PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Leersia

Family

C2H2

Protein Properties

Length: 475aa MW: 50190 Da PI: 8.2085

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
LPERR01G37530.1	genome	OGE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	18.8	4.4e-06	81	103	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++Cgk F r nL+ H r H LPERR01G37530.1 81 FVCEICGKGFQRDQNLQLHRRGH 103 89*******************88 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	3.15E-7	80	103	No hit	No description
PROSITE profile	PS50157	11.614	81	103	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.012	81	103	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.3E-5	81	103	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	83	103	IPR007087	Zinc finger, C2H2
SMART	SM00355	310	125	155	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	6.2E-4	148	181	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.15E-7	155	180	No hit	No description
SMART	SM00355	190	160	188	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 475 aa Download sequence Send to blast
MEEFELQQQQ PPYYSKLLLG SPLEIANVDD GDLHHIAGAP SEPPPAPAPT VKKKRSLPGT 60 PDPSAEVIAL SPRTLLATNR FVCEICGKGF QRDQNLQLHR RGHNLPWKLR QRGGAGDQPP 120 RKRVYVCPEL SCVHHSASRA LGDLTGIKKH FCRKHGEKKW KCDRCGKRYA VHSDCKAHSK 180 VRDSFVTHRA FCDALSKENN KMAQPMNMAA VTSALQGQHH HHLVLHSTCH SDDPITAADE 240 HDTAAAAGYG LGAADVKISP HLTMFPDVAI PPALTMAGSM LSSLAVAAAR SAPPSPSPFF 300 HGRNNLDPAM AFPPPPPPGT SSSSSPAIMS ATALLQKAAE LGATTSSPAA SCYGSVGFPS 360 MVGVGPHGPD RIPALGHHLG PCDGVVVPAA AATTQLVGFD LGGLLPGQLY GGGGAMTRAI 420 GSLMHGDQLH AGVVDRRRRG GEGGVRVVDY MGVDDDEQGR FDGVGHFGPQ MGPWA

Sequence ? help Back to Top

Protein Sequence Length: 475 aa Download sequence Send to blast

MEEFELQQQQ PPYYSKLLLG SPLEIANVDD GDLHHIAGAP SEPPPAPAPT VKKKRSLPGT  60
PDPSAEVIAL SPRTLLATNR FVCEICGKGF QRDQNLQLHR RGHNLPWKLR QRGGAGDQPP  120
RKRVYVCPEL SCVHHSASRA LGDLTGIKKH FCRKHGEKKW KCDRCGKRYA VHSDCKAHSK  180
VRDSFVTHRA FCDALSKENN KMAQPMNMAA VTSALQGQHH HHLVLHSTCH SDDPITAADE  240
HDTAAAAGYG LGAADVKISP HLTMFPDVAI PPALTMAGSM LSSLAVAAAR SAPPSPSPFF  300
HGRNNLDPAM AFPPPPPPGT SSSSSPAIMS ATALLQKAAE LGATTSSPAA SCYGSVGFPS  360
MVGVGPHGPD RIPALGHHLG PCDGVVVPAA AATTQLVGFD LGGLLPGQLY GGGGAMTRAI  420
GSLMHGDQLH AGVVDRRRRG GEGGVRVVDY MGVDDDEQGR FDGVGHFGPQ MGPWA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	4e-15	156	207	3	70	Zinc finger protein JACKDAW
5b3h_F	4e-15	156	207	3	70	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	LPERR01G37530.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015635962.1	0.0	protein indeterminate-domain 12
Swissprot	Q9SCQ6	2e-84	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A0D9V9Y6	0.0	A0A0D9V9Y6_9ORYZ; Uncharacterized protein
STRING	LPERR01G37530.1	0.0	(Leersia perrieri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP12554	25	34

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	3e-82	indeterminate(ID)-domain 2

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]