PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Leersia

Family

C2H2

Protein Properties

Length: 512aa MW: 55068 Da PI: 5.7604

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
LPERR12G04020.1	genome	OGE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21	8.5e-07	258	279	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C++Cgk F+r nL+ H+r H LPERR12G04020.1 258 FCTICGKGFKRDANLRMHMRGH 279 6*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	6.09E-6	256	279	No hit	No description
PROSITE profile	PS50157	12.03	257	284	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0026	257	279	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.3E-5	258	283	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF12874	0.001	258	279	No hit	No description
PROSITE pattern	PS00028	0	259	279	IPR007087	Zinc finger, C2H2
SMART	SM00355	60	305	338	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	6.09E-6	338	364	No hit	No description
SMART	SM00355	47	343	365	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010044	Biological Process	response to aluminum ion
GO:0043620	Biological Process	regulation of DNA-templated transcription in response to stress
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 512 aa Download sequence Send to blast
MEGQRNFRRE IFCFPSTAHA IFLRRFDMNR DQAAKLSPMN PLCYPFMSEE ALLAMGMPPA 60 PAPPPPPQLM PSASIRHMDW SPDTMLNNLT FIEEKIRQVK DVIRAMAGRS SATATAPDQQ 120 QLVNADLTCL IVQLISTAGS LLPSLKNSSF LSRSTPPPAA GAGAGGGGGS LAAGESSSSV 180 RNEGNKEEEE EEMGSPDYEE LFRGWANGDV LAAGDEELDV KVDAADVDGE NPPPPAAAGT 240 YQVLQLEEDE ILAPHTHFCT ICGKGFKRDA NLRMHMRGHG DEYKSAAALA KPPVVVGEEE 300 PERRYSCPFV GCKRNRQHAS FQPLKTILCV KNHYKRTHTE KRHVCGRCGA KRFSVMADLK 360 THEKHCGRDK WLCSCGTTFS RKDKLFAHVA LFQGHAPALP PPSPPVTAPT GQRRQKKEEE 420 VVAGDVGFVW GGGGGASTSC NDDDGLLDVK GIASVGVGAG GDEFFSPGGF GSTIDFGFGQ 480 LDVFPGDSSL GMQMLLSSEQ FTAGDQEGNG EK

Sequence ? help Back to Top

Protein Sequence Length: 512 aa Download sequence Send to blast

MEGQRNFRRE IFCFPSTAHA IFLRRFDMNR DQAAKLSPMN PLCYPFMSEE ALLAMGMPPA  60
PAPPPPPQLM PSASIRHMDW SPDTMLNNLT FIEEKIRQVK DVIRAMAGRS SATATAPDQQ  120
QLVNADLTCL IVQLISTAGS LLPSLKNSSF LSRSTPPPAA GAGAGGGGGS LAAGESSSSV  180
RNEGNKEEEE EEMGSPDYEE LFRGWANGDV LAAGDEELDV KVDAADVDGE NPPPPAAAGT  240
YQVLQLEEDE ILAPHTHFCT ICGKGFKRDA NLRMHMRGHG DEYKSAAALA KPPVVVGEEE  300
PERRYSCPFV GCKRNRQHAS FQPLKTILCV KNHYKRTHTE KRHVCGRCGA KRFSVMADLK  360
THEKHCGRDK WLCSCGTTFS RKDKLFAHVA LFQGHAPALP PPSPPVTAPT GQRRQKKEEE  420
VVAGDVGFVW GGGGGASTSC NDDDGLLDVK GIASVGVGAG GDEFFSPGGF GSTIDFGFGQ  480
LDVFPGDSSL GMQMLLSSEQ FTAGDQEGNG EK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that regulates the expression of genes involved in aluminum (Al) tolerance. Binds to the promoter of STAR1 and regulates transcript expression of STAR1 STAR2 and ART1 required for Al tolerance. {ECO:0000269\|PubMed:19880795}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	LPERR12G04020.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015620753.1	0.0	zinc finger protein STAR3
Swissprot	Q2QX40	0.0	ART1_ORYSJ; Zinc finger protein STAR3
TrEMBL	A0A0D9XXC2	0.0	A0A0D9XXC2_9ORYZ; Uncharacterized protein
STRING	LPERR12G04020.1	0.0	(Leersia perrieri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP1512	38	111

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	1e-111	C2H2 family protein

Publications ? help Back to Top
Xia J,Yamaji N,Kasai T,Ma JF Plasma membrane-localized transporter for aluminum in rice. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(43): p. 18381-5 [PMID:20937890] Tsutsui T,Yamaji N,Feng Ma J Identification of a cis-acting element of ART1, a C2H2-type zinc-finger transcription factor for aluminum tolerance in rice. Plant Physiol., 2011. 156(2): p. 925-31 [PMID:21502187] Famoso AN, et al. Genetic architecture of aluminum tolerance in rice (Oryza sativa) determined through genome-wide association analysis and QTL mapping. PLoS Genet., 2011. 7(8): p. e1002221 [PMID:21829395] Yokosho K,Yamaji N,Ma JF An Al-inducible MATE gene is involved in external detoxification of Al in rice. Plant J., 2011. 68(6): p. 1061-9 [PMID:21880027] Huang CF,Yamaji N,Chen Z,Ma JF A tonoplast-localized half-size ABC transporter is required for internal detoxification of aluminum in rice. Plant J., 2012. 69(5): p. 857-67 [PMID:22035218] Chen ZC,Yamaji N,Motoyama R,Nagamura Y,Ma JF Up-regulation of a magnesium transporter gene OsMGT1 is required for conferring aluminum tolerance in rice. Plant Physiol., 2012. 159(4): p. 1624-33 [PMID:22732245] Tsutsui T, et al. Comparative genome-wide transcriptional analysis of Al-responsive genes reveals novel Al tolerance mechanisms in rice. PLoS ONE, 2012. 7(10): p. e48197 [PMID:23110212] Chen ZC, et al. Adaptation to acidic soil is achieved by increased numbers of cis-acting elements regulating ALMT1 expression in Holcus lanatus. Plant J., 2013. 76(1): p. 10-23 [PMID:23773148] Xia J,Yamaji N,Ma JF A plasma membrane-localized small peptide is involved in rice aluminum tolerance. Plant J., 2013. 76(2): p. 345-55 [PMID:23888867] Yokosho K,Yamaji N,Fujii-Kashino M,Ma JF Functional Analysis of a MATE Gene OsFRDL2 Revealed its Involvement in Al-Induced Secretion of Citrate, but a Lower Contribution to Al Tolerance in Rice. Plant Cell Physiol., 2016. 57(5): p. 976-85 [PMID:26872836] Che J,Yamaji N,Shen RF,Ma JF An Al-inducible expansin gene, OsEXPA10 is involved in root cell elongation of rice. Plant J., 2016. 88(1): p. 132-142 [PMID:27302336] Yokosho K,Yamaji N,Fujii-Kashino M,Ma JF Retrotransposon-Mediated Aluminum Tolerance through Enhanced Expression of the Citrate Transporter OsFRDL4. Plant Physiol., 2016. 172(4): p. 2327-2336 [PMID:27744299]