PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MDP0000232445

Organism

Malus domestica

Taxonomic ID

3750

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

DBB

Protein Properties

Length: 299aa MW: 32926.2 Da PI: 4.7757

Description

DBB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000232445	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-B_box	21.9	3.5e-07	4	44	5	39
zf-B_box 5 kCpeHeekelqlfCedCqqllCedClleeHkg......Htv 39 C+ +e+ +++ C ++ lC++C +e H H++ MDP0000232445 4 QCDVCEKAPATVICCADEAALCAKCDVEVHAAnklaskHQR 44 7*****************************65667777765 PP
2	zf-B_box	26.4	1.5e-08	53	94	2	37
zf-B_box 2 eerkCpeHeekelqlfCedCqqllCedClleeHkg......H 37 + +kC+ +++k + +fC +++ l+C+dC + +H+ H MDP0000232445 53 KLPKCDICQDKIAFIFCVEDRALFCQDCDEPIHSAnslsanH 94 789******9*******************655666666 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50119	9.3	1	47	IPR000315	B-box-type zinc finger
CDD	cd00021	2.10E-7	3	47	No hit	No description
Pfam	PF00643	2.8E-5	4	44	IPR000315	B-box-type zinc finger
SMART	SM00336	8.9E-10	4	47	IPR000315	B-box-type zinc finger
PROSITE profile	PS50119	8.859	52	99	IPR000315	B-box-type zinc finger
Pfam	PF00643	1.5E-7	52	95	IPR000315	B-box-type zinc finger
SMART	SM00336	6.7E-16	52	99	IPR000315	B-box-type zinc finger
CDD	cd00021	3.57E-7	55	98	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005622	Cellular Component	intracellular
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 299 aa Download sequence Send to blast
MKIQCDVCEK APATVICCAD EAALCAKCDV EVHAANKLAS KHQRLLLQSL SNKLPKCDIC 60 QDKIAFIFCV EDRALFCQDC DEPIHSANSL SANHQRFLAT GIRVPLASSS TKEAETSSLE 120 PSNQGAQKIS TKVSAPQASG ISSPWGVDDL LQLSDFESSD KNSMVSIEHV ETALKDAPEL 180 TLFLLKDQRN GRYHNIRGSQ VVCLFFHLSL TLRNSGLCFL QKDSLEFGEL EWIADMGIFG 240 DQYPQEAPAA AEVPQLPAPE SSNFTSYRPP KSSSPQKKPR IEIPDDDDEY FTVPDLGRF

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.15481	0.0	bud\| leaf\| stem

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: High expression in leaves and lower in roots and flowers.

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of seedling photomorphogenesis and light-regulated inhibition of hypocotyl elongation (PubMed:17605755, PubMed:18540109, PubMed:21685177). BBX24/STO and BBX25/STH function as transcriptional corepressors of HY5 activity, leading to the down-regulation of BBX22 expression. BBX24/STO acts additively with BBX25/STH during de-etiolation and the hypocotyl shade avoidance response (PubMed:23624715). Functions as negative regulator of photomorphogenic UV-B responses by interacting with both COP1 and HY5 (PubMed:22410790). May act as a transcription factor in the salt-stress response (PubMed:12909688). {ECO:0000269\|PubMed:12909688, ECO:0000269\|PubMed:17605755, ECO:0000269\|PubMed:18540109, ECO:0000269\|PubMed:21685177, ECO:0000269\|PubMed:22410790, ECO:0000269\|PubMed:23624715}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian regulation with a peak before dawn. {ECO:0000269\|PubMed:17605755}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_007223811.1	1e-125	B-box zinc finger protein 24
Refseq	XP_008222603.1	1e-125	PREDICTED: B-box zinc finger protein 24-like
Swissprot	Q96288	5e-78	BBX24_ARATH; B-box zinc finger protein 24
TrEMBL	A0A314UGU9	1e-123	A0A314UGU9_PRUYE; B-box zinc finger protein 24-like
STRING	XP_008222603.1	1e-124	(Prunus mume)
STRING	EMJ25010	1e-124	(Prunus persica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3438	31	57

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G06040.2	2e-66	DBB family protein

Link Out ? help Back to Top
Phytozome	MDP0000232445

Publications ? help Back to Top
Gangappa SN,Holm M,Botto JF Molecular interactions of BBX24 and BBX25 with HYH, HY5 HOMOLOG, to modulate Arabidopsis seedling development. Plant Signal Behav, 2014. [PMID:23733077] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Imtiaz M, et al. Identification and functional characterization of the BBX24 promoter and gene from chrysanthemum in Arabidopsis. Plant Mol. Biol., 2015. 89(1-2): p. 1-19 [PMID:26253592] Job N,Yadukrishnan P,Bursch K,Datta S,Johansson H Two B-Box Proteins Regulate Photomorphogenesis by Oppositely Modulating HY5 through their Diverse C-Terminal Domains. Plant Physiol., 2018. 176(4): p. 2963-2976 [PMID:29439209]