PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus

Family

MIKC_MADS

Protein Properties

Length: 299aa MW: 34761.3 Da PI: 9.2856

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MDP0000218020	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	93	1.4e-29	9	59	1	51
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51 krienk+nrqvtfskR g+lKKA+E+SvLCdaeva+i+fs++gkl+eys+ MDP0000218020 9 KRIENKINRQVTFSKRTSGLLKKAHEISVLCDAEVALIVFSTKGKLFEYST 59 79***********************************************96 PP
2	K-box	99.1	6.2e-33	112	198	14	100
K-box 14 aeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkklee 100 +++ e+akLk+++e Lqr+q h++GedL+ Ls++eLq+LeqqL+++l++iRs+Kn++++e+i+elqkk k+lqe+n+ L k+++e MDP0000218020 112 KGNWTLEHAKLKARVEVLQRNQSHYMGEDLQILSFQELQNLEQQLDSALRRIRSRKNQVMYESISELQKKDKALQEQNNLLAKNVKE 198 5699******************************************************************************99886 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50066	31.581	1	61	IPR002100	Transcription factor, MADS-box
SMART	SM00432	8.4E-38	1	60	IPR002100	Transcription factor, MADS-box
CDD	cd00265	1.65E-34	2	62	No hit	No description
SuperFamily	SSF55455	4.32E-28	2	70	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.5E-30	3	23	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	3.5E-24	10	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.5E-30	23	38	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.5E-30	38	59	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS51297	16.165	112	202	IPR002487	Transcription factor, K-box
Pfam	PF01486	1.5E-27	113	196	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 299 aa Download sequence Send to blast
MGRGRVQLKR IENKINRQVT FSKRTSGLLK KAHEISVLCD AEVALIVFST KGKLFEYSTD 60 SCCSLRDQCT TGKGERQTGY SAGVCVRERE MEREREYIIL RIYVKHGKDP GKGNWTLEHA 120 KLKARVEVLQ RNQSHYMGED LQILSFQELQ NLEQQLDSAL RRIRSRKNQV MYESISELQK 180 KDKALQEQNN LLAKNVKEKE KAVTSQAQLE HAQKQSLDSS STLLPQELQY LNFRYEESMV 240 ERRRGEEERM YKECRSNYHQ AIRSSNGISG DNQQDGDETA TPHRPNTLLP PWMLRHLNE

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5f28_A	2e-18	1	60	1	61	MEF2C
5f28_B	2e-18	1	60	1	61	MEF2C
5f28_C	2e-18	1	60	1	61	MEF2C
5f28_D	2e-18	1	60	1	61	MEF2C
6byy_A	2e-18	1	60	1	61	MEF2 CHIMERA
6byy_B	2e-18	1	60	1	61	MEF2 CHIMERA
6byy_C	2e-18	1	60	1	61	MEF2 CHIMERA
6byy_D	2e-18	1	60	1	61	MEF2 CHIMERA
6bz1_A	2e-18	1	60	1	61	MEF2 CHIMERA
6bz1_B	2e-18	1	60	1	61	MEF2 CHIMERA
6bz1_C	2e-18	1	60	1	61	MEF2 CHIMERA
6bz1_D	2e-18	1	60	1	61	MEF2 CHIMERA
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mdo.2940	1e-137	bud\| fruit

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed during the early stages of tuberization. {ECO:0000269\|PubMed:8756601}.
Uniprot	TISSUE SPECIFICITY: Abundant in vegetative organs. {ECO:0000269\|PubMed:8543185}.

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB623165	1e-141	AB623165.2 Pyrus pyrifolia var. culta PpMADS3-1 mRNA for MASDS-box protein, complete cds.
GenBank	KP164001	1e-141	KP164001.1 Pyrus pyrifolia clone PpAP1-2 AP1 MADS-box protein mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008374663.1	1e-158	truncated transcription factor CAULIFLOWER A isoform X1
Swissprot	Q42429	2e-89	AGL8_SOLTU; Agamous-like MADS-box protein AGL8 homolog
TrEMBL	Q283Q2	1e-156	Q283Q2_MALDO; MdMads2.2 protein
STRING	XP_008374663.1	1e-157	(Malus domestica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF588	32	119

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G60910.1	1e-81	AGAMOUS-like 8

Link Out ? help Back to Top
Phytozome	MDP0000218020

Publications ? help Back to Top
Kang SG,Hannapel DJ Nucleotide sequences of novel potato (Solanum tuberosum L.) MADS-box cDNAs and their expression in vegetative organs. Gene, 1995. 166(2): p. 329-30 [PMID:8543185]