PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10032439
Organism
Linum usitatissimum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family E2F/DP
Protein Properties Length: 401aa    MW: 44660.9 Da    PI: 7.0668
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10032439genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP73.32.7e-232085171
      E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                 rk+ksL+ll+++fl+l+++  +++v l+++a +L    v  +rRRiYDi+NVLe+++++ +++kn+++wkg
  Lus10032439 20 RKQKSLGLLCTNFLNLYNRDGTEVVGLDDAAARL---GV--ERRRIYDIVNVLESVGVLCRRAKNQYTWKG 85
                 79********************************...**..****************************98 PP
2E2F_TDP73.42.4e-23167247171
      E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                  rkeksL+lltq+f+kl+ +s+++ ++l++ ak L+ +       ++k+RR+YDi+NVL++l+liek     ++k+++rw+g
  Lus10032439 167 RKEKSLGLLTQNFVKLFLCSKAELISLDNSAKLLLGDghslsILRTKVRRLYDIANVLSSLKLIEKthtadSRKPAFRWMG 247
                  79***************************************98899**********************9999*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.7E-261686IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467854.19E-161983IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.0E-272085IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.4E-202185IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.4E-23162249IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013727.5E-28167247IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.2E-17168247IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.09E-11169248IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 401 aa     Download sequence    Send to blast
MNSGLTNETE SSSRHHSYSR KQKSLGLLCT NFLNLYNRDG TEVVGLDDAA ARLGVERRRI  60
YDIVNVLESV GVLCRRAKNQ YTWKGFAAMP ETLRGLKVQG MKENFGLSDT KNDNGAKVPS  120
GDGNEVEEDD EEEDVRDLES ITGSQNEAAA ADSGNGKSAA ASKQDNRKEK SLGLLTQNFV  180
KLFLCSKAEL ISLDNSAKLL LGDGHSLSIL RTKVRRLYDI ANVLSSLKLI EKTHTADSRK  240
PAFRWMGLNK SHESSSNAPL PDICESRKRV FGADVTNISF KRNKLDSSAH DDDKIRKSKM  300
HSDQVKVDNE VIGIEGAILS QESVHESRSY QFGPFGPAAL LRDSGTVREA NEVRDWDTLG  360
STFRPQYHNQ ALRDLFVHYM EAWQSWYTEV SEKKPIQQIS *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A5e-39192393228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10032439
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHQ8875513e-31HQ887551.1 Linum usitatissimum clone GMU2AYZ01AXKAY microsatellite sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002511465.11e-164E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-123E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLB9R8Z01e-163B9R8Z0_RICCO; E2F, putative
STRINGLus100324390.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-125DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]