PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | MDP0000249969 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
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Family | bHLH | ||||||||
Protein Properties | Length: 1084aa MW: 117981 Da PI: 6.1633 | ||||||||
Description | bHLH family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | HLH | 31.8 | 2.5e-10 | 77 | 123 | 3 | 54 |
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++h+e+ErrRR+riN +++Lr l+P +K++Ka+ L ++ +k+L MDP0000249969 77 KNHSEAERRRRERINAHLSTLRGLVPCT-----EKMDKATLLAAVISQVKEL 123 58*************************8.....7********9999888777 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
PROSITE profile | PS50888 | 15.129 | 74 | 123 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam | PF00010 | 3.8E-8 | 77 | 123 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Gene3D | G3DSA:4.10.280.10 | 4.1E-12 | 78 | 125 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SuperFamily | SSF47459 | 1.03E-11 | 78 | 125 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SMART | SM00353 | 2.4E-10 | 80 | 129 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Gene3D | G3DSA:3.30.70.260 | 2.8E-4 | 161 | 222 | No hit | No description |
CDD | cd04873 | 4.61E-6 | 161 | 217 | No hit | No description |
Pfam | PF16420 | 2.2E-86 | 280 | 559 | IPR032197 | Ubiquitin-like modifier-activating enzyme Atg7, N-terminal |
Gene3D | G3DSA:3.40.50.720 | 1.3E-41 | 581 | 760 | IPR016040 | NAD(P)-binding domain |
SuperFamily | SSF69572 | 1.44E-42 | 596 | 756 | IPR000594 | THIF-type NAD/FAD binding fold |
Pfam | PF00899 | 1.0E-39 | 596 | 892 | IPR000594 | THIF-type NAD/FAD binding fold |
CDD | cd01486 | 2.50E-167 | 609 | 926 | No hit | No description |
SuperFamily | SSF69572 | 1.44E-42 | 790 | 921 | IPR000594 | THIF-type NAD/FAD binding fold |
Gene3D | G3DSA:3.40.50.720 | 1.3E-41 | 793 | 894 | IPR016040 | NAD(P)-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0010150 | Biological Process | leaf senescence | ||||
GO:0050832 | Biological Process | defense response to fungus | ||||
GO:0005829 | Cellular Component | cytosol | ||||
GO:0008641 | Molecular Function | small protein activating enzyme activity | ||||
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 1084 aa Download sequence Send to blast |
MDYYSFNSKS SFGSDFSSLF DPFKHDVSGF GGALRGGAAA KLPHSLVLDS EKGELVKAPA 60 RVGKKELPEA KALLALKNHS EAERRRRERI NAHLSTLRGL VPCTEKMDKA TLLAAVISQV 120 KELKKDALES SKGFLIPVDA DEVKIEPYVA AGDGTISVKA SVCCEYRSEL LSDLREALDS 180 LHLKIVKAEI ATLGNRVKNV FVLTSSKPGS NDSDAEAYEL LASSVHQVLS SXLDKASASP 240 EYSPRTTLPS KRRRLSYFDK IDTSSSSSKI MERGSGKSIL QFAPFQSSVD EGFWHRLSSL 300 KLNKFGIDDS PVPITGFYAP CSHSQVSNHL TLLAESLPSD SSEESSVTGV SRGNRNRCSV 360 PGIIYNTNTV EGFHALDKQG LLKAEAQKIW KDIQSGRALE DSSVLXRFLV ISFADLKKWS 420 FNYWFAFPAL VLDPPATLVN LRPASXCFSS XEAESVSAAF NEWRNSSLTA DVPFFLVHLD 480 SNSHATIKHL KDWETSQSAD DGHKLLFGFY DPCHLPNHPX WPLRNLLALI CSRWDLKSVH 540 FLCYRESRGF ADLGLSLVGE ALITVPPGSA AEIGLAISAA DLNLKLMRWR ALPSLNLNSL 600 SSLKCLLLGA GTLGCQVART LMAWGVRTIT LVDNGRVAMS NPLRQSLYTL DDCLNGGEFK 660 VTAAVNSLKK IFPAVEAEGV IMAIPMPGHP VPSQEEQSVL DDCGRLHDLI DCHDVVFLLT 720 DTRESRWLPS LLCANTNKIT ITAALGFDSF LVMRHGAGPC SSSHDSKTEA ENALSAYMGN 780 LGLTDRDGGK RLGCYFCNDV VAPIDSTSNR TLDQQCTVTR PGLAPIASAL AVELLVGILH 840 HPHGIFAEGE VVNCSNSRSS EQPLGILPHQ IRGSLAQFSQ MTLVGHSSDS CTACCSTVVS 900 EYRKRGMEFI LQAINHPTYL EDLTGLTELM KSASKFELDW DDGTDEDDDD LVEPANLQLC 960 VRASPRTLAT GNAKTSFLED VLRVHDFLID PSXIRAHHDG KTVQVAPLPP LFPQXVMSSA 1020 VGDGYATAIV DDEXXVAAAS XQAKRAALXR KAAXDMVAAE DFARRFESGY XSDISRGVVV 1080 EEQA |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
3vx8_A | 1e-143 | 279 | 572 | 8 | 297 | Ubiquitin-like modifier-activating enzyme atg7 |
3vx8_D | 1e-143 | 279 | 572 | 8 | 297 | Ubiquitin-like modifier-activating enzyme atg7 |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 82 | 87 | ERRRRE |
2 | 250 | 254 | KRRRL |
Expression -- UniGene ? help Back to Top | ||||||
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UniGene ID | E-value | Expressed in | ||||
Mdo.8157 | 0.0 | fruit| leaf |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Up-regulated during leaf senescence. {ECO:0000269|PubMed:12070171}. | |||||
Uniprot | TISSUE SPECIFICITY: Constitutively expressed (at protein level). {ECO:0000269|PubMed:12070171}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes. Involved in the senescence process (PubMed:12070171). Involved in the degradation of damaged peroxisomes (PubMed:24368788). Involved in the non-selective degradation of chlorophylls and photosynthetic proteins during stress-induced leaf yellowing (PubMed:24510943). {ECO:0000269|PubMed:12070171, ECO:0000269|PubMed:24368788, ECO:0000269|PubMed:24510943}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | KF438035 | 0.0 | KF438035.1 Malus domestica autophagy-related protein 7b (ATG7b) mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | NP_001315925.1 | 0.0 | ubiquitin-like modifier-activating enzyme atg7 | ||||
Swissprot | Q94CD5 | 0.0 | ATG7_ARATH; Ubiquitin-like modifier-activating enzyme atg7 | ||||
TrEMBL | A0A498ISP6 | 0.0 | A0A498ISP6_MALDO; Uncharacterized protein | ||||
STRING | XP_008383635.1 | 0.0 | (Malus domestica) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G41130.1 | 2e-28 | bHLH family protein |
Link Out ? help Back to Top | |
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Phytozome | MDP0000249969 |