PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Leersia

Family

ERF

Protein Properties

Length: 176aa MW: 18703.8 Da PI: 6.5421

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
LPERR05G10570.1	genome	OGE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	60.3	4.4e-19	46	94	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+G+r+++ +grW+AeIrdp++ +r++lg++ tae+Aa+a++ a++ ++g LPERR05G10570.1 46 YRGIRRRP-WGRWAAEIRDPRK---GARVWLGTYATAEDAARAYDVAARDIRG 94 9*****.******954...4*********************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00380	1.5E-33	45	108	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.11E-22	45	104	IPR016177	DNA-binding domain
Pfam	PF00847	4.6E-13	45	94	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.3E-32	45	102	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.724	45	102	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.7E-11	46	57	IPR001471	AP2/ERF domain
CDD	cd00018	8.22E-28	46	104	No hit	No description
PRINTS	PR00367	4.7E-11	68	84	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008219	Biological Process	cell death
GO:0009723	Biological Process	response to ethylene
GO:0009735	Biological Process	response to cytokinin
GO:0009753	Biological Process	response to jasmonic acid
GO:0010286	Biological Process	heat acclimation
GO:0034059	Biological Process	response to anoxia
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0051707	Biological Process	response to other organism
GO:0005634	Cellular Component	nucleus
GO:0005737	Cellular Component	cytoplasm
GO:0005886	Cellular Component	plasma membrane
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 176 aa Download sequence Send to blast
MCGGAIIADF VPSPAARHPT DDDTNFSGEE ESSLAKTAPG GRKTAYRGIR RRPWGRWAAE 60 IRDPRKGARV WLGTYATAED AARAYDVAAR DIRGAKAKLN FPPSIAIAAA HPPPKKRRRS 120 SAAAAAAAES SASSPPAAER QLRECMSGLE AFLGLEEEEG GDGAGEQWDA VDLMLE

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	4e-21	46	105	6	66	ATERF1
3gcc_A	4e-21	46	105	6	66	ATERF1
5wx9_A	4e-21	46	110	15	80	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:9159183}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00109	PBM	Transfer from AT3G16770	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	LPERR05G10570.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By 1-aminocyclopropane-1-carboxylic acid (ACC, ethylene precursor), methyl jasmonate (MeJA), and Botrytis cinerea. Also induced by cadmium. {ECO:0000269\|PubMed:18836139, ECO:0000269\|PubMed:9159183}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC134348	1e-71	AC134348.2 Oryza sativa Japonica Group cultivar Nipponbare chromosome 5 clone P0530H10, complete sequence.
GenBank	AC135929	1e-71	AC135929.2 Oryza sativa Japonica Group cultivar Nipponbare chromosome 5 clone P0692D12, complete sequence.
GenBank	AK100184	1e-71	AK100184.1 Oryza sativa Japonica Group cDNA clone:J023031H12, full insert sequence.
GenBank	AK111676	1e-71	AK111676.1 Oryza sativa Japonica Group cDNA clone:J013155B14, full insert sequence.
GenBank	AP014961	1e-71	AP014961.1 Oryza sativa Japonica Group DNA, chromosome 5, cultivar: Nipponbare, complete sequence.
GenBank	CP012613	1e-71	CP012613.1 Oryza sativa Indica Group cultivar RP Bio-226 chromosome 5 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006654302.1	2e-64	PREDICTED: ethylene-responsive transcription factor ERF071-like
Swissprot	O22259	6e-34	ERF71_ARATH; Ethylene-responsive transcription factor ERF071
Swissprot	P42736	4e-33	RAP23_ARATH; Ethylene-responsive transcription factor RAP2-3
TrEMBL	A0A0D9WFL8	1e-121	A0A0D9WFL8_9ORYZ; Uncharacterized protein
STRING	LPERR05G10570.1	1e-122	(Leersia perrieri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP103	37	465

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G47520.1	4e-23	ERF family protein

Publications ? help Back to Top
Bueso E, et al. The lithium tolerance of the Arabidopsis cat2 mutant reveals a cross-talk between oxidative stress and ethylene. Plant J., 2007. 52(6): p. 1052-65 [PMID:17931347] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Chen YC, et al. Root defense analysis against Fusarium oxysporum reveals new regulators to confer resistance. Sci Rep, 2014. 4: p. 5584 [PMID:24998294] Deslauriers SD,Alvarez AA,Lacey RF,Binder BM,Larsen PB Dominant gain-of-function mutations in transmembrane domain III of ERS1 and ETR1 suggest a novel role for this domain in regulating the magnitude of ethylene response in Arabidopsis. New Phytol., 2015. 208(2): p. 442-55 [PMID:25988998] Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana. Plant Sci., 2015. 236: p. 37-43 [PMID:26025519] Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Liu W, et al. Ethylene response factor AtERF72 negatively regulates Arabidopsis thaliana response to iron deficiency. Biochem. Biophys. Res. Commun., 2017. 491(3): p. 862-868 [PMID:28390898] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474] Eysholdt-Derzsó E,Sauter M Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling. Plant Physiol., 2017. 175(1): p. 412-423 [PMID:28698356] Eysholdt-Derzsó E,Sauter M Hypoxia and the group VII ethylene response transcription factor HRE2 promote adventitious root elongation in Arabidopsis. Plant Biol (Stuttg), 2019. 21 Suppl 1: p. 103-108 [PMID:29996004]