PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Loteae; Lotus

Family

Nin-like

Protein Properties

Length: 976aa MW: 107671 Da PI: 5.2371

Description

Nin-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Lj5g3v1999250.2	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	RWP-RK	90.6	1.2e-28	586	636	2	52
RWP-RK 2 ekeisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkiksl 52 ek+isle+l++yF++++kdAAk+Lgvc+T++KriCRq+GI+RWP+Rki+++ Lj5g3v1999250.2 586 EKSISLEVLQRYFAGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKINKV 636 799**********************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51519	17.677	575	656	IPR003035	RWP-RK domain
Pfam	PF02042	1.7E-25	589	636	IPR003035	RWP-RK domain
SuperFamily	SSF54277	8.83E-23	879	966	No hit	No description
SMART	SM00666	1.4E-25	881	963	IPR000270	PB1 domain
Gene3D	G3DSA:3.10.20.240	8.4E-26	881	962	No hit	No description
Pfam	PF00564	1.2E-18	881	962	IPR000270	PB1 domain
PROSITE profile	PS51745	25.247	881	963	IPR000270	PB1 domain
CDD	cd06407	2.92E-38	882	962	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0010118	Biological Process	stomatal movement
GO:0010167	Biological Process	response to nitrate
GO:0042128	Biological Process	nitrate assimilation
GO:0005634	Cellular Component	nucleus
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 976 aa Download sequence Send to blast
MSESDEEKPD FPQKARPTEE PGFAMDFDLD LESSWPMDHM SFVSNPMSPF LFSTMSDQPC 60 SPLWAFSDGE DDRHTSLAAP AFSDCHKIFP CDSNSVTEKP MENDDNNKLL PPVVPQPPIE 120 NLDRFCVIKE RMTQALRHFK ELTELNVLAQ VWAPVRNGNR YVLTTSGQPF VLDPHSNGLH 180 QYRTASLMYM FSADGENDGT LGLPGRVFQH KLPEWTPNVL YYSNKEYPRR DHAEHYNVRG 240 TLALPVFEPA LQSCVGVLEL IMTSQKINYG PEVEKICKAL EAVNLKSSEI LEPPYTQICN 300 EGRQNALSEI LEILTVVCET HNLPLAQTWV PCRHRSVLAH GGGLKKICSS FDGSCMGQVC 360 MSITDVASYI IDPHLWGFRE ACVEHHLQQG QGVAGRAFSS HSMCFCPNIT QFCKTDYPLV 420 HYALMFGLTS CFAICLRSSH TGDDDYVLEF FLPPRITHFS EQKTLVGSIL ATMKQHFQSL 480 KIAAGVELED GGSVEIIEAT NERVTLRLES IPIAQSVQSP PGPGGSPNMV EEVPKDPSEQ 540 QTMMNCNDMN EGGAHGDNAG GNIDQMSSLE TKTMKKPSER KRGKTEKSIS LEVLQRYFAG 600 SLKDAAKSLG VCPTTMKRIC RQHGISRWPS RKINKVNRSL SKLKRVIESV QGAEGAFGLN 660 SLSTSPLPVV GSFPEPSTPN KFSQQASMRP LESQMKENEI DASKILEIED PLLGGMTQNL 720 EKVFNDKGPR RIRTGSGSSE DSTNPTSHGS CYGSPPIESS HVKDISITSN NERCVVPRGS 780 PESSPLQPIN TLNSPSPIPI PDIVLTELQE PFGGMLIEDA GSSKDLRNLC PSAAEAILED 840 QVPEACPTNN PPGCSSLAPK RPVDTLGKTV TPFAAKKEMK TVTIKATYRE DIIRFRVSLT 900 CGIVELKEEV SKRLKLEVGT FDIKYLDDDQ EWVLIACDAD LQECIDVSRS SASHIIRVLV 960 HDITSNLGSS CESSGE

Sequence ? help Back to Top

Protein Sequence Length: 976 aa Download sequence Send to blast

MSESDEEKPD FPQKARPTEE PGFAMDFDLD LESSWPMDHM SFVSNPMSPF LFSTMSDQPC  60
SPLWAFSDGE DDRHTSLAAP AFSDCHKIFP CDSNSVTEKP MENDDNNKLL PPVVPQPPIE  120
NLDRFCVIKE RMTQALRHFK ELTELNVLAQ VWAPVRNGNR YVLTTSGQPF VLDPHSNGLH  180
QYRTASLMYM FSADGENDGT LGLPGRVFQH KLPEWTPNVL YYSNKEYPRR DHAEHYNVRG  240
TLALPVFEPA LQSCVGVLEL IMTSQKINYG PEVEKICKAL EAVNLKSSEI LEPPYTQICN  300
EGRQNALSEI LEILTVVCET HNLPLAQTWV PCRHRSVLAH GGGLKKICSS FDGSCMGQVC  360
MSITDVASYI IDPHLWGFRE ACVEHHLQQG QGVAGRAFSS HSMCFCPNIT QFCKTDYPLV  420
HYALMFGLTS CFAICLRSSH TGDDDYVLEF FLPPRITHFS EQKTLVGSIL ATMKQHFQSL  480
KIAAGVELED GGSVEIIEAT NERVTLRLES IPIAQSVQSP PGPGGSPNMV EEVPKDPSEQ  540
QTMMNCNDMN EGGAHGDNAG GNIDQMSSLE TKTMKKPSER KRGKTEKSIS LEVLQRYFAG  600
SLKDAAKSLG VCPTTMKRIC RQHGISRWPS RKINKVNRSL SKLKRVIESV QGAEGAFGLN  660
SLSTSPLPVV GSFPEPSTPN KFSQQASMRP LESQMKENEI DASKILEIED PLLGGMTQNL  720
EKVFNDKGPR RIRTGSGSSE DSTNPTSHGS CYGSPPIESS HVKDISITSN NERCVVPRGS  780
PESSPLQPIN TLNSPSPIPI PDIVLTELQE PFGGMLIEDA GSSKDLRNLC PSAAEAILED  840
QVPEACPTNN PPGCSSLAPK RPVDTLGKTV TPFAAKKEMK TVTIKATYRE DIIRFRVSLT  900
CGIVELKEEV SKRLKLEVGT FDIKYLDDDQ EWVLIACDAD LQECIDVSRS SASHIIRVLV  960
HDITSNLGSS CESSGE

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and siliques. Detected in root hairs, emerging secondary roots, vascular tissues, leaf parenchyma cells and stomata. {ECO:0000269\|PubMed:18826430}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. {ECO:0000269\|PubMed:18826430}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00449	DAP	Transfer from AT4G24020	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Lj5g3v1999250.2

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by the N source or by nitrate. {ECO:0000269\|PubMed:18826430}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027363207.1	0.0	protein NLP6-like isoform X1
Swissprot	Q84TH9	0.0	NLP7_ARATH; Protein NLP7
TrEMBL	A0A2Z5V8A6	0.0	A0A2Z5V8A6_LOTJA; Nodule inception-like protein
STRING	GLYMA20G29960.2	0.0	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4257	34	56

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G24020.1	0.0	NIN like protein 7

Publications ? help Back to Top
Xu N, et al. The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators. Plant Cell, 2016. 28(2): p. 485-504 [PMID:26744214] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Yu LH, et al. Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Sci Rep, 2016. 6: p. 27795 [PMID:27293103] Menz J,Li Z,Schulze WX,Ludewig U Early nitrogen-deprivation responses in Arabidopsis roots reveal distinct differences on transcriptome and (phospho-) proteome levels between nitrate and ammonium nutrition. Plant J., 2016. 88(5): p. 717-734 [PMID:27419465] Yan D, et al. NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 13179 [PMID:27731416] Guan P, et al. Interacting TCP and NLP transcription factors control plant responses to nitrate availability. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(9): p. 2419-2424 [PMID:28202720] Liu KH, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature, 2017. 545(7654): p. 311-316 [PMID:28489820] Li Z, et al. The Arabidopsis CPSF30-L gene plays an essential role in nitrate signaling and regulates the nitrate transceptor gene NRT1.1. New Phytol., 2017. 216(4): p. 1205-1222 [PMID:28850721] Cao H, et al. Overexpression of the Maize ZmNLP6 and ZmNLP8 Can Complement the Arabidopsis Nitrate Regulatory Mutant nlp7 by Restoring Nitrate Signaling and Assimilation. Front Plant Sci, 2017. 8: p. 1703 [PMID:29051766] Konishi N,Okubo T,Yamaya T,Hayakawa T,Minamisawa K Nitrate Supply-Dependent Shifts in Communities of Root-Associated Bacteria in Arabidopsis. Microbes Environ., 2017. 32(4): p. 314-323 [PMID:29187692] Karve RA,Iyer-Pascuzzi AS Further insights into the role of NIN-LIKE PROTEIN 7 (NLP7) in root cap cell release. Plant Signal Behav, 2018. 13(1): p. e1414122 [PMID:29215953] Zhao L, et al. The Arabidopsis NLP7 gene regulates nitrate signaling via NRT1.1-dependent pathway in the presence of ammonium. Sci Rep, 2018. 8(1): p. 1487 [PMID:29367694]