PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Protein Features |

3D Structure |

Gene Ontology |

Function |

Publication

Basic Information? help Back to Top

TF ID

Lsa004258

Organism

Lactuca sativa

Taxonomic ID

4236

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Cichorioideae; Cichorieae; Lactucinae; Lactuca

Family

HSF

Protein Properties

Length: 310aa MW: 35474.1 Da PI: 5.5419

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Lsa#S58679375	PU_ref	Unigene	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	107.8	8.6e-34	10	101	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 F+ k+y++++d++l+ +i+w +nsf+v+++ +f++++Lp yFkh+nf+SFvRQLn+YgF+kv+ ++ weF++++F +g+++ll++i+ Lsa004258 10 FILKTYQMVNDASLDGFIRWGIANNSFIVVEPLDFSQRLLPAYFKHNNFSSFVRQLNTYGFRKVDPDK---------WEFANEWFLRGQTQLLKNIE 97 9******************888*************************************999.........****************** PP XXXX CS HSF_DNA-bind 99 rkks 102 rk++ Lsa004258 98 RKRQ 101 *986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00415	1.5E-48	6	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	5.58E-31	7	99	IPR011991	Winged helix-turn-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	6.1E-35	8	99	IPR011991	Winged helix-turn-helix DNA-binding domain
PRINTS	PR00056	2.1E-16	10	33	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	1.5E-28	10	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.1E-16	48	60	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	49	73	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.1E-16	61	73	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 310 aa Download sequence Send to blast
MDSNDIIAPF ILKTYQMVND ASLDGFIRWG IANNSFIVVE PLDFSQRLLP AYFKHNNFSS 60 FVRQLNTYGF RKVDPDKWEF ANEWFLRGQT QLLKNIERKR QIHNRNFMRG EEDEEDEMAM 120 EIARLKQEQK ALEQELVGMN KRLEATERRP EQMMALLHKV AEDPEILPRM MLEKDQRSKR 180 LLKKKRQRNL IPPPPPSSSS RVKFEEEECQ IIEGWTTSSP EAYYGNEPFW QSSSSPNTPS 240 MAWPMSKVGS GGGGAAVNME YAPMNGINRY VNFTDGIGGG YDINYSGGPS PEPDVRPSPA 300 YPFSLLGGGF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	2e-22	7	99	26	129	Heat shock factor protein 1
5d5v_B	2e-22	7	99	26	129	Heat shock factor protein 1
5d5v_D	2e-22	7	99	26	129	Heat shock factor protein 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	182	187	KKKRQR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023760271.1	0.0	heat stress transcription factor C-1-like
Swissprot	Q9LV52	2e-79	HSFC1_ARATH; Heat stress transcription factor C-1
TrEMBL	A0A2J6LLF0	0.0	A0A2J6LLF0_LACSA; Uncharacterized protein
STRING	XP_009588171.1	1e-103	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G24520.1	2e-77	heat shock transcription factor C1

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guan Q,Yue X,Zeng H,Zhu J The protein phosphatase RCF2 and its interacting partner NAC019 are critical for heat stress-responsive gene regulation and thermotolerance in Arabidopsis. Plant Cell, 2014. 26(1): p. 438-53 [PMID:24415771]