PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Lsa018779

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

MYB_related

Protein Properties

Length: 291aa MW: 31670.6 Da PI: 10.1835

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58682549	PU_ref	Unigene	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	41.3	3.7e-13	114	158	3	47
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 +W+++E+ l++ + ++lG+g+W+ I+r ++Rt+ q+ s+ qky Lsa018779 114 PWSEDEHRLFLTGLEKLGKGDWRGISRNYVTTRTPTQVASHAQKY 158 7*******************************************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50158	8.565	3	20	IPR001878	Zinc finger, CCHC-type
PROSITE profile	PS51294	17.642	107	163	IPR017930	Myb domain
SuperFamily	SSF46689	6.88E-17	108	164	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	1.0E-17	110	162	IPR006447	Myb domain, plants
SMART	SM00717	7.3E-9	111	161	IPR001005	SANT/Myb domain
Pfam	PF00249	6.4E-11	114	158	IPR001005	SANT/Myb domain
CDD	cd00167	1.39E-9	114	159	No hit	No description
Gene3D	G3DSA:1.10.10.60	7.3E-10	114	157	IPR009057	Homeodomain-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 291 aa Download sequence Send to blast
MGRKCSHCGN IGHNSRTCTS YNRGNVNSTI LIGGGGGGGL RLFGVQLDTP HSMVIKKCLS 60 MDCLASSSPL QASTSHSPSS SLSSSRVSAS DLKSMSLGYA SDGLRAQERK KGFPWSEDEH 120 RLFLTGLEKL GKGDWRGISR NYVTTRTPTQ VASHAQKYFL RQASLVKKKR RSSLFDLVRG 180 NNKKNVVANQ ENSYNMSRTN SFDEGHQDRS NNISLIDFSS LKQENVYYNP TVKSYETTSM 240 CSHVHASPCG TIGSKSGTLD LELTLAAPKP VENNKSSATT SLQIGPIIRV I

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	166	170	KKKRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription repressor that binds to 5'-TATCCA-3' elements in gene promoters. Contributes to the sugar-repressed transcription of promoters containing SRS or 5'-TATCCA-3' elements. Transcription repressor involved in a cold stress response pathway that confers cold tolerance. Suppresses the DREB1-dependent signaling pathway under prolonged cold stress. DREB1 responds quickly and transiently while MYBS3 responds slowly to cold stress. They may act sequentially and complementarily for adaptation to short- and long-term cold stress (PubMed:20130099). {ECO:0000269\|PubMed:12172034, ECO:0000269\|PubMed:20130099}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by sucrose and gibberellic acid (GA) (PubMed:12172034). Induced by cold stress in roots and shoots. Induced by salt stress in shoots. Down-regulated by abscisic aci (ABA) in shoots (PubMed:20130099). {ECO:0000269\|PubMed:12172034, ECO:0000269\|PubMed:20130099}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023744342.1	0.0	transcription factor KUA1 isoform X2
Swissprot	Q7XC57	9e-46	MYBS3_ORYSJ; Transcription factor MYBS3
TrEMBL	A0A2J6JS90	0.0	A0A2J6JS90_LACSA; Uncharacterized protein
STRING	EOY30492	1e-75	(Theobroma cacao)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G56840.1	2e-51	MYB_related family protein

Publications ? help Back to Top
Rice Chromosome 10 Sequencing Consortium In-depth view of structure, activity, and evolution of rice chromosome 10. Science, 2003. 300(5625): p. 1566-9 [PMID:12791992] Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Su CF, et al. A novel MYBS3-dependent pathway confers cold tolerance in rice. Plant Physiol., 2010. 153(1): p. 145-58 [PMID:20130099]