PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000252726
Organism
Malus domestica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family B3
Protein Properties Length: 820aa    MW: 91271.7 Da    PI: 9.7465
Description B3 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000252726genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B351.42e-165185981499
                    T-EE--HHH.HTT---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEEEE-S CS
             B3  14 grlvlpkkfaeehggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelvvkvfrk 99 
                    gr ++p +f++++ +      +  l+ ++g + +v++  + + +++++++GW++Fvk+++L++gD +vF +dg+++f  +vk++++
  MDP0000252726 518 GRXRIPPTFVRKNFNRRSL-SKCDLKGPTGIRRTVEF--EDRENGIFFRNGWQGFVKDHHLEAGDLLVFDYDGETKF--NVKIYDR 598
                    7889*********666444.49***************..99999***************************998888..9999987 PP
2B339.78.7e-13711799899
                    -HHHHTT-EE--HHH.HTT---..--SEEEEEETTS-EEEEEE..EEETTE..EEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEEEE-S CS
             B3   8 sdvlksgrlvlpkkfaeehggkkeesktltledesgrsWevkliyrkksgr..yvltkGWkeFvkangLkegDfvvFkldgrsefelvvkvfrk 99 
                    + +l ++ +++pk+ a + g+    + t+t +d+ grsW ++l++r+ s++    + +GW + vkan++  gD+++F +++  ++ ++v++f+k
  MDP0000252726 711 KKHLLQC-VRIPKQLAVAEGLMY--KNTVTXQDPXGRSWLIQLRIRRXSSTdhLDIXTGWTDCVKANRISPGDTMIFXFVK--QGLMRVHIFKK 799
                    4444445.99*****99997663..459***************99777777678899*********************765..67789999986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd131329.93E-16438451No hitNo description
PfamPF015541.2E-3248207IPR002528Multi antimicrobial extrusion protein
PfamPF015548.4E-17301410IPR002528Multi antimicrobial extrusion protein
CDDcd100172.20E-14505597No hitNo description
PROSITE profilePS5086311.843505599IPR003340B3 DNA binding domain
SuperFamilySSF1019361.26E-17506601IPR015300DNA-binding pseudobarrel domain
SMARTSM010196.1E-15506599IPR003340B3 DNA binding domain
Gene3DG3DSA:2.40.330.104.3E-18508601IPR015300DNA-binding pseudobarrel domain
PfamPF023622.5E-14517598IPR003340B3 DNA binding domain
SuperFamilySSF1019361.16E-14698799IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.4E-14699799IPR015300DNA-binding pseudobarrel domain
SMARTSM010191.6E-7705800IPR003340B3 DNA binding domain
PfamPF023622.4E-10715799IPR003340B3 DNA binding domain
CDDcd100172.77E-8719798No hitNo description
PROSITE profilePS5086311.632720800IPR003340B3 DNA binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006855Biological Processdrug transmembrane transport
GO:0016020Cellular Componentmembrane
GO:0003677Molecular FunctionDNA binding
GO:0015238Molecular Functiondrug transmembrane transporter activity
GO:0015297Molecular Functionantiporter activity
Sequence ? help Back to Top
Protein Sequence    Length: 820 aa     Download sequence    Send to blast
MDXGDMVANT NNTTPLLEGG GHGGAKGGWW NKVLDVEEAK NQVLFSLPMI LTNVCYYMIP  60
LISVMFAGHL GELQLAGATL ANSWATVTGF AFMVGLSGAL ETLCGQGFGA KLYRMLGIYL  120
QASSIISFLA SIIVSVVWFY TEPILILIHQ DPQISKYAAL YMKFLIPGLF AYGFLHNILR  180
FLQTQSVVIP LVYFSVIPVV LHVGIAYGLV HWTGLGYVGA PVAASISIWI SMLXLATYVL  240
CAKKFEHTWE GFTLESFHYV LPNLKLALPS AAMVCLEYWA FEILVFMAGV MPKAEQNTSL  300
IAICTRVSNE LGAGNPEKAK NAMAVTLKLS ILLALIVDLA LAFGHNLWAG AFSDSSVIIK  360
LFASMTPLLL ISILADSVQG VLSGVARGCG WQHLAVYVNL GTFYLVGMTI AGVLAFKLKL  420
YAKGLWIGLI CGLSCQTVLL LVVTLRTKWT QLDLPRNADA VLRKIVSGCW RRCMHVSINW  480
LFWQSISHSR AHPLITDSLG PMLTLIVKRL STGCRQIGRX RIPPTFVRKN FNRRSLSKCD  540
LKGPTGIRRT VEFEDRENGI FFRNGWQGFV KDHHLEAGDL LVFDYDGETK FNVKIYDRSA  600
CEKDXEAAKM NXVNQARVKD ENVDVATGNY NKERKIRTTS RSSKLSSVLV LCIWRRFVSD  660
ILPCFHSLIR VSDSVGKYLI SRKRRYYVED TSTGSVLLKS ENQCFLAFSN KKHLLQCVRI  720
PKQLAVAEGL MYKNTVTXQD PXGRSWLIQL RIRRXSSTDH LDIXTGWTDC VKANRISPGD  780
TMIFXFVKQG LMRVHIFKKG AVRGNKCRVV LADPNVKAES
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5yck_A7e-883846712455multi drug efflux transporter
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the root epidermis and cortex. Not expressed in hypocotyl. Detected in the elongation zone of young roots, but not in the meristematic region. {ECO:0000269|PubMed:11449055}.
Functional Description ? help Back to Top
Source Description
UniProtRequired for protection of the roots from inhibitory compounds. When expressed in a heterologous system, confers resistance to tetramethylammonium chloride. {ECO:0000269|PubMed:11449055}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028956074.10.0protein DETOXIFICATION 19-like
RefseqXP_028956075.10.0protein DETOXIFICATION 19-like
SwissprotQ9LUH20.0DTX19_ARATH; Protein DETOXIFICATION 19
TrEMBLA0A498KB200.0A0A498KB20_MALDO; Protein DETOXIFICATION
STRINGXP_009356787.10.0(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF116023
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G01580.11e-11B3 family protein
Publications ? help Back to Top
  1. Diener AC,Gaxiola RA,Fink GR
    Arabidopsis ALF5, a multidrug efflux transporter gene family member, confers resistance to toxins.
    Plant Cell, 2001. 13(7): p. 1625-38
    [PMID:11449055]
  2. Li L,He Z,Pandey GK,Tsuchiya T,Luan S
    Functional cloning and characterization of a plant efflux carrier for multidrug and heavy metal detoxification.
    J. Biol. Chem., 2002. 277(7): p. 5360-8
    [PMID:11739388]
  3. Hvorup RN, et al.
    The multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily.
    Eur. J. Biochem., 2003. 270(5): p. 799-813
    [PMID:12603313]
  4. Marinova K, et al.
    The Arabidopsis MATE transporter TT12 acts as a vacuolar flavonoid/H+ -antiporter active in proanthocyanidin-accumulating cells of the seed coat.
    Plant Cell, 2007. 19(6): p. 2023-38
    [PMID:17601828]