PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Loteae; Lotus

Family

NAC

Protein Properties

Length: 328aa MW: 38183.2 Da PI: 5.4963

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Lj2g3v1706540.1	genome	Kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	177.6	3.4e-55	9	138	1	129
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdke 91 +ppGfrFhPtdeelv +yL+kk++++k++l +vi+e+d+y++ePwdL + ++ e++ewyfFs++dkky+tg+r+nrat +g+Wkatg+dk+ Lj2g3v1706540.1 9 VPPGFRFHPTDEELVGYYLRKKIASQKIDL-DVIREIDLYRIEPWDLIErcRIGYeEQSEWYFFSHKDKKYPTGTRTNRATMAGFWKATGRDKA 101 69**************************.9***********743433332566******************************* PP NAM 92 vlskkgelvglkktLvfykgrapkgektdWvmheyrle 129 v++ k +l+g++ktLvfykgrap+g+ktdW+mheyrle Lj2g3v1706540.1 102 VYD-KMKLIGMRKTLVFYKGRAPNGQKTDWIMHEYRLE 138 .999****************************85 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	3.4E-60	5	158	IPR003441	NAC domain
PROSITE profile	PS51005	59.261	9	158	IPR003441	NAC domain
Pfam	PF02365	7.5E-29	10	137	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010200	Biological Process	response to chitin
GO:0048759	Biological Process	xylem vessel member cell differentiation
GO:1901348	Biological Process	positive regulation of secondary cell wall biogenesis
GO:1990110	Biological Process	callus formation
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 328 aa Download sequence Send to blast
MMESMESCVP PGFRFHPTDE ELVGYYLRKK IASQKIDLDV IREIDLYRIE PWDLIERCRI 60 GYEEQSEWYF FSHKDKKYPT GTRTNRATMA GFWKATGRDK AVYDKMKLIG MRKTLVFYKG 120 RAPNGQKTDW IMHEYRLETD ENGPPQEEGW VVCRAFKKKT TNSQTKTMEG WDSSYFYDEA 180 SVVSSVVDPL DLISRQPPQR FLAQSFMCKQ EIEAENLRHH MNPEQFIQLP QLESPSVPLM 240 KRPSTVVSLV SDNNNEDHDD QNRLLLSNKK VTDWRDLDKF VASQLSQETE GLPSFENHGG 300 SDMALFEGTK LSPFLSTSEI LTSLWLFN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	5e-51	6	160	12	170	Stress-induced transcription factor NAC1
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Up-regulated during xylem vessel element formation. Expressed preferentially in procambial cells adjacent to root meristem. {ECO:0000269\|PubMed:16103214, ECO:0000269\|PubMed:25148240}.
Uniprot	TISSUE SPECIFICITY: Expressed in root metaxylem pole and in shoot pre-procambium and procambium (PubMed:18445131). Present in root developing xylems (PubMed:16103214). Specifically expressed in vessels but not in interfascicular fibers in stems (PubMed:25148240). {ECO:0000269\|PubMed:16103214, ECO:0000269\|PubMed:18445131, ECO:0000269\|PubMed:25148240}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls (PubMed:25148240). {ECO:0000250\|UniProtKB:Q9LVA1, ECO:0000269\|PubMed:25148240}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00266	DAP	Transfer from AT2G18060	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Lj2g3v1706540.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by chitin (e.g. chitooctaose) (PubMed:17722694). Accumulates in plants exposed to callus induction medium (CIM) (PubMed:17581762). {ECO:0000269\|PubMed:17581762, ECO:0000269\|PubMed:17722694}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT147274	1e-166	BT147274.1 Medicago truncatula clone JCVI-FLMt-4I24 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027361660.1	0.0	NAC domain-containing protein 37-like
Refseq	XP_027361661.1	0.0	NAC domain-containing protein 37-like
Swissprot	Q9SL41	1e-149	NAC37_ARATH; NAC domain-containing protein 37
TrEMBL	A0A061DFT4	0.0	A0A061DFT4_THECC; Vascular related NAC-domain protein 1 isoform 1
TrEMBL	A0A4D6LSR5	0.0	A0A4D6LSR5_VIGUN; Uncharacterized protein
STRING	EOX90892	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4565	34	59

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G18060.1	1e-148	vascular related NAC-domain protein 1

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Negi S,Tak H,Ganapathi TR Cloning and functional characterization of MusaVND1 using transgenic banana plants. Transgenic Res., 2015. 24(3): p. 571-85 [PMID:25523085] Tan TT, et al. Transcription Factors VND1-VND3 Contribute to Cotyledon Xylem Vessel Formation. Plant Physiol., 2018. 176(1): p. 773-789 [PMID:29133368]