Isoprene synthase
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.138260.0fruit| leaf
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Up-regulated during fruit ripening. {ECO:0000269|PubMed:15522848}.
UniprotTISSUE SPECIFICITY: Expressed in receptacle tissue. Not detected in leaves or green fruit. {ECO:0000269|PubMed:15522848}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in monoterpene (C10) and sesquiterpene (C15) biosynthesis. Converts geranyl diphosphate (GPP) into S-linalool and farnesyl diphosphate (FPP) into (3S)-E-nerolidol. Exclusively present and highly expressed in the fruit of cultivated (octaploid) varieties. {ECO:0000269|PubMed:14630967, ECO:0000269|PubMed:15522848}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankJX8487340.0JX848734.1 Malus x domestica linalool synthase (LIS) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028965149.10.0(3S,6E)-nerolidol synthase 1-like
SwissprotP0CV940.0NES1_FRAAN; (3S,6E)-nerolidol synthase 1
TrEMBLL0I7G30.0L0I7G3_MALDO; Linalool synthase
STRINGXP_008383955.10.0(Malus domestica)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G21330.11e-30bHLH family protein
Publications ? help Back to Top
  1. Aharoni A, et al.
    Terpenoid metabolism in wild-type and transgenic Arabidopsis plants.
    Plant Cell, 2003. 15(12): p. 2866-84
    [PMID:14630967]
  2. Aharoni A, et al.
    Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species.
    Plant Cell, 2004. 16(11): p. 3110-31
    [PMID:15522848]