PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

MIKC_MADS

Protein Properties

Length: 231aa MW: 26179.3 Da PI: 10.1036

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000250080	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	99.1	1.8e-31	25	74	1	50
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeys 50 krien++nrqvtf+kRrng+lKKA+ELSvLCdaeva+i+fs++g+lyey+ MDP0000250080 25 KRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSNRGRLYEYA 74 79***********************************************8 PP
2	K-box	79.9	6.1e-27	93	183	4	94
K-box 4 ssgksleeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaL 94 s++ s++ea ++++qqe akL+++i nLq+ +R+++G+ L+s+ +k+L++Le++Lek++++iRskK+ l+++ + l+ k e+++ ++++ MDP0000250080 93 SNTGSVSEASTQYYQQEXAKLRAQIGNLQNANRNMMGDALSSMPIKDLKSLESKLEKGISRIRSKKELDLHNNNQLLRAKIAENERGQQNI 183 4444599*************************************************************************99998877765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50066	33.613	17	77	IPR002100	Transcription factor, MADS-box
SMART	SM00432	7.1E-41	17	76	IPR002100	Transcription factor, MADS-box
CDD	cd00265	4.79E-45	18	94	No hit	No description
SuperFamily	SSF55455	3.79E-33	18	91	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	5.3E-33	19	39	IPR002100	Transcription factor, MADS-box
PROSITE pattern	PS00350	0	19	73	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	1.1E-26	26	73	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	5.3E-33	39	54	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	5.3E-33	54	75	IPR002100	Transcription factor, MADS-box
Pfam	PF01486	6.7E-19	100	180	IPR002487	Transcription factor, K-box
PROSITE profile	PS51297	11.6	103	189	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 231 aa Download sequence Send to blast
MANENKSLSI DSPQRKLGRG KIEIKRIENT TNRQVTFCKR RNGLLKKAYE LSVLCDAEVA 60 LIVFSNRGRL YEYANNSVKA TVERYKKTCA DSSNTGSVSE ASTQYYQQEX AKLRAQIGNL 120 QNANRNMMGD ALSSMPIKDL KSLESKLEKG ISRIRSKKEL DLHNNNQLLR AKIAENERGQ 180 QNINVMAGGG TSSYDILQSQ PYDSRNYFQV NALQPNHQYN PRHDQISLQL V

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1tqe_P	3e-20	17	85	1	69	Myocyte-specific enhancer factor 2B
1tqe_Q	3e-20	17	85	1	69	Myocyte-specific enhancer factor 2B
1tqe_R	3e-20	17	85	1	69	Myocyte-specific enhancer factor 2B
1tqe_S	3e-20	17	85	1	69	Myocyte-specific enhancer factor 2B
5f28_A	4e-20	17	85	1	69	MEF2C
5f28_B	4e-20	17	85	1	69	MEF2C
5f28_C	4e-20	17	85	1	69	MEF2C
5f28_D	4e-20	17	85	1	69	MEF2C
6byy_A	4e-20	17	85	1	69	MEF2 CHIMERA
6byy_B	4e-20	17	85	1	69	MEF2 CHIMERA
6byy_C	4e-20	17	85	1	69	MEF2 CHIMERA
6byy_D	4e-20	17	85	1	69	MEF2 CHIMERA
6c9l_A	3e-20	17	85	1	69	Myocyte-specific enhancer factor 2B
6c9l_B	3e-20	17	85	1	69	Myocyte-specific enhancer factor 2B
6c9l_C	3e-20	17	85	1	69	Myocyte-specific enhancer factor 2B
6c9l_D	3e-20	17	85	1	69	Myocyte-specific enhancer factor 2B
6c9l_E	3e-20	17	85	1	69	Myocyte-specific enhancer factor 2B
6c9l_F	3e-20	17	85	1	69	Myocyte-specific enhancer factor 2B
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.699	0.0	bud\| cell culture\| fruit\| leaf

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in regulating genes that determines stamen and carpel development in wild-type flowers. {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP164009	0.0	KP164009.1 Pyrus pyrifolia clone PpAG-4 AG MADS-box protein mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008371525.2	1e-165	floral homeotic protein AGAMOUS-like isoform X1
Refseq	XP_008371527.2	1e-165	floral homeotic protein AGAMOUS-like isoform X2
Refseq	XP_008371528.2	1e-165	floral homeotic protein AGAMOUS-like isoform X3
Swissprot	Q40168	1e-114	AG_SOLLC; Floral homeotic protein AGAMOUS
TrEMBL	A0A498JT07	1e-164	A0A498JT07_MALDO; Uncharacterized protein
STRING	XP_008371525.1	1e-165	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF684	29	102

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G18960.1	1e-101	MIKC_MADS family protein

Link Out ? help Back to Top
Phytozome	MDP0000250080

Publications ? help Back to Top
Pan IL,McQuinn R,Giovannoni JJ,Irish VF Functional diversification of AGAMOUS lineage genes in regulating tomato flower and fruit development. J. Exp. Bot., 2010. 61(6): p. 1795-806 [PMID:20335407] Gimenez E, et al. TOMATO AGAMOUS1 and ARLEQUIN/TOMATO AGAMOUS-LIKE1 MADS-box genes have redundant and divergent functions required for tomato reproductive development. Plant Mol. Biol., 2016. 91(4-5): p. 513-31 [PMID:27125648]